Tıp Fakültesi / Faculty of Medicine

Permanent URI for this collectionhttps://hdl.handle.net/11727/1403

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2014 - 20173

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Author: search.filters.author.Findik, Melihasearch.filters.applied.f.rights: search.filters.rights.info:eu-repo/semantics/closedAccess

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    X-Ray Quiz: Ankle Sprain
    (2014) Kilicli, Elif; Findik, Meliha; Kavalci, Cemil; https://orcid.org/0000-0003-2529-2946; AGG-1308-2022
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    Serum Neutrophil Gelatinase-Associated Lipocalin Levels In Early Detection Of Contrast-Induced Nephropathy
    (2016) Muratoglu, Murat; Kavalci, Cemil; Kilicli, Elif; Findik, Meliha; Kayipmaz, Afsin Emre; Durukan, Polat; https://orcid.org/0000-0002-9586-7509; https://orcid.org/0000-0003-2529-2946; 27439687; AAK-2079-2021; AGG-1308-2022; AAC-2597-2020
    Purpose: The purpose of this study was to investigate the role of serum neutrophil gelatinase-associated lipocalin (NGAL) levels in the early detection of contrast-induced nephropathy (CIN). Methods: This prospective study enrolled 74 patients undergoing abdominal tomography with contrast (1 November 2014 - 28 February 2015). Demographic properties (age and sex), symptoms and CT examination results were analysed. Sodium, potassium, urea, creatinine and NGAL levels were measured at 0th, 6th, and 72nd hours. P value < 0.05 was considered statistically significant. Results: CIN developed in 16.2% of the study patients. The mean age was significantly higher in the patients who developed CIN (p<0.05). No significant correlation existed between the occurrence of CIN and patient gender (p>0.05). Urea levels did not differ significantly between the groups at 0th and 6th hours (p>0.05) but was significantly higher in the patients with CIN at 72nd hour (p<0.05). Urea levels did not change significantly over time in the entire group (p>0.05). Creatinine level was not significantly different between the groups (p>0.05) but increased significantly over time (p>0.05). There were no significant differences between the groups with respect to NGAL levels at 0th and 72nd hours (p>0.05) whereas the group with CIN had a significantly higher NGAL level at 6th hour (p<0.05). A NGAL level of 668 mg/dL at 6th hour had a sensitivity of 100%, specificity of 95%, positive predictive value of 80% and negative predictive value of 100% for the detection of CIN. Conclusion: NGAL may be a useful marker for the early detection of CIN.
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    Red Blood Cell Distribution Width Increases During Infection in Renal and Liver Graft Recipients
    (2017) Kayipmaz, Afsin Emre; Findik, Meliha; Kavalci, Cemil; Akdur, Aydincan; Moray, Gokhan; Haberal, Mehmet; 0000-0002-3462-7632; 0000-0003-2529-2946; 0000-0002-8726-3369; 0000-0003-2498-7287; 26767568; AAJ-8097-2021; AGG-1308-2022; AAA-3068-2021; AAC-2597-2020; AAE-1041-2021
    Objectives: Organ transplant is an effective treatment for patients with end- stage renal and hepatic failure. Increased use has introduced more emergency department admissions of infectious origin after transplant. Because infections usually manifest with simple complaints and fever, emer gency physicians need laboratory tests and radiologic imaging procedures to quickly detect the presence and source of infection. Our aim was to analyze fever-related emergency admissions of renal and hepatic graft recipients and determine whether admitted patients had increased red blood cell distribution width and mean platelet volume levels. Materials and Methods: We reviewed the medical records of renal and hepatic graft patients who presented to our emergency department with fever during a 4-year period. Our analyses included 150 patients in which complete blood count and C-reactive protein results were available and the source of infection was determined. We compared results with a control group of 150 transplant patients without any infectious findings. Results: In the 150 solid-organ graft recipients who presented to our emergency department with fever, significant differences were observed versus control patients with respect to white blood cell count, neutrophil-to-lymphocyte ratio, red blood cell distribution width, mean platelet volume, and C-reactive protein levels (P <.05). We determined that C-reactive protein levels, red blood cell distribution width, mean platelet volume, and lymphocyte count were independent indicators of infection on multiple logistic regression analyses. We also determined that red blood cell distribution width had a specificity of 94% and a sensitivity of 26%. Conclusions: We found a significantly higher red blood cell distribution width in emergency admissions of infectious origin of renal and hepatic graft recipients than in the control group (P <.001), suggesting that this measurement is a suitable marker of infection for the emergency setting by virtue of rapid availability of test results and lack of extra costs.