Tıp Fakültesi / Faculty of Medicine
Permanent URI for this collectionhttps://hdl.handle.net/11727/1403
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Item Supra-Inguinal Fascia Iliaca Block in Older-Old Patients for Hip Fractures: A Retrospective Study(2023) Bali, Cagla; Ozmete, Ozlem; 34582902Background Pain management in hip fracture patients is of great importance for reducing postoperative morbidity and mortality. Multimodal techniques, including peripheral nerve blocks, are preferred for postoperative analgesia. Older-old hip fracture patients with high ASA scores are highly sensitive to the side effects of NSAIDs and opioids. Our aim was to investigate the effectiveness of the recently popularized Supra-Inguinal Fascia Iliaca Block (SIFIB) in this population.Methods Forty-one ASA III...IV patients who underwent SIFIB...+...PCA (G-SIFIB) or PCA alone (Group Control: GC) after general anesthesia were evaluated retrospectively. In addition to 24-hour opioid consumption, Visual Analog Scale (VAS) scores, opioid-related side effects, block-related complications, and length of hospital stay were compared.Results Twenty-two patients in G-SIFIB and 19 patients in GC were evaluated. The postoperative 24-hour opioid consumption was lower in G-SIFIB than in GC (p<0.001). There was a statistically significant reduction in VAS scores at the postoperative 1(st), 3(rd), and 6(th) hours at rest (p<0.001) and during movement (p<0.001 for the 1(st) and 3(rd) hours, and p=0.02 for the 6(th) hour) in G-SIFIB compared to GC. There was no difference in pain scores at the 12(th) and 24(th) hours postoperatively. While there was no difference between the groups in terms of other side effects, respiratory depression was significantly higher in GC than in G-SIFIB (p=0.01).Conclusion The SIFIB technique has a significant opioid-sparing effect and thus reduces opioid-related side effects in the first 24 hours after hip fracture surgery in older-old patients.Item Relationship Between Perioperative Factors and Splenic Artery Steal Syndrome After Orthotopic Liver Transplant: A Retrospective Clinical Study(2023) Kuscu, Ozlem Ozkan; Kus, Murat; Incekas, Caner; Ozmete, Ozlem; Ergenoglu, Pinar; Yildirim, Sedat; Torgay, Adnan; Haberal, Mehmet; 37885290Objectives: After orthotopic liver transplant, ischemia of biliary tract and graft loss may occur due to impaired hepatic arterial blood flow. This situation with hypersplenism and impaired hepatic arterial blood flow is defined as splenic artery steal syndrome. The aim of this study was to investigate the relationship between perioperative factors and splenic artery steal syndrome in orthotopic liver transplant patients. Materials and Methods: Forty-five patients who underwent orthotopic liver transplant between 2014 and 2022 were included in the study. The data for the patients were obtained from the hospital database, including the intraoperative anesthesiology and postoperative intensive care records. Results: Eleven patients were diagnosed with splenic artery steal syndrome. Patients with splenic artery steal syndrome had higher need for intraoperative vasopressor agents (P = .016) and exhibited lower intraoperative urine output (P = .031). In the postoperative intensive care follow-up, patients with splenic artery steal syndrome had higher levels of C-reactive protein during the first 48 hours (P = .030). Conclusions: Intraoperative administration of vasopressor drugs, low urine output, and early postoperative high C-reactive protein levels were associated with the development of splenic artery steal syndrome in patients undergoing orthotopic liver transplant. Future studies should focus on investigation of biomarkers associated systemic hypoperfusion that may contribute to the development of splenic artery steal syndrome.Item Scientific Publication Performance of the Erector Spinae Plane Block in Turkiye: A Bibliometric Analysis(2023) Catalca, Sibel; Ozmete, Ozlem; Ozyilkan, Nesrin Bozdogan; 38149368Objective: Erector spina plane block (ESPB) was first described in 2016 and is effective in various surgical procedures. Bibliometric analysis is a novel method that evaluates the contribution of scientific studies conducted in a specific field on the existing literature. This study examined articles on ESPB published by anaesthesia clinics in Turkiye in journals under the Science Citation Index Expanded (SCI-E) category. Methods: Studies on ESPB indexed in the Web of Science Core Collection and published in Turkiye from 2018 to 2022 were evaluated. The primary outcome was to determine the number of studies published in journals under the SCI-E category. The secondary aims were to determine the number of citations and the institutions where the studies were conducted. Results: A total of 159 publications were analyzed. The journal with the highest number of publications was "Journal of Clinical Anesthesia" (n = 70). The institution that has to date made the most contributions to the literature was Ataturk University (n = 31). The most cited article was "Ultrasound guided erector spinae plane block reduces postoperative opioid consumption following breast surgery: A randomized controlled study." published by Gurkan et al. (n = 175). Conclusion: This study reflects the contribution level of Turkiye-addressed anaesthesia clinics to journals under the SCI-E category. Our findings can serve as a benchmark for attracting the attention of national and international researchers.Item The Impact of Multimodal Analgesia Timing on Postoperative Pain in Cesarean Delivery. A Prospective Randomized Study(2023) Ozmete, Ozlem; Sener, Mesut; Bali, Cagla; Caligan, Esla; Durdag, Gulsen Dorgan; Aribogan, Anis; 38131366AIM: The issue of preemptive or preventive use of paracetamol still raises questions in terms of multimodal analgesia in cesarean delivery. A combination of paracetamol and opioid is commonly used for pain management after cesarean delivery. This study aims to compare postoperative pain level and analgesic consumption when using paracetamol at two different perioperative times in cesarean section. MATERIAL AND METHODS: Sixty patients recruited for elective cesarean section under general anesthesia were included in this prospective study. Patients were randomly assigned to receive iv 1 g paracetamol 15 minutes before incision (Group PE) or after delivery of newborn (Group PV). Visual analog scale (VAS) values, 24-hour morphine consumption, additional analgesic requirement, side effects, and patient and surgeons' satisfaction were recorded. RESULTS: Demographic data and hemodynamic values of the patients were similar in both groups. There was no differences between groups in terms of VAS scores at rest and during movement, additional analgesic requirement during the postoperative 1st hour, and 24-hour total morphine consumption. There was no difference in side effects, and patient and surgeon satisfaction scores postoperatively. CONCLUSIONS: Preemptive and preventive use of paracetamol provides the same quality of analgesia and opioid sparing effect without increasing the frequency of adverse effects.Item Reversal of Rocuronium Induced Neuromuscular Block with Sugammadex in Patients Under 2 Years of Age. A Series of 280 Cases(2023) Ozmete, Ozlem; Dardag, Emre; Civi, Soner; 38131376AIM: Neuromuscular muscle relaxants are still indispensable for surgical procedures requiring general anesthesia, and the use of these agents may result in postoperative residual curarization. Sugammadex may offer a distinct advantage to pediatric patients where residual neuromuscular blockade may be poorly tolerated. Sugammadex is approved for use in adults and children over two years. This is the main reason why large-scale studies could not be conducted in the group of patients younger than two years old. This study aimed to evaluate the efficacy and safety of sugammadex for reversing deep rocuronium-induced neuromuscular blockade in children under two years of age. METHODS: Pediatric patients younger than two years of age who underwent neurosurgery under sevoflurane anesthesia were included in the study. Neuromuscular block was achieved by the administration of rocuronium. It was antagonized by the administration of 5 mg/kg sugammadex and evaluated using train-of-four (TOF). Primary outcome measure was the time from sugammadex administration to return of the TOF ratio to 0,9. Postoperative adverse events were also recorded. RESULTS: Two hundred eighty patients (10 day-24 months of age; 3-18 kg) were included in this study. Reversal of deep rocuronium-induced neuromuscular block with sugammadex was rapid in all patients. No residual curarization or recurarization was observed. No adverse events or hypersensitivity reactions were observed after administration of sugammadex. CONCLUSION: Reversal of rocuronium-induced deep neuromuscular block in infants was rapid and safe. Sugammadex provided safe extubation in patients younger than two years of age who had undergone neurosurgery. Research Fund.Item Anesthesia Management of A Patient with Jervell and Lange-Nielsen Syndrome(2015) Bali, Cagla; Ozmete, Ozlem; Ergenoglu, Pinar; Akin, Sule; 0000-0002-6366-941X; 0000-0001-6423-1076; 0000-0001-5845-699X; 0000-0003-2615-1918; 26153335; AAJ-2094-2021; AAI-8790-2021; GON-8465-2022; S-8336-2019; J-5282-2013; AAI-7779-2021Item Anesthesia Management and Sugammadex Experience in A Neonate For Galen Vein Aneurysm(2016) Ozmete, Ozlem; Bali, Cagla; Ergenoglu, Pinar; Andic, Cagatay; Aribogan, Anis; https://orcid.org/0000-0001-5845-699X; https://orcid.org/0000-0003-2615-1918; https://orcid.org/0000-0002-6366-941X; https://orcid.org/0000-0001-8581-8685; https://orcid.org/0000-0002-4419-5693; 27185673; AAI-7779-2021; AAI-8790-2021; GON-8465-2022; AAM-3180-2021; S-8336-2019Item A Patient with Churg-Strauss Syndrome Complicated with Pulmonary Hemoptysis(2016) Bali, Cagla; Ozmete, Ozlem; Ergenoglu, Pinar; Gedikoglu, Murat; Aribogan, Anis; https://orcid.org/0000-0003-2615-1918; https://orcid.org/0000-0001-5845-699X; https://orcid.org/0000-0002-6366-941X; https://orcid.org/0000-0002-9884-3190; https://orcid.org/0000-0002-4419-5693; 27041254; AAI-8790-2021; AAI-7779-2021; GON-8465-2022; S-8336-2019Item A Short View of Chronic Graft-Vs-Host Disease(2016) Bali, Cagla; Ozmete, Ozlem; Ozyilkan, Nesrin Bozdogan; Akin, Sule; Aribogan, Anis; https://orcid.org/0000-0003-2615-1918; https://orcid.org/0000-0001-5845-699X; https://orcid.org/0000-0002-4973-8132; https://orcid.org/0000-0001-6423-1076; https://orcid.org/0000-0002-4419-5693; 27041253; AAI-8790-2021; AAI-7779-2021; AAI-7880-2021; AAJ-2094-2021; S-8336-2019Item Preoperative Paracetamol Improves Post-Cesarean Delivery Pain Management: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial(2016) Ozmete, Ozlem; Bali, Cagla; Cok, Oya Yalcin; Ergenoglu, Pinar; Ozyilkan, Nesrin Bozdogan; Akin, Sule; Kalayci, Hakan; Aribogan, Anis; 0000-0003-3004-2626; 0000-0002-4973-8132; 0000-0002-6366-941X; 0000-0001-5845-699X; 0000-0001-6423-1076; 0000-0003-2615-1918; 0000-0002-4419-5693; 27555133; AAI-8790-2021; S-8336-2019; AAI-7998-2021; J-5282-2013; AAI-7779-2021; AAJ-2094-2021; AAI-7880-2021; GON-8465-2022Study Objective: To evaluate the analgesic effect of preoperative single dose intravenous paracetamol on postoperative pain and analgesic consumption within 24 hours after elective cesarean surgery. Design: Prospective, randomized, double-blind, placebo-controlled clinical trial. Setting: University Teaching Hospital. Patients: American Society of Anesthesiologists (ASA) I and II 60 patients between 18-40 years of age who were scheduled to undergo elective cesarean section. Interventions: Patients were randomized into two groups to receive either intravenous 1 g paracetamol (100 mL) (Group P) or 0.9% NaCl solution (100 mL) (Group C) 15 minutes before the induction of general anesthesia. After delivery of newborn 0.15 mg kg(-1) morphine was administered to all patients in both groups. Postoperative analgesia was provided with patient-controlled intravenous analgesia with morphine in the postoperative period. Measurements: Pain which is the primary outcome measure was assessed at 15th, 30th minutes and 1st, 2nd, 4th, 6th, 12th, 24th hours by the Visual Analogue Scale. Patients' demographics, hemodynamics, Apgar score, additional analgesic requirement, side effects, patients' satisfaction and postoperative total morphine consumption within 24 hours were recorded. Main Results: Median visual analogue scale for pain in Group P was significantly lower compared to Group C at all time points except for the score at 24th h postoperatively (P <.05). Additional analgesic requirement during postoperative first hour was lower in Group P (P <.05). Total morphine consumption was higher in Group C compared with Group P (P <.05). There was no difference between groups with respect to Apgar scores, side effects, and patient satisfaction (P >.05). Conclusions: Preoperative use of single-dose intravenous 1 g paracetamol was found to be effective in reducing the severity of pain and opioid requirements within 24 hours after cesarean section. (C) 2016 Elsevier Inc. All rights reserved.
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