Tıp Fakültesi / Faculty of Medicine
Permanent URI for this collectionhttps://hdl.handle.net/11727/1403
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Item Can We Use Red Cell Distribution as A Marker of Mortality in Acute Myocardial Infarcts?(2015) Yilmaz, Muhittin Serkan; Isik, Bahattin; Kavalci, Cemil; Salt, Omer; Yel, Cihat; Demirci, Burak; Yilmaz, Fevzi; Durdu, Tamer; Ongar, Murat; Ozdemir, Metin; 0000-0003-2529-2946; AGG-1308-2022Introduction: Red cell distribution width (RDW) is elevated in ischemic diseases and it is reported that this elevation is associated with mortality in this process. In this study, it is aimed to investigate the place of Red cell distribution width in the diagnosis of myocardial infarction and short-term effect on mortality in the patients presenting with chest pain. Materials and methods: The study was performed retrospectively between 1 July 2013 - 31 December 2013. Age, gender, Red cell distribution width, the affected cardiac region, and cardiac mortality levels of the patients with chest pain who were included in the study were examined. In the descriptive statistics of data; mean, standard deviation, and frequency ratio values were used. In the analysis of quantitative data, Mann-Whitney U test was used. Results were evaluated at 95% confidence interval, significance were evaluated at p <0.05. Results: The median age of patients with Acute myocardial infarction was 69 (Range = 65) and 230 of whom (68.9%) were male) in the study. Red Cell Distribution Width was significantly higher in the group with diagnosis of Acute myocardial infarction (p <0.05). The most frequently seen myocardial infarctus type was anterior myocardial infarction (23.8%) whereas hypertension has been found to be accompanied. Red Cell Distribution Width was significantly higher in the patients who died with a diagnosis of Acute myocardial infarction. Conclusion: As a result, the Red cell distribution width level, can be considered as statistically significant in patients with Acute myocardial infarction and is a parameter that may be associated with mortality.Item The Correlation of TWEAK Level And with Involved Area on MRI in Stroke(2017) Yilmaz, Muhittin Serkan; Yilmaz, Murat; Isik, Bahattin; Yel, Cihat; Kavalci, Cemil; Demirci, Burak; Inan, Selim; Kavak, Rasime Pelin; Balamir, Ilhan; Turhan, Turan; 0000-0003-2529-2946; 0000-0001-6658-7260; AGG-1308-2022; AAD-2829-2021; ABG-1934-2020The aim of this study was to value of TWEAK protein in stroke diagnosis and the correlation between Tweak level and lesion size on diffusion MRI in patients admitted to emergency department for acute stroke. Our study was prospectively conducted in a group of patients diagnosed with stroke in the emergency department and a control group between 1 June 2014 and 31 August 2014. Age, sex, vital parameters, comorbid conditions, neurological deficit level, Tweak level, and involved volume on D-MRI were analyzed. Age, sex, vital parameters, comorbid conditions, and Tweak levels were compared between the patient and control groups. Tweak level was compared with neurological deficit and diffusion on D-MRI imaging in the patient group. The results were evaluated in a confidence interval of 95% and at a significance level of p<0.05. There were no significant differences between both groups with respect to age and sex distribution. The median Tweak level of the patient group was significantly higher (912.1 pg/ml vs 808.3 pg/ml, p<0.05). In the patient group NIHSS score had a positive correlation to MRI lesion size (p<0.05) but not to Tweak level (p>0.05). There was no correlation between Tweak level and the involved area on diffusion MRI (p>0.05). In conclusion, Tweak appears as a parameter that can be used in patients with a clinical presentation consistent with Stroke. It can be used for diagnostic purposes when cranial CT does not support the diagnosis or for supporting diagnosis when D-MRI is not available.Item Importance of Red Blood Cell Distribution Width (RDW) in Patients with Upper Gastrointestinal Haemorrhage(2016) Isik, Bahattin; Yilmaz, Muhittin Serkan; Yel, Cihat; Kavalci, Cemil; Solakoglu, Gorkem Alper; Ozdemir, Metin; Ongar, Murat; Demirci, Burak; https://orcid.org/0000-0003-2529-2946; 26819158; AGG-1308-2022Objective: To explore the effect of red blood cell distribution width levels on the diagnosis and management of upper gastrointestinal haemorrhage. Methods: The retrospective study was conducted at Ankara Numune Education and Research Hospital, Turkey, and comprised record of patients diagnosed with upper gastrointestinal haemorrhage from January 1, 2013, to December 31, 2013. Factors analysed were age, gender, red blood cell distribution width level, admission haemoglobin and haematocrit levels, endoscopy findings classified according to the Forrest system, comorbid diseases, use of medications, unhealthy habits like alcohol usage and smoking, and mortality rate. Results: Of the 147 patients, 93(64%) were men. The overall median age of the sample was 60 years. Besides, 117(79.6%) patients had comorbid diseases, of which hypertension 56(38.4%) was the most common. A total of 24(16.8%) patients were using antiplatelet or anticoagulant drugs, while 30(20.5%) were on non-steroidal anti-inflammatory drugs. Peptic ulcer in 128(87.1%) patients was the most common cause of haemorrhage. The median red blood cell distribution width level of the study population was 15.25% which was significantly higher compared to the reference values (p<0.05).. In contrast, haemoglobin 9.55% (3.7) and haematocrit 28.75% (10.8) were significantly lower (p<0.05). Mortality rates were significantly higher in patients with higher red blood cell distribution width values (p<0.05). Conclusion: Red blood cell distribution width levels were higher during the acute phase of upper gastrointestinal haemorrhage.