Tıp Fakültesi / Faculty of Medicine

Permanent URI for this collectionhttps://hdl.handle.net/11727/1403

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search.filters.applied.f.language: search.filters.language.engSubject: search.filters.subject.Intraocular pressure

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    The Effect of Spinal Versus General Anesthesia on İntraocular Pressure in Lumbar Disc Surgery in The Prone Position: A Randomized, Controlled Clinical Trial
    (2018) Pinar, Huseyin Ulas; Kasdogan, Zumrut Ela Arslan; Basaran, Betul; Coven, Ilker; Karaca, Omer; Dogan, Rafi; https://orcid.org/0000-0003-0473-6763; https://orcid.org/0000-0003-1933-2075; 29414618; Q-2420-2015; GQO-9198-2022
    Objective: To compare IOP changes between spinal anesthesia (SA) and general anesthesia (GA) in patients who underwent lumbar disc surgery in the prone position. Design: Prospective, randomized, controlled trial. Setting: Operating room. Patients: Forty ASA I-II patients scheduled for lumbar disc surgery in prone position. Intervention: Patients were randomly allocated to the SA or GA groups. Measurements: IOP was measured before anesthesia (IOP1), 10 min after spinal or general anesthesia in supine position (IOP2), 10 min after being placed in the prone position (IOP3), and at the end of the operation in the prone position (IOP4). Main results: There was no significant difference between baseline IOP1 (group GA = 19.4 +/- 3.2 mmHg; group SA = 18.6 +/- 2.4 mmHg) and IOP2 values (group GA = 19.7 +/- 4.1 mmHg; group SA = 18.4 +/- 1.9 mmHg) between and within the groups. IOP values after prone positioning and group GA measurements (IOP3 = 21.6 +/- 3.1 mmHg; IOP4 = 33.9 +/- 3.1 mmHg) were significantly higher when compared with the SA group (IOP3 = 19.3 +/- 2.7 mmHg, IOP4 = 26.9 +/- 2.4 mmHg) (p = 0.018 and p < 0.001, respectively). Furthermore, IOP3 was significantly increased when compared with IOP2 in the GA group but not in the SA group (p = 0.019 and p = 0.525, respectively). In both groups, IOP4 values were significantly higher than the other three measurements (p < 0.001). Conclusion: The results indicated that IOP increase is significantly less in patients who undergo lumbar disc surgery in the prone position under SA compared with GA.
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    Intraocular pressure in subjects with beta-thalassemia minor
    (2019) Keskek, Sakir Ozgur; Keskek, Nedime Sahinoglu; Ilgin, Gizem; Sukgen, Emine; 30810618
    Purpose: Beta-thalassemia minor, a common hereditary blood disorder in Mediterranean countries such as Turkey, is associated with insulin resistance. Insulin resistance, in turn, can be associated with excessively high intraocular pressure and, therefore, intraocular pressure-induced blindness. This study aimed to investigate the intraocular pressure in subjects with beta-thalassemia minor. Methods: We conducted a cross-sectional study comprising of 203 subjects divided into two groups: beta-thalassemia minor (103) and healthy (100). Hemoglobin electrophoresis was performed and complete blood count, blood pressures, serum fasting glucose and insulin levels were measured. All subjects underwent ophthalmological examinations including intraocular pressure measurements. Results: Intraocular pressure in the subjects with beta-thalassemia minor was significantly lower than that in healthy subjects (p=0.007). Additionally, intraocular pressure was inversely correlated with hemoglobin A(2) levels (p=0.001, r=-0.320). Serum insulin and systolic blood pressure were significantly higher in subjects with beta-thalassemia minor (p=0.03, p=0.009, respectively). Conclusion: Subjects with beta-thalassemia minor had lower intraocular pressure than healthy controls, suggesting beta-thalassemia minor may actually protect against high intraocular pressure.