Tıp Fakültesi / Faculty of Medicine
Permanent URI for this collectionhttps://hdl.handle.net/11727/1403
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Item Increased Frequency of Gallbladder Stone and Related Parameters in Hemodialysis Patients(2014) Genctoy, Gultekin; Ayidaga, Sevgul; Ergun, Tarkan; Lakadamyali, Hatice; Erbayrak, Mustafa; Sezer, Siren; https://orcid.org/0000-0002-5145-2280; https://orcid.org/0000-0002-6165-2569; https://orcid.org/0000-0002-7326-8388; 24918131; AAJ-5551-2021; JVN-6452-2024; JYQ-2550-2024Background/Aims: The prevalence of gallbladder stone (GBS) is shown to be increased in some studies in patients with chronic kidney disease (CKD). Nevertheless, some other studies did not confirm these findings. The controversial results about the prevalence of GBS in hemodialysis (HD) patients demand new studies to search GBS prevalence and associating risk factors in HD patients. In the present study, we aimed to investigate GBS prevalence and risk factors in our HD patients. Materials and Methods: A total of 104 HD and 149 control patients were involved. Complete physical examinations, including measurements of dry body weight and height, were done. Abdominal ultrasonography was conducted by the same experienced radiologist. Blood samples were drawn via venipuncture from the study participants after they had fasted overnight just before a midweek hemodialysis session for laboratory examinations. Results: The prevalence of GBS in HD patients was 34.6 % (36/104), and that was significantly higher than that of control group 12.9% (17/149; p=0.0001). In all study participants (HD patients and control group), patients with GBS were older than patients with no GBS (63.2 +/- 14.2 vs 53.7 +/- 16.7; p=0.0001). However, in HD patients, mean age was similar in patients with GBS and no GBS (64.3 +/- 13.8 vs 60.1 +/- 16.6; p>0.05). Patients with GBS had a higher prevalence of units of blood transfusions than patients with no GBS in hemodialysis patients (2.0 +/- 2.9 vs 0.9 +/- 1.3; p=0.047) Conclusion: The present study showed an increased prevalence of GBS in HD patients compared to healthy controls. The number of blood transfusions and autonomic neuropathy may be responsible for the increased prevalence of GBS in HD patients.Item Cystic Meningioma Showing Peripheral Rim Enhancement without Mural Nodule(2015) Ergun, Tarkan; Torun, Ebru; Lakadamyali, Hatice; 0000-0002-6165-2569; 25287819; JVN-6452-2024Item Periaortic Fat Tissue: A Predictor of Cardiac Valvular Calcification, Malnutrition, Inflammation, and Atherosclerosis Components in Hemodialysis Patients(2015) Genctoy, Gultekin; Eldem, Olcay; Ergun, Tarkan; Arikan, Serap; 0000-0002-5145-2280; 0000-0001-5752-3812; 25940595; AAJ-5551-2021; AAM-4084-2021; AAJ-1289-2021Cardiac valvular calcification (CVC) in end-stage renal disease is shown to be a component of malnutrition, inflammation, atherosclerosis, calcification (MIAC) syndrome. Thoracic periaortic fat tissue (T-PAFT) is shown to be increased in patients with end-stage renal disease (ESRD), and has positive correlation with MIAC. Negative correlation between CVC and vitamin D is shown in hemodialysis (HD) patients. In this study, we investigated a relationship between body composition, T-PAFT, metabolic and inflammatory parameters, and CVC in HD patients. Seventy-six HD patients (49M) were included. CVC is defined as bright echoes of >1mm on one or more cusps on echocardiography. Results were expressed as the number of calcified valves (0,1,2). Calcium, phosphorus, parathyroid hormone (PTH), C-reactive protein (CRP), albumin and 25-hydroxy vitamin D levels were studied from predialysis blood samples. T-PAFT was calculated using a method with manual definition of borders on images from multislice computed tomography. Basal metabolic rate, muscle mass, total and truncal fat mass were measured by bioimpedance analysis. There were 65.8% of patients who had CVC. Patients with CVC were older (63.5 +/- 14.6 +/- 17, P=0.02). T-PAFT (1599 +/- 596, 739.7 +/- 179mm(2), P=0.001) and CRP (15.8 +/- 11; 11.1 +/- 13.2mg/dL; P=0.04) were higher in the group with CVC. T-PAFT had positive correlations with CRP, MIAC, body mass index (BMI) and number of calcified valves, negative correlation with left ventricular ejection fraction, and no correlation with albumin, calcium, phosphorus, and PTH. The logistic regression analysis revealed that T-PAFT was a significant predictor of CVC. In this study, T-PAFT showed a positive correlation with inflammation, CVC, and MIAC score in HD patients. T-PAFT was a significant predictor of CVC.Item High riding jugular bulb: Is it an etiological factor for benign paroxysmal positional vertigo?(2021) Çoban, Kuebra; Kansu, Leyla; Ergun, Tarkan; Aydin, ErdincIntroduction: High jugular bulb (HJB) is usually discovered incidentally; however, it may interfere with inner ear structures such as vestibular aqueduct (VA), facial nerve, and the posterior semicircular canal (PSCC). Objective: The aim is to investigate the incidence of HJB in benign paroxysmal positional vertigo patients with PSCC involvement (PSCC-BPPV). Materials and Methods: The study group included 53 consecutive, PSCC-BPPV patients, diagnosed in our clinic. Following the diagnosis, their high resolution computed temporal bone tomography were performed. The control group consisted of 90 patients, who attended to our clinic for various complaints, and to whom high resolution computed tomography of the temporal bone was conducted. Results: The incidence of HJB in the study group was 41.5% (n = 22). The incidence of ipsilateral HJB in this group was 28.3% (n = 15). The incidence of HJB in the control group was 11.1% (n = 10) (P < 0.001). The closest distance between HJB and PSCC canal in the control and study groups was 1.61 +/- 0.74 mm and 1.17 +/- 0.37 mm, respectively (P = 0.098). Conclusion: The HJB is significantly more frequent in PSCC-BPPV patients. Furthermore, the rate of incidence of HJB in the ipsilateral ears of these patients is significantly higher. Venous hypertension or the turbulence may cause strong pulsations, which influence the detachment of the otoconia into the PSCC.