Tıp Fakültesi / Faculty of Medicine

Permanent URI for this collectionhttps://hdl.handle.net/11727/1403

Browse

Filters

20203

Settings

Author: search.filters.author.Gunesli, Aylinsearch.filters.applied.f.language: search.filters.language.tur

Search Results

Now showing 1 - 3 of 3
  • No Thumbnail Available
    Item
    Comparison of carotid elasticity and distensibility between patients with end-stage renal disease and healthy volunteers
    (2020) Gunesli, Aylin; Torer, Nihan Tekkarismaz
    Purpose: The incidence of cardiovascular events increased in patients with end-stage renal disease, but it is not clear how renal failure affects carotid arteries. The aim of this study is to evaluate this affect. For this purpose, the elasticity and distensibility which are markers of subclinical carotid atherosclerosis were measured and compared in patients with end-stage renal disease and healthy population. Materials and Methods: The study was planned as crosssectional. A total of 119 subjects (61 patients and 58 control) were enrolled into the study. Carotid elasticity and distensibility were measured and compared between the groups. In addition, we investigated whether there was a significant correlation between the duration of dialysis and carotid elasticity and distensibility. Results: Carotid elasticity and distensibility were significantly lower in the patient group than in the control group (0.12 +/- 0.02 vs. 0.23 +/- 0.04, p < 0.001, and 7.47 +/- 0.51 vs. 9.42 +/- 0.73, p < 0.001, respectively). Correlation analysis revealed a significant positive correlation between the duration of dialysis and carotid elasticity and distensibility (r = -0.783, p < 0.001 ve r = -0.385, p = 0.002, respectively). Conclusion: Carotid elasticity and distensibility decreased in patients with end-stage renal disease. These results may suggest an increased risk of subclinical atherosclerosis in the carotid arteries in this patient group and may indirectly suggest that the increase in the risk of cerebrovascular event is caused by atherosclerosis in the carotid arteries.
  • No Thumbnail Available
    Item
    Simultaneous balloon angioplasty and stent implantation in supraaortic multiple stenosis
    (2020) Gunesli, Aylin; Akgul, Erol
    Purpose: The aim of this study was to evaluate the success and complications of endovascular treatment in supraaortic multiple stenotic lesions Materials and Methods: The study was planned as a retrospectively. The records of patients who underwent percutaneous interventional treatment for multiple stenosis in the supraaortic vessels between January 1, 2004 and December 31, 2009 were reviewed. Percutaneous endovascular intervention was decided with doppler ultrasonography, magnetic resonance imaging, computed tomography or digital subtraction angiography provided that more than 50% stenosis was detected in the supraaortic vessels. Patients with at least 2 severe stenosis who underwent multiple interventional procedures in one session were included in the study. Results: A total of 34 patients (mean age 60.4 +/- 12.5 years and 6 female (17.4%)) were included in the study. A total of 74 lesions were treated in 34 patients. Stents were used in all procedures. No mortality or serious morbidity was observed during follow-up. The technical success of the procedure was 100%. Restenosis was observed in 4 patients (11.7%) at a mean follow-up of 29.5 +/- 18.3 months. Three of these patients were re-treated. Conclusion: According to the results of our study, endovascular intervention can be safely performed in occlusive atherosclerotic vascular disease of the supraaortic branches. Mortality and morbidity of this treatment is very low. In patients with restenosis during follow-up, re-intervention can be performed safely. If multiple lesions are present in the same patient group, multiple interventions are a safe treatment option.
  • No Thumbnail Available
    Item
    Comparison of Epicardial Fat, Carotid and Femoral Intima-Media Thicknesses Between Hypertensive, Pre-Hypertensive and Control Groups
    (2020) Gunesli, Aylin; Yilmaz, Mustafa; 0000-0002-2557-9579; S-6973-2016
    Objective: The aim of this study was to evaluate whether pre-hypertension is a risk factor for cardiovascular events. For this reason epicardial fat thickness (EFT), carotid intima-media thickness (CIMT) and femoral intima-media thickness (FIMT), known as markers for subclinical atherosclerosis and cardiovascular risks were measured and compared among the pre-hypertensive, hypertensive and control groups. Material and methods: This cross-sectional study included 57 healthy controls (group 1), 58 pre-hypertensive patients (group 2) and 56 hypertensive patients (group 3). Pre-hypertension is defined as systolic blood pressure (SBP) 120-140 mm Hg and diastolic blood pressure (DBP) 80-90 mm Hg. Hypertension is defined as SBP>140 mm Hg and/or DBP>90 mm Hg. EFT, CIMT and FIMT were measured and compared among these groups. Results: There was a statistically significant difference among the groups in terms of EFT and CIMT (p<0.001, for both comparison). In addition there was a statistically significant difference between groups 2 and 1, and between groups 3 and 2 in terms of EFT and CIMT (p<0.001, for all comparisons). When we compared the all groups in terms of FIMT, we found a statistically significant difference (p<0.001). There was a statistically significant difference between groups 3 and 2 (p=0.001). However, there was not a statistically significant difference between groups 2 and 1 (p=0.773). Conclusion: These results may indirectly suggest that subclinical atherosclerosis and cardiovascular risks may be increased in pre-hypertensive patients. However, atherosclerosis in the carotid arteries may be affected by lower blood pressure than the femoral arteries.