Fakülteler / Faculties
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Item Farmasötik mikrobiyoloji uygulamaları(2025) Abbasoğlu, UfukItem İletişimin Özneleri(Başkent Üniversitesi Geliştirme Vakfı İktisadi İşletmesi, 2025-06) Erdem, Beste Nigar; Akcan, Burçe; Çağlıyan, Çağdaş Emrah; Akçay, Ebru; Temizer, Eylem; Canlı, Kübra; Ünal Çınar,Reyhan; Ay, Semra; Dikkol Akçay, Selver; Bal, Sevil; Kına, Sezer A.; Özcan, S. YankıItem Risk Assessment and Selection of Plant Protection Products to be Used in Integrated Pest Management Programmes(JOURNAL OF TEKIRDAG AGRICULTURE FACULTY-TEKIRDAG ZIRAAT FAKULTESI DERGISI, 2024-05-01) Erdogan, CemIn Turkiye, it is important to carry out agricultural production in a sustainable manner by protecting biodiversity. Our country's agricultural sector has various problems in production, some of which have become chronic. There are many problems affecting agricultural production and productivity such as decreasing arable agricultural areas, increasing food demand, young generation moving away from agriculture, input costs, rural development, prevalence of small family farming and consequently fragmented land structure and climate change. One of the reasons affecting productivity in production is diseases, pests and weeds in agricultural production. The way of sustainable agricultural production by protecting biological diversity is through the implementation of Integrated Pest Management (IPM). In Integrated Pest Management, it is essential to use all control methods against agricultural pests in harmony, and biological, biotechnical and cultural measures are prioritised. As a last resort, the application of Plant Protection Products (PPPs) is desired. For this reason, the PPS to be used should not be harmful to human health, should not cause environmental pollution, should not adversely affect parasitoids, predators, pollinators and should not cause residues in the products. In other words, it is essential that the application of PPPs should not be carried out randomly and unconsciously, but in a sustainable manner based on reason, science, knowledge and in a way that will help the conservation of biological diversity. In the selection of PPPs to be used in Integrated Pest Management, risk assessments are made by considering the effects of active substances on mammals, fish, non-target organisms (parasitoids, predators) and honey bees and their persistence in soil in order to reveal the risks that may occur in terms of human and environmental health, and priority is given to PPPs such as biologics and insect growth regulators. As a result of the risk assessment studies carried out, a total of 734 PPPs, including 495 active substances, 204 mixtures, 13 biological preparations, 21 biological control agents and 1 safener, were examined and the appropriate ones were presented to the service of our producers and our country's agriculture in the integrated control technical instructions.Item Construction of the Atmosphere in Vahîd Mahtûmî's Shehrengiz Named Lâlezâr (Yenişehr-i Fenâr)(FOLKLOR/EDEBIYAT-FOLKLORE/LITERATURE, 2024-05-31) Aytac, AsliShehrengiz can be defined as a poetic genre that presents the beauties of a neighborhood, who are famous in various arts and professions, with the elements of social life and local beauties of that neighborhood, with vivid descriptions and colorful praises. Shehrengiz texts have an important place in terms of not only recording the famous tradesmen, but also shedding light on the socio-cultural structure of the period they belong to, containing information about social and economic life, and reflecting features of daily spoken language. When evaluated together with the poet's style, shehrengiz works should be considered as socio-cultural keys that involve many clues in the context of the structure of the society and the historical texture of the place or places in question. In Turkish literature, the shehrengiz type, which was mostly written in masnavi verse, began giving examples at the beginning of the 16th century and continued until the late 18th century. The text, which is the subject of the study, is the L & aacute;lez & aacute;r (Yeni ehr-i Fen & aacute;r) shehrengiz consisting of 524 couplets, in which Vah & icirc;d Maht & ucirc;m & icirc;, one of the 18th century poets, describes the characteristics of the city of Yeni ehir, which is located in the borders of Greece today. Based on the text written in the form of masnavi , the places where the poet gave place to his description and the atmosphere created from these places were evaluated and the literary features of the expression were emphasized. The aim of the study is to illuminate the image of the city in the period and to reveal the effects of the places whose atmosphere is reflected on the mood of the people and social life by reading the characteristics of the places mentioned from the style of Maht & ucirc;m & icirc;, who successfully reflected the folk language and daily life conditions into poetry in the 18th century.Item Peer Support In Mental Health Services: Familiar And Brand New(KLINIK PSIKIYATRI DERGISI-TURKISH JOURNAL OF CLINICAL PSYCHIATRY, 2024-06-23) Ozden, Seda Attepe; Bekiroglu, Seval; Soygur, Arif HaldunIn recent years, it is widely accepted that the experiences of individuals who benefit from mental health services are reflected in the treatment and rehabilitation process in the field of mental health. Transferring the experiences of individuals to the treatment process has put the concept of peer support at the forefront. Peer support means that individuals with personal experience in mental health use this experiential expertise to help other individuals with mental health problems during the recovery process. Peer support is a system that allows individuals with mental health problems to partner, feel understood by each other, and build emotional intimacy. It is known that peer support contributes in a positive direction to both those who provide peer support and those who benefit from this support Peer support is handled in a wide framework ranging from individual friendship relations to employment of support service providers in institutions. In many countries, peer support practices are used as a component of mental health services. It is recommended to use peer support during treatment throughout the world. This article discusses the birth, definition, types and contributions that the concept of peer support can make to the healing process.Item Machine Learning-Based Weather Prediction With Radiosonde Observations(JOURNAL OF THE FACULTY OF ENGINEERING AND ARCHITECTURE OF GAZI UNIVERSITY, 2024-07-16) Gogen, Eralp; Guney, SeldaFrom the past to the present, weather forecasting holds significant importance for humanity. The precise execution of weather forecasting enables the implementation of precautions against natural disasters such as floods, tsunamis, etc., thereby minimizing the adverse effects that may arise. In this study, weather prediction is conducted using Radiosonde data. Within this prediction, estimations for both the highest and lowest temperatures are made employing machine learning algorithms. Unlike previous temperature prediction studies in the literature, a three-year dataset of Radiosonde observations is utilized. This dataset, measured at intervals of 1mbar up to an altitude of 40 km from the ground, allows for a more accurate modeling of the atmosphere compared to other studies in the literature. In this model, predictions for the highest and lowest temperatures for the next day are made. In this stage, the effects of normalization, feature extraction, or selection on the results are analyzed, and the most suitable model for prediction is determined. The software, implemented in the MATLAB environment, compares different regression methods. As a result of these analyses, utilizing the Gaussian Process Regression (GPR) method, the highest temperature prediction for the next day is achieved with the highest accuracy, with a mean square root deviation of 1.2. Using the same method, the lowest temperature prediction is made with a mean square root deviation ratio of 2.4. The results indicate more successful temperature predictions compared to studies in the literature.Item Optimization Of Drilling Process Parameters For Additive Manufacturing Parts Produced Using The Fdm Method(JOURNAL OF THE FACULTY OF ENGINEERING AND ARCHITECTURE OF GAZI UNIVERSITY, 2024-09-15) Zorer, Ezgi Selen; Ayhan, Emre; Yurdakul, Mustafa; Ic, Yusuf TanselThe melt deposition modeling method (FDM) is one of the increasingly widespread additive manufacturing methods, known as 3D printing, based on the layered assembly of material filaments. However, it is seen that the parts produced with FDM in the aviation industry do not have the desired dimensional and geometric tolerance values. For this reason, different manufacturing methods are used to bring the parts produced by the FDM method to the desired tolerance values. In this study, experiments were carried out to improve the tolerance values of the holes on the plates made of polycarbonate material, which is widely used in prototyping and production tools (welding, drilling, fixing) with FDM, and the optimum processing parameters were determined using the integrated design of experiment and TOPSIS methods. According to the obtained results, the optimum drilling parameters for the plate without pre-drilling case could be obtained by selecting HSS as the drill material, using cutting fluid, and setting the feed rate to 390.9091 mm/min and the spindle speed to 1000 rpm. For the pre-drilled plate, the optimum drilling parameters were again obtained by selecting the drill material HSS, using cutting fluid and applying the feed rate to 369.6970 mm/min and the spindle speed to 781.8182 rpm.Item Analyzing Ahmet Umit's Bir Ask Masalı Through Campbell's Monomyth Theory(FOLKLOR/EDEBIYAT-FOLKLORE/LITERATURE, 2024-11-26) Gulveren, Ozlem BayFairy tales, which have survived from generation to generation in oral culture and have been reintroduced with the transition to written culture, continue to hold their place and importance in contemporary literature. Today's writers create modern narratives, which we can call literary fairy tales- though definitions may vary-, by utilizing the form and content characteristics of fairy tales and the possibilities they offer. In this text-immanent study, I examined Ahmet Omit's work Bir A & scedil;k Masal & imath; as an example of contemporary narratives, due to its inclusion of elements of fairy tales and mythology, within the framework of Joseph Campbell's Monomyth Theory, which he outlined in his work The Hero with a Thousand Faces and can be summarized under the headings of "Departure-Initiation-Return". In the article, I first provided brief information about fairy tales, traditional folk tales, and literary fairy tales, and then attempted to summarize Campbell's Monomyth Theory in connection with Jung's concept of "archetype". In the analysis section, I evaluated the content of the tale under the headings of "Departure", "Initiation", and "Return" respectively. As a result of my examination, I found that the enchanting narrative created by Ahmet Omit aligns with the main headings of Campbell's Monomyth Theory but does not fully meet some subheadings and shifts others to different stages of the cycle. In the modern tale I examined, I find it noteworthy that the cycle Campbell presented is not completed, and the heroes fail to achieve any subheading of the return stage. The author chose to make each of the heroes, who embarked on a journey in search of true love and completed the initial stages of the cycle, fail in the final stages for the same reason. The characters who have not managed to detach themselves from their egos cannot be expected to "become heroes." It would not be inaccurate to assert that the author has created anti-heroes, divergent from the conventional heroes found in traditional fairy tales. In this modern tale, the story of traditional fairy tale heroes who return home with the ultimate reward after maturing has been replaced by the story of heroes who, moving in the opposite direction, succumb to their ambitions and will never return home.Item Sodyum glukoz ortak taşıyıcı-2 inhibitör tedavisi kullanan tip-2 diyabetes mellitus hastalarından oluşan bir retrospektif kohortta glomerüler filtrasyon hızının ürik asit metabolizmasına etkisi(Başkent Üniversitesi Tıp Fakültesi, 2024) Emre, Varoğlu; Altuğ, KurtSodyum glukoz ortak taşıyıcı-2 (SGLT-2) inhibitörleri Tip-2 Diyabetes Mellitus (Tip-2 DM) tedavisinde kullanılan oral antidiyabetik ajanlardır. SGLT-2 inhibitörlerinin üriner glukoz atılımıyla etkili glisemik kontrol sağlamasının yanı sıra diyabet hastalığın prognozuna etkili olan serum ürik asit (ÜA) düzeyini düşürdüğü bilinmektedir. Çalışmanın amacı SGLT-2 inhibitör tedavisi alan Tip-2 DM hastalarındaki farklı glomerüler filtrasyon hızının (GFH) serum ÜA düzey değişimine etkisini incelemektir. 1 Ocak 2017- 30 Eylül 2022 tarihleri arasında Başkent Üniversitesi Ankara Hastanesi Endokrin ve Metabolizma Hastalıkları Polikliniği’ne başvuran, Tip-2 DM tanısı almış ve SGLT-2 inhibitör tedavi raporu çıkarılıp reçetesi yazılan 3004 hasta çalışmanın evrenini oluşturmaktadır. Hastanın kesintisiz SGLT-2 inhibitörü kullanmaması, 3.ay ve/veya 12.ay takip kontrollerine gelmemesi, serum ÜA düzeyini etkileyen ilaçlar kullanması ve gut hastalığı tedavisi alıyor olması dışlama kriterleriydi. Hastane Medikal Bilgi Sistemi üzerinden çalışmanın örneklemini oluşturan 410 hastanın, SGLT-2 inhibitör ilaç raporu almadan önce ölçülen serum HbA1C, açlık kan şekeri (AKŞ), kreatinin, yüksek dansiteli lipoprotein (HDL), düşük dansiteli lipoprotein (LDL), trigliserit, ÜA ve idrar glukoz düzeyleri ile SGLT- 2 inhibitör tedavisi altındaki 3.ay ve 12.ayda bakılan değerleri karşılaştırılmıştır. Böbrek Hastalıkları Küresel Sonuçların İyileştirilmesi Vakfı’na (KDIGO) göre hastalar 3 gruba (GFH ≥90, 60-89, 30-59 ml/dk/1,73m2) ayrılmış ve SGLT-2 inhibitörlerinin GFH’a göre ürik asit düzeyine etkisi incelenmiştir. Çalışma grubu 227 erkek, 183 kadın hastadan oluşmaktaydı. Hastaların yaş ortalamaları 59,1±11,55/yıl idi. Hastaların SGLT-2 inhibitör tedavi öncesi ölçülen serum HbA1C, AKŞ, kreatinin, LDL, trigliserit, ÜA değerleri tedavi altında azalırken; HDL ve idrar glukoz düzeyleri ise tedavi altında arttığı saptandı. GFH düzeyi 30-59 ml/dk/1,73m2 arasında olan hastalarda ilaç öncesi (6,35±1,31), ilaç tedavisi 3.ay (6,02±1,05) ve ilaç tedavisi 12.ay (5,97±1,21) takiplerinde serum ÜA değerleri arasında anlamlı fark bulunmadı (p=0,368). Çalışma, SGLT-2 inhibitörlerinin serum ÜA düzeyine olan etkisinin GFH’a göre farklılık gösterdiğini saptamıştır. SGLT-2 inhibitörlerinin, yalnızca antidiyabetik ilaç olmadıkları, bu ilaçların lipit profili ve GFH’ı korunmuş hastalarda serum ürik asit düzeyine olan etkileri ile hiperlipidemi ve hiperürisemi ilişkili hastalıklara karşı da koruyucu rolü olabileceğini göstermiştir. Sodium glucose cotransporter-2 (SGLT-2) inhibitors are oral antidiabetic agents used in the treatment of type-2 diabetes mellitus (type-2 DM). SGLT-2 inhibitors are known to provide effective glycemic control through urinary glucose excretion, as well as to reduce serum uric acid (UA) levels, which affect the prognosis of diabetes. The aim of the study was to investigate the effect of different glomerular filtration rates (GFR) on serum UA level changes in Type-2 DM patients receiving SGLT-2 inhibitor therapy. Between January 1, 2017 and September 30, 2022, 3004 patients who were admitted to the Endocrine and Metabolic Diseases Outpatient Clinic of Başkent University Ankara Hospital, diagnosed with Type-2 DM and prescribed SGLT-2 inhibitor treatment reports and prescriptions constituted the study population. Exclusion criteria were that the patient was not taking SGLT2 inhibitors continuously, did not attend the 3rd month and/or 12th month follow-up visits, was taking medications that affect serum UA levels, and was being treated for gout. Serum HbA1C, fasting blood glucose (FBG), creatinine, high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglyceride, UA and urine glucose levels measured before receiving SGLT-2 inhibitor medication report were compared with the values measured at 3 months and 12 months under SGLT-2 inhibitor treatment in 410 patients who constituted the sample of the study through the Hospital Medical Information System. Patients were divided into 3 groups (GFR ≥90, 60-89, 30-59 ml/min/1.73m2) according to the Kidney Disease Foundation for Improving Global Outcomes (KDIGO) and the effect of SGLT-2 inhibitors on uric acid levels according to GFR was analyzed. The study group consisted of 227 male and 183 female patients. The mean age of the patients was 59.1±11.55/year. Serum HbA1C, FBG, creatinine, LDL, triglycerides, and UA levels decreased, whereas HDL and urine glucose levels increased under drug treatment compared to before SGLT-2 inhibitor treatment. In patients with GFR between 30-59 ml/min/1.73m2, no significant difference was found between serum UA values at pre-drug (6.35±1.31), 3rd month under drug therapy (6.02±1.05) and 12th month under drug therapy (5.97±1.21)(p=0.368). The study found that the effect of SGLT-2 inhibitors on serum UA levels differed according to GFR. The study showed that SGLT-2 inhibitors are not only antidiabetic drugs, but may also have a protective role against hyperlipidemia and hyperuricemia-related diseases with their effects on lipid profile and serum uric acid levels in patients with preserved GFR.Item Tıkınırcasına yeme bozukluğu tarama anketinin ((beds-7) binge-eating disorder screener) türkçe geçerlilik ve güvenilirlik çalışması(Başkent Üniversitesi Tıp Fakültesi, 2024) Caner, Aker; Altuğ, KurtTıkınırcasına Yeme Bozukluğu (TYB); tıbbi, psikolojik ve sosyal problemlere neden olan ve yaşam kalitesini düşüren bir yeme bozukluğudur.DSM-5’te kendi başına ayrı bir bozukluk olarak tanımlanan TYB’nin görülme sıklığı giderek artmaktadır. Çalışmanın amacı, TYB olan bireyleri belirlemek için kullanılan BEDS-7 (Binge Eating Disorder Screener-7) ölçeğinin Türkçe çevirisini yapmak ve çevrilen formun psikometrik özelliklerini incelemektir. Katılımcıların yaş, cinsiyet, boy, kilo, meslek, medeni durum ve ruhsal hastalık öyküsü gibi sosyodemografik bilgileri toplanmıştır. Ayrıca, katılımcılar tarafından Beck Depresyon Ölçeği (BDÖ) ve Beck Anksiyete Ölçeği (BAÖ) doldurulmuştur. TYB tanısında kullanılan yarı yapılandırılmış bir görüşme olan EDA-5 (Eating Disorder Assessment for DSM-5) testi uygulanmıştır. BEDS-7 ölçeği, son üç ayda aşırı yeme epizodu yaşanıp yaşanmadığını ve bu epizotlar sırasında yaşanan duygusal durumları sorgulayan yedi sorudan oluşmaktadır. İlk iki soru evet ve hayır seçenekli olup, ilk soruya hayır yanıtı verilmesi durumunda test sonlandırılmaktadır. İkinci soruya evet yanıtı verilmesi halinde diğer sorular yanıtlanmaktadır. Sorular, aşırı yeme epizotları esnasında yaşanan stres, kontrol kaybı, aç olmadığı halde yeme, utanç ve suçluluk hissi gibi duyguları sorgulamaktadır. Çalışmanın bulgularına göre, BEDS-7’nin Türkçe versiyonunun anlamlı düzeyde geçerlilik ve güvenilirlik sağladığı saptanmıştır. Ölçeğin faktör yapısını incelemek için gerçekleştirilen açımlayıcı faktör analizi (AFA) neticesinde, iki boyuttan oluşan bir yapı ortaya konmuştur. Yedinci madde, tüm katılımcılar tarafından aynı şekilde yanıtlandığı için herhangi bir boyuta dahil edilmemiştir. Ölçeğin altı maddesinin Cronbach alfa katsayısı 0,693 olarak bulunmuştur. Doğrulayıcı faktör analizi (DFA) kullanılarak ilgili değişkenler arasındaki korelasyonlar incelenmiş ve ölçeğin yapısal geçerliliği desteklenmiştir. Çalışmanın sonuçlarına göre, BEDS-7’nin depresyon ve anksiyete semptomlarını değerlendiren BDÖ ve BAÖ ile anlamlı düzeyde pozitif ilişkili olduğu görülmüştür. BEDS-7 toplam puanı; BDÖ toplam puanıyla %49,6, BAÖ toplam puanıyla %58,9 oranında pozitif ilişkili bulunmuştur. Sonuç olarak, bu çalışma BEDS-7’nin Türkçe versiyonunun geçerlilik ve güvenilirliğini ortaya koymuştur. BEDS-7’nin Türkçe versiyonunun, TYB taramasında kullanılabilir bir ölçek olarak klinik ve araştırma ortamlarında özellikle de birinci basamakta kullanılabileceği sonucuna varılmıştır. Binge Eating Disorder (BED) is an eating disorder that leads to medical, psychological and social problems and negatively affects quality of life. The prevalence of BED, which is defined as a separate disorder in DSM-5, is gradually increasing. The aim of this study is to translate the BEDS-7 (Binge Eating Disorder Screener-7) scale, which is used to identify individuals with BED, into Turkish and to examine the psychometric properties of the translated questionnaire. Sociodemographic information such as age, gender, height, weight, occupation, marital status and history of mental illness were collected. In addition, Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) were completed by the participants. The EDA-5 (Eating Disorder Assessment for DSM-5), a semi-structured interview used in the diagnosis of BED, was administered. The BEDS-7 scale consists of seven questions examining whether binge eating episodes have been experienced in the last three months and the emotional states experienced during these episodes. The first two questions have yes and no options, and the test is terminated if the first question is answered no. If the response to the second question is yes, the other questions will be answered. The questions investigate emotions experienced during binge eating episodes such as stress, loss of control, eating when not hungry, shame and guilt. According to the findings of the study, it was determined that the Turkish version of the BEDS-7 provided significant validity and reliability. Exploratory factor analysis (EFA) conducted to determine the factor structure of the scale revealed a two-dimensional structure. The seventh item was not included in any dimension because it was answered in the same way by all participants. Cronbach's alpha coefficient of the six items of the scale was found to be 0.693. Using confirmatory factor analysis (CFA), the correlations between the relevant variables were examined and the structural validity of the scale was supported. According to the results of the study, the BEDS-7 was found to be significantly positively correlated with the BDI and BAI, which assess depression and anxiety symptoms. BEDS-7 total score was positively correlated with BDI total score by 49.6% and with BAI total score by 58.9%. In conclusion, this study demonstrated the validity and reliability of the Turkish version of the BEDS-7. It was concluded that the Turkish version of BEDS-7 can be used in clinical and research settings, especially in primary care, as a usable scale in BED screening.