Tıp Fakültesi / Faculty of Medicine

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    Neutrophil to Lymphocyte Ratio As A Predictor of Severe Coronary Artery Disease and Left Ventricular Systolic Dysfunction of Any Degree in Geriatric Patients Presenting to Emergency Department with Acute Coronary Syndrome
    (2017) Ciftci, Orcun; Kayipmaz, Afsin Emre; Aydos, Tolga Resat; Muderrisoglu, Ibrahim Haldun; 0000-0002-1832-9336; 0000-0001-8926-9142; AAJ-7279-2020; AAC-2597-2020; W-5233-2018
    Introduction: We examined the role of the neutrophil-to-lymphocyte ratio (NLR) for predicting severe coronary artery disease and left ventricular systolic dysfunction of any degree in geriatric patients presenting to emergency department with non-ST-elevation acute coronary syndrome. Materials and Method: We retrospectively reviewed data for patients aged >= 65 years with non-ST-elevation acute coronary syndrome who underwent coronary angiography between April 2011 and January 2016. Patients were divided into Group 1 (101 patients; severe [>50%] lesions in one or more epicardial artery or branch) and Group 2 (65 patients; no severe lesions). The key clinical parameters, including NLR were compared among the groups and the power of NLR as a predictor of severe coronary artery disease and left ventricular systolic dysfunction of any degree was determined. Results: Group 1 included more patients who were male, older, or smoked; these had higher troponin I, mass CK-MB, NLR, but a lower left-ventricular ejection fraction. NLR was an independent predictor of severe coronary disease and left ventricular systolic dysfunction of any degree with good sensitivity and moderate specificity. Conclusion: Neutrophil-to-lymphocyte ratio is a simple, rapid, and cheap parameter that can predict severe coronary artery disease and left ventricular systolic dysfunction of any degree in geriatric patients with non-ST-elevation acute coronary syndrome.
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    A Study Which Investigates the Relationship of Age, Trunk Strength, and Balance Parameters with Fall Risk
    (2016) Sencan, Savas; Ayas, Sehri; Saracgil Cosar, Sacide Nur; 0000-0002-5078-6529; AAJ-7520-2021
    Introduction: Age-related neural and sensory deteriorations and decline of the musculoskeletal systems affect balance and increase the risk of fall. Our objective in this study is to determine how balance and the risk of fall are affected by increasing age, and search the role of trunk muscle strength on balance. Materials and Method: A total of 90 female voluntary participants were divided into the age groups of 20-39, 40-59 and >= 60 years (n = 30 for each group). Static balance abilities and the fall risks of the subjects were determined using a computer-aided static posturography device and their trunk muscle strength at 60 degrees/s and 120 degrees/s were assessed using the isokinetic dynamometer equipment. Results: When the 20-39 age groups are compared with 40-59 and 3 60 age groups regarding the balance measurements, higher index values at low and medium frequency oscillations were detected. Assessment of the correlation between age and Fourier indexes showed that more balance scores were found to deteriorate with increasing age. The deterioration in the balance parameters was observed to be correlated with the trunk flexor and extensor muscle strength, reducing with increasing age. Conclusion: It was determined that static balance parameters tend to deteriorate and the risk of falls increases with increasing age. The decreasing trunk muscle strength was found to be related to the decline in balance ability and an increased risk of falling.
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    Europathic Pain in Elderly: A Multicenter Study
    (2016) Kutsal, Yesim Gokce; Eyigor, Sibel; Dogan, Asuman; Zardoust, Sasan; Durmus, Bekir; Evcik, Deniz; Gunaydin, Rezzan; Sahin, Nilay; Aydeniz, Ali; Oztop, Pinar; Gokkaya, Kutay O.; Hizmetli, Sami; Borman, Pinar; Paker, Nurdan; Demir, Gulseren; Kayalar, Gulseren; Aydin, Ezgi; Ozyemisci, Ozden
    Introduction: Aging brings with it an increase in the prevalence of pain. For effective pain treatment, it is important to determine pain prevalence, its nature, and the factors affecting it. However, epidemiologic information on neuropathic pain in the elderly is inadequate. In our cross-sectional multicenter study, we aimed to determining the prevalence of neuropathic pain in elderly patients and the relationship of neuropathic pain with socio-demographic and clinical factors. Materials and Method: Thirteen centers in different regions of Turkey. The study included 1163 individuals over age 65. Physicians conducted face-to-face interviews to obtain clinical and socio-demographic data and The Douleur Neuropathic 4 (DN4) and The Self-completed Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) pain scales were used to assess neuropathic pain. Patients who scored >= 4 or >= 12 on the DN4 and S-LANSS scales, respectively, were determined to be experiencing neuropathic pain. Results: Neuropathic pain was found in 52.5% of the patients (n=610) in this study. Approximately 67.5% of the patients with neuropathic pain were in the 65-74 age group, and 72.1% (n=440) were females. Of the patients who were experiencing neuropathic pain, 48.4% were graduates of primary school, 91.6% engaged in very little or no physical activity, and 56.7% were taking four or more medications. Conclusions: Neuropathic pain prevalence was 52.5% in the elderly over age 65 who had presented with pain complaints. Neuropathic pain was more frequently seen in women, patients with comorbidities, those with poor levels of ambulation, those using walking aids, and those using multiple drugs. Interrogating the elderly for neuropathic pain seems important for effective treatment.