Tıp Fakültesi / Faculty of Medicine

Permanent URI for this collectionhttps://hdl.handle.net/11727/1403

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2015 - 20192

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search.filters.applied.f.language: search.filters.language.turSubject: search.filters.subject.Multiple sclerosis

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    Childhood traumas in patients with multiple sclerosis and its relationship with suicide probability
    (2019) Ulusoy, Selen Isik; Horasanli, Bahriye
    Objective: It is known that suicide probability is more than the normal population in patients with multiple sclerosis (MS). It has been reported that childhood trauma increases suicide probability in many psychiatric disorders. The aim of this study is to investigate the relationship between childhood traumas and the probability of suicide in patients with MS..Method: The study included 61 patients with MS. The functional status of the patients with MS was evaluated with the Expanded Disability Status Scale (EDSS). Hospital Anxiety Depression Scale (HAD), Childhood Trauma Inventory (CTQ-28) and Suicide Probability Scale (SPS) were applied to all patients. Results: The patients were divided into two groups as 26 patients with childhood trauma (CTQ >= 35) and 35 patients without childhood trauma (CTQ<35). The most common childhood trauma was emotional neglect (n=28; 45,90%) and the patients' mean EDSS score was 2.43 +/- 1.68. The mean of HAD anxiety subscale (HAD-A) scores (p=0,005), HAD depression subscale (HAD-D) scores (p=0,034), SPS despair subscale scores (p=0,031) and SPS total scores (p=0,020) were higher in patients with childhood trauma. All CTQ subscales, except physical neglect, were found positively correlated with the SPS total score. Discussion: Suicide probability was significantly higher in patients with MS with childhood trauma. Patients should be evaluated in terms of childhood traumas in order to take necessary measures for suicide probability and to perform correct interventions in patients with MS.
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    A Case of Multiple Sclerosis Presented with 5th, 6th and 7th Cranial Nerve Paralysis
    (2015) Sarıgul, Almila; Bayar, Sezin Akca; Singar, Evin; Pinarci, Eylem Yaman; Oto, Sibel
    A 36-year-old female patient was admitted to our clinic with complaints of numbness in hands, double vision, and inability to close her left eye. Her physical examination revealed horizontal diplopia, underactivity of the left lateral rectus muscle, left peripheral facial paralysis, and trigeminal sensorial neuropathy. The magnetic resonance imaging revealed hyperintense lesions, which were compatible with multiple sclerosis (MS). Therefore, systemic steroid treatment (1000 mg/day intravenous methylprednisolone for 5 days, 1 mg/kg/day oral prednisolone, reduced slowly) was administered to the patient. Within five weeks, her symptoms were regressed, and no recurrence was observed during the follow-up period of 4 years. As this case proves, MS can present with cranial nerve palsies in addition to many other different neurological symptoms. Although 5th nerve palsy is the most common cranial nerve palsy detected in MS patients, 7th and 6th nerve involvement are rarely reported in the literature. MS should always be considered in the differential diagnosis of cranial nerve palsies especially in young patients.