Tıp Fakültesi / Faculty of Medicine

Permanent URI for this collectionhttps://hdl.handle.net/11727/1403

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Author: search.filters.author.Soylev, Gozde Ozcansearch.filters.applied.f.rights: search.filters.rights.info:eu-repo/semantics/closedAccess

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    Assessment of Subclinical Atherosclerosis in Vitamin D Deficiency
    (2019) Aydin, Elcin; Altin, Cihan; Soylev, Gozde Ozcan; Tekindal, Mustafa Agah; Agildere, Muhtesem; 30300321; AAB-5802-2020
    Purpose Patients with vitamin D deficiency (VDD) have potential to have increased cardiovascular morbidity and mortality. In this study, we aimed to discover the findings of early atherosclerosis in patients with VDD by measuring carotid intima-media thickness (CIMT) and epicardial fat thickness (EFT). Materials and Methods The study population includes 52 patients with VDD (n = 30 [57% female], mean +/- SD age 54.28 +/- 8.77 years, mean +/- SD serum 25-hydroxyvitamin D (25 [OH] D) 11 +/- 2.4 ng/mL) and 82 participants for control group (n = 52 [63.4% female], mean +/- SD age 56.40 +/- 7.90 years, mean +/- SD serum (25 [OH] D) 53 +/- 4.2 ng/mL) who have no cardiovascular disease. Carotid intima-media thickness was assessed by using ultrasonography, and EFT was measured on the free wall of the right ventricle at end diastole from the parasternal long-axis views by standard transthoracic 2-dimensional echocardiography. Results Both CIMT and EFT were significantly higher in patients with VDD compared with controls (0.75 +/- 0.16 mm vs 0.68 +/- 0.21 mm, P < 0.05, and 0.66 +/- 0.15 cm vs 0.56 +/- 0.15 cm, P < 0.001). Conclusions Patients with VDD seem to have increased CIMT and EFT, which are predictors of atherosclerotic process. Further studies are needed to confirm these results.
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    Vertebroplasty in Vertebral Compression Fractures: Single Institute Experience with 49 Cases
    (2017) Altınel, Faruk; Soylev, Gozde Ozcan; Tuncali, Bahattin; Altinors, Mehmet Nur; 0000-0002-7898-2943; 0000-0001-8742-5543; 0000-0002-8326-3900; AAJ-7840-2021; AAJ-4917-2021; AAJ-5382-2021
    Objective: Percutaneous vertebroplasty (PVP) is the preferred treatment option for vertebral compression fractures (VCF). In this study, the efficacy and complications of PVP were investigated among 49 patients with VCF. Methods: Forty-nine patients with VCF due to osteoporosis, trauma, osteolytic bone tumors, metastases or leukemia who were admitted to our hospital between 2012 and 2015 and treated with PVP were included in the study. In patients' preoperative and postoperative evaluation, a visual analogue scale (VAS) was used to assess back and leg pain, preoperative routine lumbar vertebral radiography was used for fracture morphology, lumbar magnetic resonance imaging was performed, and the segmental kyphotic angle, vertebral corpus compression rate, polymethylmethacrylate (PMMA) cement volume, and diffusion of PMMA were recorded. Results: Preoperative and postoperative VAS scores were 8.6 +/- 0.9 vs. 1.13 +/- 1.1 (p < 0.01). The approximate compression rate was 24.72 +/- 13.99 %, the ratio of approximate restoration height was 3.47 +/- 5.36, and the mean kyphosis angle was 7.35 +/- 6.81 degrees. The mean pre- and postoperative values of vertebral height were 1.83 +/- 0.39 cm vs1.88 +/- 0.36 cm (P <.01). Conclusion: In this study, preoperative pain in patients with VCF prominently diminished in the postoperative early and late phase. After PVP, vertebral height showed a subtle increase.