Fakülteler / Faculties
Permanent URI for this communityhttps://hdl.handle.net/11727/1395
Browse
8277 results
Search Results
Item Comprehensive Data Analysis Of White Blood Cells With Classification And Segmentation By Using Deep Learning Approaches(Başkent Üniversitesi Mühendislik Fakültesi, 2024-04-05) Ozcan, Seyma Nur; Uyar, Tansel; Karayegen, GokayDeep learning approaches have frequently been used in the classification and segmentation of human peripheral blood cells. The common feature of previous studies was that they used more than one dataset, but used them separately. No study has been found that combines more than two datasets to use together. In classification, five types of white blood cells were identified by using a mixture of four different datasets. In segmentation, four types of white blood cells were determined, and three different neural networks, including CNN (Convolutional Neural Network), UNet and SegNet, were applied. The classification results of the presented study were compared with those of related studies. The balanced accuracy was 98.03%, and the test accuracy of the train-independent dataset was determined to be 97.27%. For segmentation, accuracy rates of 98.9% for train-dependent dataset and 92.82% for train-independent dataset for the proposed CNN were obtained in both nucleus and cytoplasm detection. In the presented study, the proposed method showed that it could detect white blood cells from a train-independent dataset with high accuracy. Additionally, it is promising as a diagnostic tool that can be used in the clinical field, with successful results in classification and segmentation.Item Biochemical And Molecular Analyses Of Insecticide Resistance In Greenhouse Populations Of Bemisia Tabaci (Hemiptera: Aleyrodidae) In Türkiye(Başkent Üniversitesi Fen Edebiyat Fakültesi, 2024-04-04) Erdogan, Cem; Toprak, Umut; Gurkan, M. OktayThe sweet potato/cotton whitefly Bemisia tabaci (Gennadius) (Hemiptera: Aleyrodidae) is one of the most destructive vegetable pests in greenhouses in Turkiye. While the preferred method of control primarily relies on insecticides such as neonicotinoids, organophosphates and pyrethroids, their intensive use has caused whiteflies to rapidly become resistant. Samples were collected from 13 Turkish B. tabaci greenhouse populations. Bioassays from the Marmara Region identified as high as a 53-fold increase in resistance to chlorpyrifos-ethyl, a 303-fold increase to imidacloprid and a 282-fold increase to acetamiprid. Bioassays in the Central Anatolia Region reported a 76-fold increase in resistance to deltamethrin and-15-fold increase to thiamethoxam. Most of the populations showed cross-resistance for neonicotinoids. All collected B. tabaci populations were determined to be MEAM 1 (also referred to as biotype B) for diagnostic band E0.14. The E0.14 esterase variant that helps to diagnose biotype B insects was found in all individuals from field populations. Almost all populations showed higher non-specific esterase, glutathione-S-transferase (GST) and monooxygenase activity when compared to susceptible SUD-S population. AChE insensitivity assays for individual B. tabaci suggest a target-site modification as a mechanism of resistance to chlorpyrifos-ethyl. This is the first report of AChE variants identified based on their sensitivities to chlorpyrifos ethyl-oxon and pirimicarb in Turkish B. tabaci populations. Fixed ace mutations in the target-site of organophosphates and pyrethroids were identified in six populations. Resistance to organophosphates and neonicotinoids were at least partially related to both ace mutations and insensitive AChE and monooxygenase activities, respectively. The results will help develop effective resistance management programs of B. tabaci in Turkiye.Item Evaluation of the Quality of Life and the Demographic and Clinical Characteristics of Patients With Pemphigus With Oral Mucosal involvement: A Multicenter Observational Study(Başkent Üniversitesi Sağlık Bilimleri Fakültesi, 2024-05-31) Polat, Asude Kara; Mulayim, Mehmet Kamil; Gur, Tugba Falay; Acar, Ayda; Bozca, Burcin Cansu; Ceylan, Can; Kilinc, Fadime; Guener, Rukiye Yasak; Albayrak, Huelya; Durdu, Murat; Aksu, Ayse Esra Koku; Nalbant, Fatma; Savk, Ekin; Bayramgurler, Dilek; Daye, Munise; Singer, Ralfi; Alatas, Emine Tugba; Erdemir, Vefa Asli; Gurel, Mehmet Salih; Uzun, Soner; Yayli, SavasIntroduction: Pemphigus vulgaris (PV) is an autoimmune disease primarily affecting the oral mucosa. Objectives: This study aimed to determine the demographic, clinical and treatment characteristics of PV patients with oral mucosal involvement and to assess the impact on their quality of life. Methods: We conducted a prospective observational study among 106 patients diagnosed with PV and presenting oral mucosal involvement. Demographic data, clinical and treatment characteristics, and quality of life questionnaires were recorded. Results: The study included 106 patients, 55 (51.89%) were male and there was a predominance of the mucocutaneous subtype in 83 individuals (78.38%). Oral mucosa was the initial site of manifestation in 44 patients (41.51%). Bilateral buccal mucosa was the most frequently affected site. The predominant symptom reported was a burning sensation, noted in 91 patients (85.85%). Oral mucosal examination revealed erosions in 85.85% of the patients. Systemic steroids were the most commonly administered treatment, and rituximab was used in 18 patients (16.98%). A positive and significant correlation was found between pemphigus severity and Oral Health Impact Profile-14, Dermatology Life Quality Index and Dermatological Quality of Life Scale scores (P < 0.05). The presence of superficial ulcers, flaccid bullae, lesion diameter >= 1 cm, and >10 lesions were factors that markedly diminished quality of life. Complete response to treatment was noted in all patients administered rituximab. Conclusions: The most common area of involvement was bilateral buccal mucosa, and the severity of PV closely correlated with a decline in quality of life measures. These results highlight the need for careful clinical oversight of PV, taking into account its effects on patients quality of life.Item The Role of Post-Traumatic Stress Symptoms and Post Migration Life Difficulties for Future Aspirations of Iraqi and Syrian Asylum Seekers(Başkent Üniversitesi Sağlık Bilimleri Fakültesi, 2024-07-12) Yildiz, Aylin Demirli; Strohmeier, DagmarThe majority of asylum seekers experience some kind of traumatic events before or during their flight and their challenging experiences do not end after resettlement. Still, they need to envision and build their future life in the host country. Moreover, asylum seekers' future aspirations need to be differentiated from the satisfaction of essential needs. We (1) measured future aspirations (FA); (2) explored whether FA and post-migration life difficulties (PMLD) differ between asylum seekers with high and low levels of post-traumatic stress symptoms (PTSS); and (3) examined whether PTSS, PMLD, gender, age, and length of stay are associated with different types of FA. In total, 139 Iraqi and Syrian asylum seekers (55 female, 83 male) aged 18 to 67 years (M = 34.03, SD = 10.35) participated. A four-factor structure of FA was confirmed by confirmatory factor analysis (CFA). Participants with high levels of post-traumatic stress symptoms reported higher levels of PMLD and lower levels of FA related to their home country. FA related to the host country and FA related to occupation were predicted by lower levels of post-traumatic stress symptoms, while future aspirations related to the home country were predicted by higher levels of PMLD. Results indicate that asylum seekers who experienced more traumatic events before they migrated are more reluctant to return to these places in the future. Treating the psychological impairments of this highly vulnerable group and relaxing the manifold structural barriers are crucial to foster their construction of a future life.Item Examination of Speech Analysis to Predict Suicidal Behavior in Depression(Başkent Üniversitesi Mühendislik Fakültesi, 2024-10-12) Yunden, S.; Ak, M.; Sert, M.; Gica, S.; Cinar, O.; Acar, Y. A.Item The Influence of Gender Roles on Eating Attitudes: A Study Among Female College Students Abstract(Başkent Üniversitesi Fen Edebiyat Fakültesi, 2024-10-12) Ozel, B.; Alici, Y. Hosgoren; Kocak, O. M.; Ceran, S.Item The Influence of Gender Roles on Eating Attitudes: A Study Among Female College Students(Başkent Üniversitesi Fen Edebiyat Fakültesi, 2024-10-12) Ozel, B.; Alici, Y. Hosgoren; Kocak, O. M.Item Comment on 'Accelerated Hypofractionated Chemoradiation For Locally Advanced Head And Neck Cancer During Covid-19 Pandemic: A Tertiary Care Experience'(Başkent Üniversitesi Diş Hekimliği Fakültesi, 2024-10-30) Somay, Efsun; Topkan, Erkan; Selek, Ugur; Pehlivan, BerrinItem A Pilot Study on Comparison of Teaching Workloads of Academicians Based on Working Periods During and Before the COVID-19 Pandemic(Başkent Üniversitesi Mühendislik Fakültesi, 2025-01-25) Yorulmaz, Muhammed; Can, Gulin Feryal; Toktas, PelinThe COVID-19 pandemic has had a profound impact on society, greatly changing the structure of social and working lives. Educational institutions, especially in higher education, were forced to suspend face-to-face education and switch to distance education. This change inevitably affected the working styles and workloads of academics. This study aims to explore the effects of the COVID-19 pandemic on academic teaching workloads by examining transaction data for a one-year period before and during the pandemic. The data were obtained from the system logs of a learning management system platform, which was used extensively during the pre-pandemic and pandemic periods, and were analyzed in terms of transaction density, day, and time of transactions. The findings from the pre-pandemic period showed that the academic workload was higher on weekdays than on weekends. However, with the transition to distance education during the pandemic, the difference between weekday and weekend workloads diminished significantly. Additionally, the working hours shifted during the pandemic by approximately one hour to later hours in the day.Item Is There A Relationship Between The Severity Of Disease İn Major Depressive Disorder Patients And Dry Eye Disease?(Başkent Üniversitesi Fen Edebiyat Fakültesi, 2024-04-05) Gokce, Gizem Dogan; Metin, MervePurposeTo investigate dry eye disease (DED) in newly diagnosed patients with depressive disorder (MDD). MethodThis observational study included 48 MDD patients in Group 1 and 20 healthy controls in Group 2. Psychiatric and ophthalmic examinations, Beck Depression Inventory (BDI), Ocular Surface Disease Index (OSDI), Schirmer's test, tear breakup time (TBUT), Meibomian gland dysfunction (MGD), and ocular staining were conducted. The results were statistically compared. ResultsThe participants, comprising 32 men and 36 women, had a mean age of 31.08 +/- 11.7 years (18-64 years). Group 1 had a mean BDI score of 30.87 +/- 8.56, while Group 2 had a score of 1.3 +/- 1.3 (p < 0.001). In Group 1, 28 patients were diagnosed with DED, whereas in Group 2, six subjects were diagnosed with DED. The mean Schirmer's results in Group 1 and Group 2 were (mm/5 min) 10.87 +/- 2.44 and 12.70 +/- 2.3, respectively, and were significantly lower in Group 1 (p < 0.001). The mean OSDI scores in Group 1 (34.95 +/- 15.8) were significantly higher compared to Group 2 (3.2 +/- 3.1) (p < 0.001). There was no significant difference in mean TBUT between Group 1 (9.41 +/- 2.6 s) and Group 2 (9.8 +/- 0.61 s) (p > 0.05). Significant correlations were found between BDI scores and Schirmer's results as well as OSDI scores (p < 0.05, p = 0.02, respectively). No statistically significant correlations were found between BDI scores and TBUT or MGD (p > 0.05). ConclusionDED was found to be more prevalent in the MDD group. The severity of MDD and DED, as indicated by BDI, OSDI, and Schirmer's results, was found to be correlated. It was observed that patients with higher depression scores had more severe dry eye. As a result, we recommend performing ophthalmic examinations in newly diagnosed MDD patients.