Tıp Fakültesi / Faculty of Medicine
Permanent URI for this collectionhttps://hdl.handle.net/11727/1403
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Item Impact of Sleeve Gastrectomy on Epicardial Fat Tissue and Carotid Intima Media Thickness(2017) Altin, Cihan; Erol, Varlik; Aydin, Elcin; Yilmaz, Mustafa; Sade, Leyla Elif; Gulay, Huseyin; Muderrisoglu, Haldun; 0000-0002-2557-9579; 0000-0003-0907-3647; 0000-0003-3737-8595; 0000-0002-0442-6178; 0000-0002-9635-6313; S-6973-2016; AAI-8276-2021; AAQ-7583-2021; AAJ-6407-2021; AAG-8233-2020Item Epicardial Adipose Tissue Thickness and Carotid Intima-Media Thickness in Hemodialysis Patients(2017) Aydin, Elcin; Altin, Cihan; Sakalhoglu, Onur; Yilmaz, Mustafa; Gezmis, Esin; Sade, Leyla Elif; Muderrisoglu, Haldun; 0000-0002-9635-6313; 0000-0003-0907-3647; 0000-0002-1001-6028; 0000-0003-3737-8595; 28559657; AAG-8233-2020; AAI-8276-2021; AAE-8301-2021; AAQ-7583-2021; HGC-1839-2022Background: It is well-known that cardiovascular risk and all-cause mortality is increased in hemodialysis patients. Epicardial fat thickness (EFT), which reflects visceral adiposity, has been suggested as a new cardiometabolic risk factor. The purpose of this study was to investigate EFT in hemodialysis patients. Methods: A total of 144 consecutive patients (60 hemodialysis patients and 84 controls) were enrolled into the study, and patients with diabetes mellitus and cardiovascular diseases (CVD) were excluded. EFT was measured on the free wall of the right ventricle at end-diastole from the parasternal long-axis view by standard transthorasic 2D echocardiography. Results: The groups were similar in terms of sex distribution, age, blood pressure, heart rate and frequencies of CAD risk factors including smoking status, family history of CAD and hypertension. There were no significant differences between the hemodialysis patients and controls in 2D echocardiographic parameters, including ejection fraction and biochemical parameters except low-density lipoprotein, high-density lipoprotein and c-reactive protein. Despite having lower body mass index, EFT levels were significantly higher in hemodialysis patients compared to the controls (8.0 +/- 2.2 mm vs. 5.8 +/- 1.9 mm; p < 0.01). In multivariate linear regression analysis we determined that hemodialysis patient status was found to be an independent predictor for both EFT ((3 = 0. 700, p = 0.014) and carotid intima-media thickness (CIMT, beta = 0. 614, p = 0.047). Conclusions: Hemodialysis patients are independently associated with high EFT and CIMT.Item MRI Perfusion Findings in Acute Cerebral Infarction and Perfusion Parameters Used in the Evaluation Penumbra(2016) Aydin, Elcin; Calli, Mehmet Cem; Uncu, Gulgun; Sirin, Hadiye; 0000-0003-0907-3647; AAI-8276-2021; ABB-5268-2020Objective: In this trial, our objective is to emphasize the importance of the magnetic resonance perfusion in the early diagnosis and therapy of cerebral ischemia and to discuss the reliable perfusion maps for identifying peunumbra. Material and Methods: Participants of this trial have been selected among patients who applied to the Ege University Radiology Department with cerebrovascular event and had an acute infarct which was diagnosed by MR. Among 20 of these patients, dynamic suceptibilite contrast (DSC) imaging with 1.5 T MR Magnetom Vision, Siemens, Erlangen, Germany) was performed with standart head bandage. At contrast perfusion imaging a bolus of 0.1 mmol/kg Gadolinium was injected by a speed of 3ml/sec. Multishot echoplanar imaging (EPI) imaging was performed for determining the changes at T2* relaxation time. The DSC perfusion parametres and function maps were obtained and eveluated at the postprocessing stage. The precence of penumbra was diagnosed by comparing the perfusion maps with difusion images. Results: Seventy nine percent of the patients had a lesser degree of cerebral blood volume (CBV) and cerebral blood flow (CBF) at the infarcted area then contrary hemisphere but at 11% of the patients there was no difference with contrary hemisphere. Five percent of the patients had remarkable blood flow increase. This was thought to be cause of the important role of the brain's autoregulation function. There was an expected delay at 90% of the patients in contrast passing time and peak time. By comparing the diffusion with perfusion maps, the penumbra was diagnosed at 4 patients by mean transit time (MTT) and time to pic (TTP) maps, at 3 patients by CBF map and at 1 patient by CBV map. Conclusion: The early diagnosis and evaluation of acute ischemic stroke, improves the patients' quality of life. The perfusion MR has a pathfinder role in the diagnosis and therapy of acute infarct. Penumbra is a dynamic tissue and the treatment after the early identifying of the penumbra, defines the patients prognosis. The most reliable perfusion map for determining the penumbra is controversial and much more trials are need to be done about this subject. According to recent trials and our investigation, the penumbra area seems to be larger which is determined by using the TTP and MTT maps. This condition is due to the exaggerated appearance of the ischemic penumbra secondary to the benign oligemia with severe arterial occlusive changes. In the literature the most reliable maps are relative cerebral blood volume (rCBV) and relative cerebral blood flow (rCBF) maps for demonstrating the last infarct area and our findings are also in the same way.Item Brain Infarction in A Young Patient with Buerger's Disease - A Case of Cerebral Thromboangiitis Obliterans(2016) Aydin, Elcin; Cinar, Celal; Bozkaya, Halil; Oran, Ismail; 0000-0003-0907-3647; AAI-8276-2021; ABG-8329-2020Buerger's disease (BD) or thromboangiitis obliterans is a vasculitis that most commonly affects the small and medium-sized arteries and veins in the extremities. 1 It is most frequently seen in the young men who smoke and is associated with low socioeconomic status. BD is diagnosed on the basis of the clinical findings; the pathogenesis is not completely be understood. 1-4 In this report, we aim to present the clinical, magnetic resonance imaging (MRI) and angiographic findings of a 30-year-old man with ischemic stroke as a rare complication of BD.Item Primary breast tuberculosis: imaging findings of a rare disease(2021) Baykan, Ali H.; Sayiner, Hakan S.; Inan, Ibrahim; Aydin, Elcin; Erturk, Sukru M.; 0000-0003-0907-3647; 33587199; AAI-8276-2021Breast tuberculosis is a rare form of extrapulmonary tuberculosis which tends to affect females of reproductive age, and is much rarer in males, postmenopausal women, and pre-pubescent girls. It is difficult to diagnose because it can mimic benign conditions such as a fibroadenoma, as well as malignant diseases like a carcinoma. It is also particularly difficult to distinguish breast tuberculosis from granulomatous mastitis, so other possible diagnoses should be ruled out first. The diagnosis of breast tuberculosis has three essential pillars: clinical examination, radiological evaluations, and histopathological sampling. Radiological evaluations are not only critical in diagnosis but are also important in the planning of the treatment and during the follow-up. This paper aims to review the imaging findings and the differential diagnosis of breast tuberculosis.Item MRI evaluation of progressive supranuclear palsy: differentiation from Parkinson's disease and multiple system atrophy(2019) Eraslan, Cenk; Acaer, Ahmet; Guneyli, Serkan; Akyuz, Esra; Aydin, Elcin; Colakoglu, Zafer; Kitis, Omer; Calli, Mehmet Cem; 30373485Objectives: To evaluate the magnetic resonance imaging (MRI)-derived parameters in differentiation of patients with progressive supranuclear palsy (PSP) from patients with Parkinson's disease (PD), multiple system atrophy (MSA), and control subjects was aimed. Methods: Thirty-three patients [mean age, 65.21 +/- 4.75 years; PSP (n = 9), MSA (n = 8), PD (n = 6), and control subjects (n = 10)] who have undergone cranial MRI were included in this retrospective study. MRI-derived parameters including areas of midbrain and pons, midbrain area-to-pons area (M/P) ratio, widths of middle cerebellar peduncle (MCP) and superior cerebellar peduncle (SCP), MCP/SCP ratio, magnetic resonance parkinsonism index (MRPI), cerebral interpeduncular angle, and length of midbrain tegmentum were compared in patients with PSP, PD, MSA, and control subjects through the analysis of variance and Kruskal-Wallis tests with Bonferroni correction and Mann-Whitney U test. Results: The length of midbrain tegmentum, midbrain area, SCP, and M/P ratio were found to be lower, while cerebral interpeduncular angle and MRPI were higher in patients with PSP. Pons area, MCP width, and MCP/SCP ratio were found to be lower in patients with MSA. For PSP, cerebral interpeduncular angle has a sensitivity of 100% and specifity of 90%, and MRPI had a sensitivity of 88.9% and specifity of 100% for PSP. Discussion: Several MRI-derived parameters can be used in differentiation of patients with PSP from patients with PD, MSA and control subjects. The cerebral interpeduncular angle and MRPI, which demonstrated higher values in patients with PSP, were more significant for PSP than the other parameters.Item Assessment of Subclinical Atherosclerosis in Vitamin D Deficiency(2019) Aydin, Elcin; Altin, Cihan; Soylev, Gozde Ozcan; Tekindal, Mustafa Agah; Agildere, Muhtesem; 30300321; AAB-5802-2020Purpose Patients with vitamin D deficiency (VDD) have potential to have increased cardiovascular morbidity and mortality. In this study, we aimed to discover the findings of early atherosclerosis in patients with VDD by measuring carotid intima-media thickness (CIMT) and epicardial fat thickness (EFT). Materials and Methods The study population includes 52 patients with VDD (n = 30 [57% female], mean +/- SD age 54.28 +/- 8.77 years, mean +/- SD serum 25-hydroxyvitamin D (25 [OH] D) 11 +/- 2.4 ng/mL) and 82 participants for control group (n = 52 [63.4% female], mean +/- SD age 56.40 +/- 7.90 years, mean +/- SD serum (25 [OH] D) 53 +/- 4.2 ng/mL) who have no cardiovascular disease. Carotid intima-media thickness was assessed by using ultrasonography, and EFT was measured on the free wall of the right ventricle at end diastole from the parasternal long-axis views by standard transthoracic 2-dimensional echocardiography. Results Both CIMT and EFT were significantly higher in patients with VDD compared with controls (0.75 +/- 0.16 mm vs 0.68 +/- 0.21 mm, P < 0.05, and 0.66 +/- 0.15 cm vs 0.56 +/- 0.15 cm, P < 0.001). Conclusions Patients with VDD seem to have increased CIMT and EFT, which are predictors of atherosclerotic process. Further studies are needed to confirm these results.Item One of the Rare Causes of Acute Abdomen Leading to Subileus: Jejunal Diverticulitis(2016) Aydin, Elcin; Yerli, Hasan; Avci, Tevfik; Yilmaz, Tugbahan; Gulay, Huseyin; 27308082Background: Jejunal diverticulitis is one of the rare causes of acute abdomen generally seen in the elderly. Jejunal diverticulosis was defined as the herniation of the mucosa and the submucosa from the inside of the muscular layer of the bowel wall on the mesenteric side of the intestine. Case Report: We presented the intraoperative and pathological findings of a 69-year-old male patient who had presented with complaints about abdominal pain, nausea, and vomiting and been operated upon due to subileus and peritonitis induced by large-sized jejunal diverticulitis, along with his computed tomography (CT) findings. Conclusion: Jejunal diverticulitis is uncommon and may be a disease which might be difficult to diagnose when it develops on the basis of the large-sized diverticula resembling intestinal ansae. To the best of our knowledge, the computed tomography and intraoperative findings of a case in which partial resection is applied to the jejunum due to subileus have not been previously presented in the literature.Item Temporal Lobe Parenchyma Herniation into the Transverse Sinus: MRI Findings in a Case(2016) Aydin, Elcin; Yerli, Hasan; Gezmis, Esin; 0000-0002-1001-6028; 0000-0003-2463-1758; 0000-0003-0907-3647; 30151437; AAE-8301-2021; AAK-9572-2021; AAI-8276-2021Brain parenchyma herniation into dural venous sinus which is a uncommon entity, can cause dural venous sinus filling and simulate sinus thrombosis and other pathologies. It is isointense to brain parenchyma on all sequences by magnetic resonance imaging, surrounded by a cerebrospinal fluid rim and is seen to be contiguous with brain tissue on images. We report a rare case with spontaneous occult herniation of temporal lobe tissue into the left transverse sinus that may associated with headache.Item Vascular Leiomyoma Presenting as Anterior Knee Pain (Case Report)(2016) Aydin, Elcin; Coban, Gokcen; Coskunoglu, Esra Zeynep; Tukenmez, Mehmet; 0000-0003-0907-3647; 0000-0003-4824-4138; 30151458; AAI-8276-2021; AAJ-6774-2021Vascular leiomyomas or angioleiomyomas are rare benign solitary smooth muscle tumors that origin usually in the extremities. Most of these tumors are composed of venous vessels. Here in, we report a rare case of subcutaneous vascular leiomyoma of the right knee of a 38 year old woman who was presented with recurrent anterior right knee pain and soft tissue swelling. Clinical findings, magnetic resonance imaging and histopathologic findings of the tumor is discussed. Leiomyomas are not mostly considered in the differential diagnosis by radiologist due to its rarity. Typical imaging and clinical findings of a tumor is an important clue for an accurate and early diagnosis.