Başkent Üniversitesi Yayınları

Permanent URI for this communityhttps://hdl.handle.net/11727/13092

Browse

Subject: search.filters.subject.Egyptian

Search Results

Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    Proteinuria Among Renal Transplant Patients and Its Relation to Hepatitis C Virus and Graft Outcome: A Single Center Experience
    (Başkent Üniversitesi, 2010-06) Sabry, Alaa
    Objectives: Chronic hepatitis C virus has been associated with glomerular disease in native and transplanted kidneys. Reports suggest that hepatitis C virus-infected renal recipients may develop de novo glomerulonephritis. We evaluated the presence of hepatitis C virus at transplant, the occurrence of proteinuria in Egyptian renal transplant patients, and its possible link with graft survival. Materials and Methods: Three hundred seventeen patients with end-stage renal disease receiving transplants in Mansoura Urology and Nephrology Center were retrospectively evaluated between 2000 and 2003. Their sera were assayed for anti-hepatitis C virus-antibodies at transplant. The relation between hepatitis C virus and development of posttransplant proteinuria was evaluated, along with possible effects of proteinuria on long-term graft survival. Results: Two hundred seventy-three recipients fulfilled the inclusion criteria, 169 were positive and 104 were negative for hepatitis C virus-antibodies by ELISA. Mean duration of posttransplant follow-up was 87.73 ± 26.79 and 84.29 ± 28.55 months for both groups. Groups were comparable regarding the incidence and quantity of hepatitis C virus-positive patients and 0.4 grams/day (P = .09 of proteinuria). In both hepatitis C virus-positive and negative groups, those with nephrotic range proteinuria showed worse graft survival (P = .001) and higher frequency of chronic allograft nephropathy (P = .05) compared with nonproteinuric patients. Conclusions: There is a high prevalence of hepatitis C virus in our end-stage renal disease patients awaiting renal transplant. The incidence and quantity of proteinuria is similar in both hepatitis C virus-positive and hepatitis C virus-negative transplant recipients. Nephrotic range proteinuria is associated significantly with a higher incidence of chronic allograft nephropathy. Independent from serology, it is associated with poorer graft outcome.
  • No Thumbnail Available
    Item
    Geriatric Burns in Ain Shams University Burn Unit: A Comparative Epidemiological Study
    (Başkent Üniversitesi, 2023-09) Amr Mabrouk; Mai Raafat Hammad; Adel Mabrouk; Mohamed Samir Badawy
    ABSTRACT OBJECTIVES: In Egypt, the geriatric burn population faces unique challenges, and understanding the problem is crucial for effective management. Here, we examined the epidemiology and outcomes of geriatric patients presenting to the Ain Shams University burn unit, over a period from January 2019 to July 2022. MATERIALS AND METHODS: This prospective study investigated all patients older than 60 years of age who presented to the Ain Shams University Burn Unit from January 2019 to July 2022; we compared findings with our previous work published 20 years ago, in which we examined the same population from May 1995 to October 2001. The parameters investigated were patient characteristics/demographics, seasonal and day/hour variations in burn incidence, place of residence and site where burn injury occurred, type and extent of burns, treatment and hospital stay, and morbidity/mortality rates. RESULTS: Despite the number of geriatric patients presenting to our burn unit being higher, a lower percentage required admission. Early excision and grafting were performed with a higher frequency, which may be attributed to the fewer patients with chronic illnesses. There was a reduction in both morbidity and mortality. CONCLUSIONS: Substantial changes have been made in recent years in the approach to geriatric burns, including with prevention strategies and early intervention, which have led to a reduction in both morbidity and mortality among our patients. Multidisciplinary care, involving a team of health care professionals, including burn and plastic surgeons, geriatricians, and occupational therapists, is necessary to address the complex needs of this population.