Tıp Fakültesi / Faculty of Medicine
Permanent URI for this collectionhttps://hdl.handle.net/11727/1403
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Item A Multicenter Survey: How Do Transplant Dermatologists Monitor Organ Transplant Recipients With Nevi?(2018) Ozcan, Deren; Seckin, Deniz; Haberal, Mehmet; 0000-0002-7450-6886; 0000-0002-3462-7632; 29528027; AAQ-6649-2021; AAJ-8097-2021Objectives: The incidence and mortality of melanoma are increased in organ transplant recipients. Multiple acquired common and dysplastic nevi are risk factors for melanoma. A new or changing nevus may suggest melanoma. Strategies used by transplant dermatologists to monitor nevi are unknown. Herein, we aimed to assess the methods used by transplant dermatologists for monitoring multiple acquired common nevi, dysplastic nevi, and new or changing nevi. Materials and Methods: A questionnaire was e-mailed to 63 members of the Skin Care in Organ Transplant Patients, Europe. Results: Thirty-eight (92.7%) of 41 responders reported that they instruct their patients to perform regular self-skin examinations. Of 41 responders, 41.5% prescribed screening every 6 months, 36.6% prescribed it every 12 months, 12.2% prescribed it every 3 months, and 9.7% performed screening without regular intervals. Regarding type of examination, 80.5% performed full-body skin examinations with the naked eye, 70.7% performed dermoscopy of clinically suspicious nevi, 53.6% offered dermoscopic photography of dermoscopically suspicious nevi, 36.6% provided close-up photography of clinically suspicious nevi, 34.1% performed baseline total body photography, and 24.4% conducted dermoscopy of all nevi. We also found that 7.3%, 4.9%, and 4.9% performed only full-body skin examination with the naked eye, only dermoscopy of clinically suspicious nevi, and only dermoscopy of all nevi, respectively. Conclusions: Dedicated transplant dermatologists perform a wide variety of nevi screening procedures in organ transplant recipients. Transplant dermatologists should include sequential digital dermoscopic imaging in their armamentarium to follow organ transplant recipients with melanocytic lesions. A combination of techniques is advisable for detecting early posttransplant melanomas.Item Evaluation of a Handheld Dermatoscope in Clinical Diagnosis of Primary Cicatricial Alopecias(2019) Kose, Ozlem Karadag; Gulec, A. Tulin; 31190216Introduction Clinical diagnosis of primary cicatricial alopecias presents difficulties. Studies regarding their trichoscopic features are scarce and mostly not comprehensive. The aim of this study is to evaluate the potential benefit of a handheld dermatoscope in clinical diagnosis of primary cicatricial alopecias. Methods In all, 69 patients with primary cicatricial alopecias were included in this prospective study. Preliminary diagnoses were established clinically, and confirmed by scalp biopsy in all cases. Trichoscopic examination was performed using a polarized-light handheld dermatoscope with tenfold magnification. The images were taken using a digital camera with threefold optical zoom. Results The following findings were significantly more common, or noted only, in particular types of primary cicatricial alopecias: "target" pattern blue-grey dots, perifollicular scaling, perifollicular cast in lichen planopilaris (n = 27); short vellus hairs, tufted hairs, crust formation, yellowish tubular scaling, pustule, red dots in folliculitis decalvans (n = 17); large keratotic yellow dots in discoid lupus erythematosus (n = 7); yellow dots, yellow dots with "three-dimensional" structure, black dots in dissecting cellulitis of the scalp (n = 6). Absence of vellus hairs was observed in patients with lichen planopilaris, frontal fibrosing alopecia, and discoid lupus erythematosus without a significant difference between the groups. Short vellus hairs were detected in all types, including frontal fibrosing alopecia (n = 7). Conclusion We suggest that a polarized-light handheld dermatoscope is useful for revealing several typical trichoscopic features of primary cicatricial alopecias that guide clinical diagnosis. As a novel observation, our data indicate that absence of vellus hairs is not an identifying feature for frontal fibrosing alopecia.Item Evaluation of Treatment Response by Using a Handheld Dermoscope in Patients with Alopecia Areata(2018) Gulec, A. Tulin; Kose, Ozlem KaradagObjective: Treatment response is variable in patients with alopecia areata, and may not be understood until significant hair growth is obtained. The aim of this study is to determine the potential benefit of handheld dermoscope in evaluating of treatment success in alopecia areata. Methods: Forty-nine patients who were diagnosed with alopecia areata were included in the study. Diagnosis was established clinically, and scalp biopsy was performed in doubtful cases. Dermoscopic examinations were performed by a polarized light and handheld dermoscope with 10-fold magnification. The images were taken by a digital camera with threefold optical zoom. Among 49 patients, 30 of them were followed-up during six months and concluded the study. Results: Of the 30 patients, 12 had a complete response to treatment (group 1), whereas 18 patients did not respond well to treatment or were remained completely responseless (group 2). When the trichoscopic findings were examined pretreatment, only thinning hairs were significantly more frequent in group 1 than group 2. The pre- and posttreatment findings of group 1 was shown that yellow dots, black dots, thinning hairs and broken hairs decreased or disappeared after the treatment, and this difference was statistically significant. In all of the patients in the first group, short terminal hairs were appeared at the end of treatment. Conclusion: According to our study, polarized light handheld dermoscope provides benefit for the evaluation of treatment success in patients with alopecia areata.