Tıp Fakültesi / Faculty of Medicine

Permanent URI for this collectionhttps://hdl.handle.net/11727/1403

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    Asymptomatic giant congenital left atrial aneurysm
    (2019) Yakut, Kahraman; Varan, Birgul; Erdogan, Ilkay; 31559732
    Congenital aneurysm of the left atrial appendage can be caused by congenital dysplasia of the pectinate muscles and may be accompanied by a congenital absence of the pericardium. Symptoms generally manifest after two decades and the most common symptom is atrial arrhythmia in the form of atrial fibrillation / flutter. A four year-old patient with no symptoms underwent an echocardiographic examination for the investigation of a heart murmur. Echocardiographic examination revealed a large cystic lesion occupying the left hemithorax and compressing the left ventricle. The patient was referred to our center. The lesion caused displacement of the heart rightward behind the sternum which made the examination difficult. We aimed to present this rare case of giant left atrial appendage aneurysm in the light of current literature.
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    Distribution of Dynamic Forces on Patient Specific Vascular Model:Application of computational Hemodynamics
    (2015) Kiziltan, Erhan
    Objective: Recent advances in computerized image processing made the early diagnosis and elective invasive treatment of vascular pathologies possible. However, studies state that the complication rates of elective procedures are higher thatn that the of untreated cases. And, making the decision between protection from life threatening complications and unnecessary interventions is a controversial issue. Therefore, recent studies put emphasis on multidisciplinary motivation,; consequently "computational fluid dynamics" took place in medical simulations. With the aim of setting up hemodynamic forces were discussed in vascular models. Methods: Three dimensional distribution of hmodynamic forces in aneurisam and stenotic models were computed by uisng two different patient specific simulations which were constructed on two different vessel models of "parametric" and "realistic" approaches. Results: The results were consistent with almost all common practical knowledge. Continuity and Bernoulli's laws imply that a fluid moving through a wide vessel must move more quickly when the vessel narrows and the pressure decreases gradually. The relation between vessel geometry and velocity vectors in maintained laminor flow conditions was demonstrated. The impacts of radial forces and vessel wall structure on spatial distribution of the displacement in vessel geometry were also shown. Additionally spatial distribution of the axial force of "wall shear stress" which was recently suggested to be a hightly reliable measure was evaluated. Conclusion: Patient specific simulations that are belived to be the core of the future project of "clinical diagnostic expert systems" will be an important tool; in prescribing patient specific treatment and in the assessment of complications risks.