Tıp Fakültesi / Faculty of Medicine
Permanent URI for this collectionhttps://hdl.handle.net/11727/1403
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Item Embolization of Pulmonary Sequestration with Onyx: An Unusual Application(2014) Gursu, Alper Hazim; Boyvat, Fatih; Varan, Birgul; Erdogan, Ilkay; https://orcid.org/0000-0002-0707-2678; https://orcid.org/0000-0002-6719-8563; https://orcid.org/0000-0001-6887-3033; 24643150; AHI-4502-2022; F-4230-2011; ABB-1767-2021; ABB-2220-2021We report a baby with intralobar pulmonary sequestration who was successfully treated with a new embolization agent, Onyx. A 1.5-month-old female infant was admitted to our hospital with sweating and fatigue. Telecardiography showed cardiomegaly, dextrocardia, and increased pulmonary vascular markings. In thoracic computerized tomography, pulmonary sequestration, right pulmonary hypoplasia, and large collateral arteries were seen. The collateral arteries were originating from the celiac trunk and aorta. Echocardiography revealed enlargement of the left atrium and ventricle and left ventricle systolic dysfunction. Angiography revealed a large feeding artery and three branches originating from the aorta and another feeding artery originating from the celiac trunk. We performed embolization of the feeding arteries and their branches, with coils and Onyx. The procedure was performed without complications, and all feeding arteries were completely occluded. The infant started to gain weight. One year later, the infant's body weight had increased and she had no respiratory problems or signs of congestive heart failure. In this case report, we suggest that embolization with Onyx is a reliable alternative method to surgery for infants with pulmonary sequestration. With future studies, pulmonary sequestration embolization with Onyx may become an acceptable and easy treatment option in pediatric patients.Item Short-Term Results of Neurelec Digisonic SP Cochlear Implantation in Prelingually Deafened Children(2014) Senkal, Ozgul Akin; Hizal, Evren; Yavuz, Haluk; Yilmaz, Ismail; Ozluoglu, Levent Naci; https://orcid.org/0000-0002-3554-8274; https://orcid.org/0000-0002-9699-6783; https://orcid.org/0000-0003-3320-204X; https://orcid.org/0000-0002-1694-7608; https://orcid.org/0000-0002-2150-0237; 23749057; F-9493-2013; A-5853-2018; F-6315-2015; AAJ-2992-2021; AAI-8020-2021This paper examines the reports on the selection criteria and the post-operative performance of 25 children implanted with the Neurelec Digisonic SP. This study reported benefits from Neurelec Digisonic SP cochlear implant in auditory and speech perception outcomes. There has been a lack of studies into the additional factors such as level of the mothers' education and bilingualism, which is a factor that may have a significant effect on the success of cochlear implantation. This paper examines the reports on the reasons for the differences in performance and the post-operative performance of 25 children implanted with the Neurelec Digisonic SP. Meaningful Auditory Integration Scale and Meaningful Use of Speech Scale questionnaires were used just before 3, 6, 12, and 18 months following implantation. Electrode array was inserted without difficulty in all cases, with no complications to date. This is a retrospective and cross-sectional study and all the data were collected between March 2010 and December 2012. Auditory performance improved over time for up to 12 months after implantation. Our experience indicates that the Neurelec Digisonic SP cochlear implant system in children under the age of two is relatively safe and reliable. The Neurelec Digisonic SP device surgery can be performed without complications. Auditory performance results support the effectiveness of early implantation. These important findings further support the importance of professionals working very closely with parents or especially mothers and enhancing their involvement in achieving therapy goals to develop auditory skills and speech in young children following cochlear implantation.Item Is the Grade of Vesicoureteral Reflux Related with Detrusor Overactivity?(2014) Kilinc, Ferhat; https://orcid.org/0000-0001-9506-0046; AAL-6156-2021Aim: The videourodynamic study outcomes in patients with vesicoureteral reflux were retrospectively reviewed. The aim of this study is to evaluate the relationship between the idiopathic detrusor overactivity and the grade of vesicoureteral reflux. Material and Method: We reviewed retrospectively the videourodynamic traces of 71 vesicoureteral reflux patients without neuropathic conditions. Patients were divided into two groups: Patients without concomitant detrusor overactivity (Group 1), and patients with concomitant detrusor overactivity (Group 2). The reflux grades were divided into two grades; low-grade reflux (grades 1 and 2), high-grade reflux (grades 3, 4 and 5). Data were analyzed using the chi-square test. Results: Patients ages ranged between 5 and 16 years (mean 8.37 +/- 2.97 years). Of the 71 patients, 39 (54.9%) had a normal detrusor activity (Group 1), 32 (45.1%) had a detrusor overactivity (Group 2). Twenty-five (64.1%) patients in-group 1 had a low-grade reflux, 14 (35.9%) patients had a high-grade reflux. In-group 2, 17 (53.1%) patients had a low-grade reflux, 15 (46.9%) patients had a high-grade reflux. There was no significant difference between the two groups (p=0.488). Discussion: The idiopathic detrusor overactivity can be observed during urodynamic investigation of patients with vesicoureteral reflux, but it has no effect on the grade of reflux.Item A Case of Seckel Syndrome with Tricuspid Atresia(2014) Arslan, D.; Cimen, D.; Guvenc, O.; Sert, A.; Oktay, A.; Oran, B.; 25059015A case of Seckel syndrome with tricuspid atresia: Seckel syndrome is an autosomal recessive disease presenting with marked growth retardation, microcephalic dwarfism, some facial and skeletal abnormalities. Tricuspid atresia is a rare and life threatening cyanotic congenital heart diseases, with an incidence of 1% to 3%. It is feature of the anatomically normally related great arteries with a large ventricular septum defect and stenosis of right ventricular outflow tract. Tricuspid atresia has never been reported in patients with Seckel syndrome. Here we report a 15-day-old girl baby diagnosed as having Seckel syndrome with tricuspid atresia.Item Hoarseness in School-Aged Children and Effectiveness of Voice Therapy in International Classification of Functioning Framework(2015) Senkal, Ozgul Akin; Ozer, Cem; 0000-0002-3554-8274; 0000-0002-6641-5300; 25998409; F-9493-2013; E-8576-2018; ABH-1785-2020Objectives. The hoarseness in school-aged children disrupts the educational process because it affects the social progress, communication skills, and self-esteem of children. Besides otorhinolaryngological examination, the first treatment option is voice therapy when hoarseness occurs. The aim of the study was to determine the factors increasing the hoarseness in school-aged children by parental interview and to know preferable voice therapy on school-aged children within the frame of International Classification of Functioning (ICF). Study Design. Retrospective analysis of data gathered from patient files. Method. A total of 75 children (56 boys and 19 girls) were examined retrospectively. The age range of school-aged children is 7-14 years and average is 10.86 +/- 2.51. A detailed history was taken from parents of children involved in this study. Information about vocal habits of children was gathered within the frame of ICF and then the voice therapies of children were started by scheduling appointments by an experienced speech-language pathologist. Results. The differences between before and after voice therapy according to applied voice therapy methods, statistically significant differences were determined between maximum phonation time values and s/z rate. The relationship between voice therapy sessions and s/z rate with middle degree significance was found with physiological voice therapy sessions. According to ICF labels, most of voice complaints are matching with "body functions'' and "activity and limitations.'' Conclusions. The appropriate voice therapy methods for hoarseness in school-aged children must be chosen and applied by speech-language therapists. The detailed history, which is received from family during the examination, within the frame of ICF affects the processes of choosing the voice therapy method and application of them positively. Child's family is very important for a successful management.Item The Effects of Electromagnetic Field on the Endocrine System in Children and Adolescents(2015) Sangun, Ozlem; Dundar, Bumin; Comlekci, Selcuk; Buyukgebiz, Attila; 0000-0002-9079-4574; 26841641; C-3882-2008Children are exposed to various kind of non-ionizan radiation in their daily life involuntarily. The potential sensitivity of developing organism to the effects of radiofrequency (RF) signals, the higher estimated specific absorption rate (SAR) values of children and greater lifetime cumulative risk raised the scientific interest for children's vulnerability to electromagnetic fields (EMFs). In modern societies, children are being exposed to EMFs in very early ages. There are many researches in scientific literature investigating the alterations of biological parameters in living organisms after EMFs. Although the international guidelines did not report definite, convincing data about the causality, there are unignorable amount of studies indicating the increased risk of cancer, hematologic effects and cognitive impairment. Although they are less in amount; growing number of studies reveal the impacts on metabolism and endocrine function. Reproductive system and growth look like the most challenging fields. However there are also some concerns on detrimental effects of EMFs on thyroid functions, adrenal hormones, glucose homeostasis and melatonin levels. It is not easy to conduct a study investigating the effects of EMFs on a fetus or child due to ethical issues. Hence, the studies are usually performed on virtual models or animals. Although the results are conflicting and cannot be totally matched with humans; there is growing evidence to distress us about the threats of EMF On children.Item Tic Disorder Probably Associated with Steroid Responsive Encephalopathy with Autoimmune Thyroiditis (SREAT)(2014) Saygi, Semra; Ozkale, Yasemin; Erol, Ilknur; https://orcid.org/0000-0002-8522-5078; https://orcid.org/0000-0003-3009-336X; 24633901; AAB-1203-2021; AAL-6136-2021Steroid responsive encephalopathy with autoimmune thyroiditis (SREAT), a rare disorder in individuals of all age groups, including children, is characterized by high titers of anti-thyroid peroxidase antibodies. The present report concerns a previously healthy 12-y-old boy who presented with motor tics. The patient underwent an extensive work-up to identify the underlying etiologies and risk factors predisposing him to tic disorder. Based on the clinical and laboratory results, a diagnosis of SREAT was made. Although some studies have reported associated behavioral and cognitive changes, myoclonus, seizures, pyramidal tract dysfunction, psychosis, and coma. The authors describe a case of tic disorder, probably due to SREAT, as well as its course of treatment.Item A Rare Cardiovascular Finding in Two Cases with Williams Syndrome: Recurrent Coarctation of Aorta(2015) Ari, Mehmet Emre; Erdogan, Ilkay; Varan, Birgul; Ozkan, Murat; 0000-0002-6719-8563; 0000-0001-6887-3033; 0000-0001-7932-1074; ABB-1767-2021; ABB-2220-2021; W-1590-2017Williams syndrome is a genetic disorder caused by multiple gene deletions on chromosome 7. The majority of the cases is sporadic and has typical facial appearance, cardiac anomalies and mental retardation. Cardiovascular anomalies are present in about 80% of the cases, most frequently supravalvular aortic stenosis and pulmonary arterial stenosis. In this article, we report two pediatric cases with a rapidly progressive form of aortic coarctation, each of whom required two surgeries and two percutaneous balloon dilatations within the first five months of life.Item Association Between Vitamin D Deficiency and Anemia in Pediatric Kidney Transplant Recipients(2022) Avci, Begum; Baskin, Esra; Gulleroglu, Kaan; Yilmaz, Aysun Caltik; Karakaya, Emre; Moray, Gokhan; Haberal, Mehmet; 0000-0003-1434-3824; 0000-0002-3462-7632; 0000-0002-4879-7974; 0000-0003-0774-4419; 35570598; AAJ-8833-2021; AAJ-8097-2021; AAD-5466-2021; AAD-1877-2021Objectives: The association between vitamin D deficiency and anemia is known. Vitamin D deficiency and anemia are common in kidney transplant recipients. We examined the relationship between vitamin D levels and anemia in pediatric kidney transplant recipients. Materials and Methods: We reviewed retrospectively the data of 75 pediatric kidney transplant recipients (0-18 years of age). Patients were evaluated in 3 groups according to serum 25-hydroxyvitamin D levels (<20, 20-30, and >30 ng/mL) in the first year posttransplant: group 1 was the vitamin D deficiency group, group 2 was the vitamin D insufficiency group, and group 3 was normal vitamin D level group, respectively. Groups were compared in terms of anemia parameters, calcium, phosphorus, alkaline phosphatase, and parathyroid hormone levels, as well as infection, rejection, and graft loss status. All patients included in the study were grouped as those with anemia and without anemia, and the 2 groups were compared in terms of vitamin D levels, serum parathyroid hormone values, estimated glomerular filtration rate, and infection, rejection, and graft loss status. Results: There were 41 patients (54.7%) in group 1, 24 patients (32%) in group 2, and 10 patients (13%) in group 3. There were 65 patients (86.7%) with vitamin D deficiency/insufficiency. When groups were compared, the hematocrit level was found to be lower in groups 1 and 2 (P < .05) and ferritin level was found to be lower in group 1 (P < .05). Anemia was present in 20 patients (26.6%): 61% of patients with anemia had vitamin D deficiency and 33% had vitamin D insufficiency (P > .05). In total, 94% of patients with anemia had vitamin D deficiency/insufficiency. Conclusions: Vitamin D deficiency/insufficiency is common in pediatric kidney transplant recipients. Vitamin D levels should be measured, especially in all kidney transplant recipients with persistent anemia. Thus, risk factors associated anemia can be reduced by treating the deficiency/insufficiency.Item Serum Vitamin D Levels in Children with Recurrent Respiratory Infections and Chronic Cough(2016) Ozdemir, Beril; Koksal, Burcu Tahire; Karakas, Nazmi Mutlu; Tekindal, Mustafa Agah; Ozbek, Ozlem Yilmaz; 0000-0003-2974-9579; 0000-0003-4286-7086; 0000-0001-9580-7656; 0000-0002-4060-7048; 26821547; AAJ-2034-2021; HKW-0623-2023; AAX-3831-2020; AAF-2109-2021; U-9270-2018Objectives To evaluate serum vitamin D levels in cases of recurrent respiratory infections and chronic cough and to investigate the effect of vitamin D therapy on recurrence of the diseases. Methods This prospective observational study was performed by comparing serum vitamin D levels in children with recurrent respiratory infections, chronic cough and healthy children. One-hundred-one children with chronic cough, ninety-eight children with recurrent respiratory infections and one-hundred-twenty-four healthy children were enrolled in the study. A structured questionnaire was completed to collect data on demography, diet, duration of breastfeeding, vitamin D supplementation and family history for allergic diseases. In patients with low serum vitamin D levels (<20 ng/ml), vitamin D therapy was administered in addition to conventional treatment for the diseases. Patients were followed up for 6 mo and their complaints were evaluated. Results Mean serum 25( OH) vitamin D level in the recurrent respiratory infections group was 11.97 +/- 4.04 ng/ml, chronic cough group was 13.76 +/- 4.81 ng/ml and control group was 31.91 +/- 18.79 ng/ml. Comparison of serum 25( OH) vitamin D levels between the study groups revealed a statistically significant difference ( p < 0.05). 25( OH) D deficiency in children was associated with increased frequency of recurrent respiratory infections and chronic cough. Conclusions To conclude, administration of supplementary vitamin D may be useful in the treatment and preventation of recurrent respiratory infections and chronic cough.