Tıp Fakültesi / Faculty of Medicine
Permanent URI for this collectionhttps://hdl.handle.net/11727/1403
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Item Neuroendocrine Tumour of the Gallbladder Diagnosed after Cholecystectomy(2022) Tasci, Halil Ibrahim; Coskunoglu, Esra Zeynep; Turk, Emin; Karagulle, Erdal; 0000-0003-2269-4798; AAJ-2989-2021Gallbladder cancer is a rare but aggressive malignancy. Neuroendocrine tumour of the gallbladder make up 2-3% of all the gallbladder tumour. A 67-year female patient underwent laparoscopic cholecystectomy because of symptomatic cholelithiasis and the histopathology revealed a neuroendocrine tumour of the gallbladder, stage pT2a. The patient's imaging study for metastasis workup were normal. A radical cholecystectomy procedure was planned as the tumour stage was pT2a. Postoperative chemotherapy and/ or radiotherapy were recommended. The patient, who had comorbidities, was refused both surgery and other treatment alternatives. The patient's one-year clinical, laboratory, and radiological follow-up did not reveal any findings of recurrence or metastasis. There is no standardised staging system for neuroendocrine tumours of the gallbladder since the number of such cases is quite limited. Guidelines are also insufficient. Multi-centred and large studies are needed in order to develop standardisation in treatment, prognosis, and factors affecting survival.Item A Rare Case: Primary Mucinous Cystic Neoplasm Of The Gallbladder(2021) Tasci, Halil Ibrahim; Erinanc, Ozgur Hilal; Turk, Emin; Karagulle, ErdalCystic lesions originating from the gallbladder are very rare. Mucinous cystic neoplasms of the liver and biliary system principally occur in the liver, followed by the extrahepatic biliary system. Only a few case reports were reported primarily in the gallbladder. A 63-year-old woman was admitted to our hospital with complaints of pain in the right upper abdomen, increasing after meals, and abdominal discomfort. A laparoscopic cholecystectomy was performed. Macroscopically, the cyst was localized in the serosa of the fundus. Based on immunohistochemical examination, the cyst was diagnosed as primary mucinous cystic neoplasia of the gallbladder. Although it is very rare, mucinous cystic neoplasia should be kept in mind when dealing with cystic lesions of the gallbladder. Due to serious associated problems such as the risk of malignant transformation or bile duct obstruction, particularly in larger cysts, a cholecystectomy is mandatory.