Tıp Fakültesi / Faculty of Medicine

Permanent URI for this collectionhttps://hdl.handle.net/11727/1403

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Author: search.filters.author.Coban, G.

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    Could The Long-Term Oncological Safety of Laparoscopic Surgery in Low Risk Endometrial Cancer Be Also Valid For The High Intermediate And High-Risk Patients? A Multi-Center Turkish Gynecologic Oncology Group Study Conducted with 2745 Endometrial Cancer Cases
    (2019) Vardar, M. A.; Guzel, A. B.; Taskin, S.; Gungor, M.; Ozgul, N.; Salman, C.; Gulec, U. Kucukgoz; Khatib, G.; Dunder, I.; Ortac, F.; Yuce, K.; Terek, C.; Simsek, T.; Ozsaran, A.; Taskiran, C.; Onan, A.; Coban, G.; Topuz, S.; Demirkiran, F.; Takmaz, O.; Kose, M. F.; Gocmen, A.; Seydaoglu, G.; Gumurdulu, D.; Ayhan, A.; AAJ-5802-2021
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    Role of Initial Surgery in Malignant Ovarian Germ Cell Tumors
    (2016) Kocaman, E.; Coban, G.; Sahin, H.; Akilli, H.; Celik, H.; Kuscu, E.; Ayhan, A.; 0000-0002-3285-5519; 0000-0002-0992-6980; AAI-9974-2021; AAJ-5802-2021; AAI-8792-2021; AAL-1923-2021
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    Role of Initial Surgery in Malignant Ovarian Germ Cell Tumors
    (2017) Kocaman, E.; Coban, G.; Sahin, H.; Akilli, H.; Celik, H.; Kuscu, E.; Ayhan, A.; 0000-0002-3285-5519; 0000-0002-0992-6980; AAI-9974-2021; AAL-1923-2021; AAI-8792-2021; AAJ-5802-2021
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    Characteristics of Lgsoc; A Single Center Experience
    (2017) Akilli, H.; Coban, G.; Kocaman, E.; Haberal, N.; Ayhan, A.; 0000-0002-5240-8441; 0000-0002-3285-5519; 0000-0001-9852-9911; AAX-3230-2020; AAI-9974-2021; AAK-4587-2021; AAJ-5802-2021
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    The Role of Preoperative Routine Computed Tomography Scanning in The Estimation of High-Risk Factors in Endometrial Cancers
    (2018) Coban, G.; Erbay, G.; Kose, F.; Alemdaroglu, S.; Onal, C.; Celik, H.; https://orcid.org/0000-0002-3285-5519; https://orcid.org/0000-0002-1706-8680; https://orcid.org/0000-0002-0156-5973; https://orcid.org/0000-0003-4335-6659; https://orcid.org/0000-0002-2742-9021; AAI-9974-2021; AAK-5370-2021; G-4827-2016; AAI-8400-2021; HOC-5611-2023; AAL-1923-2021
    Objective: To examine the role of preoperative computed tomography (CT) in estimation of the high-risk factors in endometrial cancer cases. Materials and Methods: The data from 161 cases who were diagnosed with endometrioid adenocarcinoma with endometrial biopsy, and staged surgically were retrospectively analyzed. The diagnostic performance of a whole abdominal CT scan in terms of tumor diameter, myometrial invasion, cervical, adnexal, omental involvement, as well as pelvic para-aortic nodal involvement was examined. In addition, extra-uterine and extra-nodal incidental signs were identified. Results: The accuracy rate of preoperative CT scanning was found to be 42%, 78%, 80%, 95%, 97%, 88%, 89%, and 88% for tumor diameter, myometrial invasion, cervical, adnexal, and omental involvement, as well as pelvic para-aortic nodal involvement, respectively. Extra-uterine and extra-nodal incidental signs were identified in 18% of the cases. Incidental findings entailed a modification of management only in one case (0.62%). Conclusion: Preoperative CT scan findings do not present an alternative to intraoperative frozen section analysis or surgical staging. However, based on the findings from the preoperative CT scan, accuracy of predictions about which patients require more complex procedures (lymphadenectomy) can be improved, and therefore preoperative CT scanning may prove useful in more effective use of operating rooms.
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    Prognostic Value of Dynamic Susceptibility Contrast-Enhanced and Diffusion-Weighted MR Imaging in Patients with Glioblastomas
    (2015) Coban, G.; Mohan, S.; Kural, F.; Wang, S.; O'Rourke, D.M.; Poptani, H.; 25836728
    BACKGROUND AND PURPOSE: Prediction of survival in patients with glioblastomas is important for individualized treatment planning. This study aimed to assess the prognostic utility of presurgical dynamic susceptibility contrast and diffusion-weighted imaging for overall survival in patients with glioblastoma. MATERIALS AND METHODS: MR imaging data from pathologically proved glioblastomas between June 2006 to December 2013 in 58 patients (mean age, 62.7 years; age range, 22-89 years) were included in this retrospective study. Patients were divided into long survival (>= 15 months) and short survival (<15 months) groups, depending on overall survival time. Patients underwent dynamic susceptibility contrast perfusion and DWI before surgery and were treated with chemotherapy and radiation therapy. The maximum relative cerebral blood volume and minimum mean diffusivity values were measured from the enhancing part of the tumor. RESULTS: Maximum relative cerebral blood volume values in patients with short survival were significantly higher compared with those who demonstrated long survival (P < .05). No significant difference was observed in the minimum mean diffusivity between short and long survivors. Receiver operator curve analysis demonstrated that a maximum relative cerebral blood volume cutoff value of 5.79 differentiated patients with low and high survival with an area under the curve of 0.93, sensitivity of 0.89, and specificity of 0.90 (P < .001), while a minimum mean diffusivity cutoff value of 8.35 x 10(-4)mm(2)/s had an area under the curve of 0.55, sensitivity of 0.71, and specificity of 0.47 (P > .05) in separating the 2 groups. CONCLUSIONS: Maximum relative cerebral blood volume may be used as a prognostic marker of overall survival in patients with glioblastomas.