Tıp Fakültesi / Faculty of Medicine

Permanent URI for this collectionhttps://hdl.handle.net/11727/1403

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    Complex Regional Pain Syndrome in an Adult Following Tetanus-Diphteria Toxoid Vaccine: Case Report and Review of the Literature
    (2014) Seyrek, Aslihan; Yemisci, Oya Umit; Sozay, Seyhan; https://orcid.org/0000-0002-0501-5127; https://orcid.org/0000-0002-8460-7699; AAJ-8820-2021; AAJ-2936-2021
    Background: Complex regional pain syndrome [CRPS] is a painful and disabling chronic neuropathic disorder, and unfortunately, due to its wide spectrum of clinical manifestations, the diagnosis may often be missed by primary-care physicians. To the authors' knowledge, there are no reported cases of CRPS following immunization with tetanus-diphteria toxoid booster vaccine in an adult. Findings: We present a 26-year-old woman with severe pain, swelling, and limited range of motion of the left forearm following a booster dose of the tetanus-diphteria toxoid vaccine. Conclusion: Disease awareness among practitioners, early recognition, and appropriate treatment is essential to minimize the risk of adverse outcome.
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    Anorectal Malformation in an Adult Associated with Chronic Renal Failure: A Case Report
    (2017) Ezer, Ali; Ezer, Semire S.; Parlakgumus, Alper; 0000-0002-3834-9924; 0000-0002-9597-3264; AAJ-8558-2021; AAJ-9529-2021
    Few adult cases suffering from anorectal malformation have been concerned in literature; therefore, little is known about the best approach for managing this matter in adults. Our case is a 24 years old female patient admitted to our center with recurrent urinary tract infections and fecal incontinence. She was in hemodialysis program for 1 year due to chronic renal failure. During clinical examination, rectovestibular fistula was detected. Initially, sigmoid loop colostomy was formed. After 10 days, posterior sagittal anorectoplasty (PSARP) was applied and after 3 months, closure of the colostomy was practiced. Total continence reconstruction was achieved. 8 months after all these processes, kidney transplant from our patient's mother was performed and the patient was back to her normal life. After 18 months, Arteriovenous fistula for hemodialysis was closed. By means of PSARP, satisfactory results were reached in adults with delayed anorectal malformation.
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    Pathology, Classification, Clinical Manifestations and Prognosis of Langerhan's Cell Histiocytosis: A Single Center Experience
    (2022) Hasbay, Bermal; Kocer, Nazim Emrah; Kayaselcuk, Fazilet; Canpolat, Emine Tuba; Buyukkurt, Nurhilal; Erbay, Ayse
    Objective: The aim of the study is to raise awareness about clinical features, histopathological and radiological analyzes and treatment details of this rare disease. Methods: A total of 55 Langerhans cell histiocytosis patients, diagnosed between the year 2006 and October 2020 in our department were included in the study. The patients were evaluated in terms of age, gender, tumor localization, risk groups, treatment modalities, recurrence, and outcome of the disease. Results: Twenty-three out of 55 patients were children and 32 were adults. The ages of the patients were between 7 months and 72 years. Thirty-seven of the cases were male and 18 were female. The most common clinical complaint in both groups was pain and swelling. The duration between the onset of the patient complaints and admission to the hospital varies between 7 days-12 months in children, and 10 days-23 years in adults. Forty-three of the cases had single organ involvement and 12 had multiorgan involvement. The most frequently affected organ in both groups was bone. Forty of the 55 patients had follow-up data and the treatment modalities are as follows: Nine patients radiotherapy, 8 patients chemotherapy+steroid, 7 patients chemotherapy, 2 patients chemotherapy+radiotherapy+steroid, 1 patient steroid, 2 patients chemotherapy+radiotherapy. Eleven patients were followed up without additional treatment after surgery. Median follow-up from the time of biopsy was 45.9 months in children and 41.9 months in adults. Conclusions: As a result, diagnosis requires a high degree of suspicion and final diagnosis is based on the histological examination of the lesions and biopsies.
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    Is the Game Over or Starting Again? The Role of the Transplant Team in Genetic Counseling for Adult Sickle Cell Disease Recipients
    (2017) Aytan, Pelin; Gereklioglu, Cigdem; Yeral, Mahmut; Korur, Asli; Asma, Suheyl; Kozanoglu, Ilknur; Ozdogu, Hakan; Boga, Can; 0000-0002-5086-5593; 0000-0002-5268-1210; 0000-0001-5335-7976; 0000-0002-8902-1283; 0000-0002-2553-7715; 0000-0002-9680-1958; 0000-0002-9580-628X; 27956368; AAD-5616-2021; AAE-1241-2021; AAL-6544-2020; ABC-4148-2020; AAI-7831-2021; AAD-5542-2021; AAE-3833-2019; AAD-6222-2021