Tıp Fakültesi / Faculty of Medicine

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Author: search.filters.author.Koksal, Burcu TahireSubject: search.filters.subject.25-hydroxyvitaminD

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    Serum Vitamin D Levels in Children with Recurrent Respiratory Infections and Chronic Cough
    (2016) Ozdemir, Beril; Koksal, Burcu Tahire; Karakas, Nazmi Mutlu; Tekindal, Mustafa Agah; Ozbek, Ozlem Yilmaz; 0000-0003-2974-9579; 0000-0003-4286-7086; 0000-0001-9580-7656; 0000-0002-4060-7048; 26821547; AAJ-2034-2021; HKW-0623-2023; AAX-3831-2020; AAF-2109-2021; U-9270-2018
    Objectives To evaluate serum vitamin D levels in cases of recurrent respiratory infections and chronic cough and to investigate the effect of vitamin D therapy on recurrence of the diseases. Methods This prospective observational study was performed by comparing serum vitamin D levels in children with recurrent respiratory infections, chronic cough and healthy children. One-hundred-one children with chronic cough, ninety-eight children with recurrent respiratory infections and one-hundred-twenty-four healthy children were enrolled in the study. A structured questionnaire was completed to collect data on demography, diet, duration of breastfeeding, vitamin D supplementation and family history for allergic diseases. In patients with low serum vitamin D levels (<20 ng/ml), vitamin D therapy was administered in addition to conventional treatment for the diseases. Patients were followed up for 6 mo and their complaints were evaluated. Results Mean serum 25( OH) vitamin D level in the recurrent respiratory infections group was 11.97 +/- 4.04 ng/ml, chronic cough group was 13.76 +/- 4.81 ng/ml and control group was 31.91 +/- 18.79 ng/ml. Comparison of serum 25( OH) vitamin D levels between the study groups revealed a statistically significant difference ( p < 0.05). 25( OH) D deficiency in children was associated with increased frequency of recurrent respiratory infections and chronic cough. Conclusions To conclude, administration of supplementary vitamin D may be useful in the treatment and preventation of recurrent respiratory infections and chronic cough.