Tıp Fakültesi / Faculty of Medicine
Permanent URI for this collectionhttps://hdl.handle.net/11727/1403
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Item Comparative Findings Between Ga-68-PSMA and F-18-FDG PET/CT for Hepatocellular Carcinoma(2020) Erhamamci, Seval; Aslan, Nesrin; 0000-0001-5016-4650; 33094578We have reported here the case of a 69-year-old man who presented with spinal cord compression due to bone metastases as the first manifestation of hepatocellular carcinoma (HCC). For the initial staging, the patient underwent F-18-fluorodeoxyglucose (FDG) positron emission tomography/computerized tomography (PET/CT) imaging, which demonstrated mild F-18-FDG uptake in the multiple expansile osteolytic bone lesions, but no remarkable atypical F-18-FDG uptake in the liver lesion on low-doses CT. An additional PET/CT scan was performed to evaluate the prostate-specific membrane antigen (PSMA) expression, which has recently been reported to be a potential biological marker in a variety of tumors including HCC. High PSMA uptake was recorded in both the metastatic bone lesions and the primary liver lesion/tumor by the Ga-68-PSMA PET/CT.Item Primary Hepatocellular Carcinoma With Intense Ga-68-PSMA Uptake But Slight F-18-FDG Uptake on PET/CT Imaging(2020) Erhamamci, Seval; Aslan, Nesrin; 31977478Ga-68-PSMA PET/CT imaging is an emerging imaging modality in prostate cancer. PSMA expression is also reported for nonprostate malignancies, including primary hepatocellular carcinoma. Herein, we present a case of a 74-year-ald man with recently diagnosed hepatocellular carcinoma who was referred for F-18-FDG PET/CT imaging for initial staging. The patient underwent F-18-FDG PET/CT as part of staging procedure; he also underwent Ga-68-PSMA PET/CT. PET/CT images revealed only slight F-18-FDG uptake in the liver lesion, but intense Ga-68-PSMA uptake, without any metastatic lesion seen elsewhere in the body.