Tıp Fakültesi / Faculty of Medicine
Permanent URI for this collectionhttps://hdl.handle.net/11727/1403
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Item Clinical Characteristics and Outcomes of Nosocomial COVID-19 in Turkey: A Retrospective Multicenter Study(2023) Yildirim, Suleyman; Yilmaz, Celalettin; Polat, Gulru; Baris, Serap; Basyigit, Ilknur; Kaya, Ilknur; Anar, Ceyda; Bozkurt, Mihriban; Baykal, Husnu; Dirol, Hulya; Ozbey, Gamzenur; Ozsari, Emine; Cireli, Emel; Cirak, Ali; Tatar, Dursun; Gayaf, Mine; Karaoglanoglu, Selen; Aydin, Yener; Eroglu, Atilla; Olcar, Yildiz; Yildirim, Berna; Gursoy, Bengul; Yilmaz, Deniz; Niksarlioglu, Elif; Eren, Ramazan; Erdem, Aysegul; Tor, Muge Meltem; Fakili, Fusun; Colak, Mustafa; Ercelik, Merve; Tabaru, Ali; Ediboglu, OzlemObjective: To identify the clinical characteristics and outcomes of hospital-acquired SARS-CoV-2 infection during the vaccination period nationwide in Turkey. Methods: COVID-19 patients followed in the pandemic services across Turkey between January 1, 2021, and March 31, 2022 were investigated retrospectively. Nosocomial COVID-19 was defined as a patient neither diagnosed with COVID-19 nor suspected COVID-19 at the hospital admission and was confirmed COVID-19 >= 5 days after hospital admission. The primary outcome of this study was in-hospital mortality; demographic features and vaccination status was compared between survivors and non survivors. Results: During the study period, 15 573 COVID-19 patients were followed in 18 centers and 543 (3.5%) patients were nosocomial COVID-19. Most patients with nosocomial COVID-19 (80.4%) were transferred from medical wards. 162 (29.8%) of the patients with nosocomial COVID-19 admitted to the intensive care unit due to disease severity and 138 (25.4%) of the patients died during hospital stay. Advanced age (>= 65 years) and number of comorbid diseases (>= 2) was found to be associated with mortality in nosocomial COVID-19 (OR 1.74, 95% CI 1.11-2.74 and OR 1.60, 95% CI 1.02-2.56, respectively). Vaccination was associated with survival in nosocomial COVID-19 (OR 0.25, 95% CI0.16-0.38). Conclusions: Patients with nosocomial COVID-19 had increased admission to intensive care units and higher mortality rate. Vaccination can decrease the in-hospital mortality rate.Item Influence of Influenza Vaccination on Recurrent Hospitalization in Patients with Heart Failure(2017) Kaya, H.; Beton, O.; Acar, G.; Temizhan, A.; Cavusoglu, Y.; Guray, U.; Zoghi, M.; Ural, D.; Ekmekci, A.; Gungor, H.; Sari, I.; Oguz, D.; Yucel, H.; Zorlu, A.; Yilmaz, M. B.; 27460050The current study aimed to evaluate the influence of regular annual influenza vaccinations on cardiovascular (CV) death and heart failure-related hospitalizations (HFrH) in stable outpatients with heart failure with reduced ejection fraction. The Turkish research team-HF (TREAT-HF) is a network undertaking multicenter, observational cohort studies in HF. This study is a subgroup analysis of TREAT-HF outpatient cohorts who completed a questionnaire on influenza vaccination status and for whom follow-up data were available. A total of 656 patients with available follow-up data for CV death and HFrH including recurrent hospitalization were included in the study. Patients were classified into two groups: those who received regular influenza vaccination (40 %) and those who did not receive vaccination. During a mean follow-up of 15 +/- 6 months, 113 (18 %) patients had CV death and 471 (72 %) patients had at least one HFrH. The CV death rate was similar in both groups of patients (16 vs. 19 %, p = 0.37), whereas, HFrH and recurrent HFrH were significantly less frequently encountered in patients who received regular influenza vaccination than in those who did not receive vaccination (43 vs. 92 % and 16 vs. 66 %, p < 0.001, respectively). In a multivariate Cox proportional hazards model - in addition to a few clinical factors - vaccination status (HR = 0.30, 95 % CI = 0.17-0.51, p < 0.001) and graduation from university (HR = 0.35, 95 % CI = 0.17-0.72, p = 0.004) remained independently associated with the risk of recurrent HFrH. Regular influenza vaccination does not influence CV deaths; however, it decreases HFrH including recurrent episodes of HFrH in outpatients with heart failure with reduced ejection fraction.Item Significance of electronic health records: A comparative study of vaccination rates in patients with sickle cell disease(2017) Korur, Asli; Asma, Suheyl; Gereklioglu, Cigdem; Solmaz, Soner; Boga, Can; Ozsahin, Akatli Kursat; Kut, Altug; 0000-0002-5086-5593; 0000-0001-8844-3946; 0000-0002-8902-1283; 0000-0001-5335-7976; 0000-0003-0776-8349; 0000-0002-9680-1958; 28811769; AAD-5616-2021; AAL-6544-2020; AAN-3522-2021; AAD-5542-2021; AAD-6222-2021; AAI-7831-2021; A-2550-2015Objective: In this study, we investigated the influence of electronic health records (EHR) and electronic vaccination schedule applications on the vaccination status of patients who were admitted to our Center for the treatment of sickle cell disease (SCD). Methods: The vaccination status against influenza and pneumococcus infection was determined in 93 patients who were admitted to the hematology outpatient clinic, Baskent University Adana Hospital from April 2004 to March 2009. The vaccination status was then re-evaluated following establishment of EHR and electronic vaccination schedules in 2012. Results: Of the 93 patients with SCD 21.5% (n=20) were vaccinated against pneumococcus and 21.5% (n=20) were regularly vaccinated against influenza. When the vaccination rates of 59 of 93 patients who presented for their regular control examinations were analyzed following establishment of EHR and vaccination schedules in 2012, these rates were 49.2% (n=29) and 50.8% (n=30) for influenza and pneumococcus, respectively, after EHR; there were 23.7% (n=14) and 20.3% (n=12), respectively, before EHR. A statistically significant difference was found between the vaccination rates before and after EHR (p < 0.05). Conclusion: Although viral and bacterial infections are life-threatening health problems in patients with SCD, the vaccination rates were low in high-risk patients. However, these rates increased after application of electronic vaccination schedules.Item Vaccination of adults with heart failure and chronic heart conditions: Expert opinion(2018) Celik, Ahmet; Altay, Hakan; Azap, Alpay; Cavusoglu, Yuksel; Nalbantgil, Sanem; Senol, Esin; Temizhan, Ahmet; Yilmaz, Mehmet Birhan; 30516533