Tıp Fakültesi / Faculty of Medicine
Permanent URI for this collectionhttps://hdl.handle.net/11727/1403
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Item Embolization of Pulmonary Sequestration with Onyx: An Unusual Application(2014) Gursu, Alper Hazim; Boyvat, Fatih; Varan, Birgul; Erdogan, Ilkay; https://orcid.org/0000-0002-0707-2678; https://orcid.org/0000-0002-6719-8563; https://orcid.org/0000-0001-6887-3033; 24643150; AHI-4502-2022; F-4230-2011; ABB-1767-2021; ABB-2220-2021We report a baby with intralobar pulmonary sequestration who was successfully treated with a new embolization agent, Onyx. A 1.5-month-old female infant was admitted to our hospital with sweating and fatigue. Telecardiography showed cardiomegaly, dextrocardia, and increased pulmonary vascular markings. In thoracic computerized tomography, pulmonary sequestration, right pulmonary hypoplasia, and large collateral arteries were seen. The collateral arteries were originating from the celiac trunk and aorta. Echocardiography revealed enlargement of the left atrium and ventricle and left ventricle systolic dysfunction. Angiography revealed a large feeding artery and three branches originating from the aorta and another feeding artery originating from the celiac trunk. We performed embolization of the feeding arteries and their branches, with coils and Onyx. The procedure was performed without complications, and all feeding arteries were completely occluded. The infant started to gain weight. One year later, the infant's body weight had increased and she had no respiratory problems or signs of congestive heart failure. In this case report, we suggest that embolization with Onyx is a reliable alternative method to surgery for infants with pulmonary sequestration. With future studies, pulmonary sequestration embolization with Onyx may become an acceptable and easy treatment option in pediatric patients.Item A Rare Cardiovascular Finding in Two Cases with Williams Syndrome: Recurrent Coarctation of Aorta(2015) Ari, Mehmet Emre; Erdogan, Ilkay; Varan, Birgul; Ozkan, Murat; 0000-0002-6719-8563; 0000-0001-6887-3033; 0000-0001-7932-1074; ABB-1767-2021; ABB-2220-2021; W-1590-2017Williams syndrome is a genetic disorder caused by multiple gene deletions on chromosome 7. The majority of the cases is sporadic and has typical facial appearance, cardiac anomalies and mental retardation. Cardiovascular anomalies are present in about 80% of the cases, most frequently supravalvular aortic stenosis and pulmonary arterial stenosis. In this article, we report two pediatric cases with a rapidly progressive form of aortic coarctation, each of whom required two surgeries and two percutaneous balloon dilatations within the first five months of life.Item Hypomagnesemia in Pediatric Heart Transplant Patients Treated with Tacrolimus(2018) Erdogan, Ilkay; Gursu, Hazim A.; Varan, Birgul; Ozkan, Murat; Sezgin, Atilla; 0000-0001-6887-3033; 0000-0002-0707-2678; 0000-0002-6719-8563; 27364480; ABB-2220-2021; AHI-4502-2022; ABB-1767-2021Objectives: We aimed to investigate the frequency of hypomagnesemia and urinary magnesium excretion in pediatric heart transplant recipients. Materials and Methods: In this study, 22 pediatric patients who underwent heart transplanted at a single center between March 2014 and April 2015 and who were treated with oral tacrolimus were analyzed prospectively. Serum magnesium, creatinine, and tacrolimus levels and total amount of urinary magnesium excretion were measured. Serum tacrolimus levels were measured 12 hours after the last dose of tacrolimus. Results: Our patient group included 11 boys (50%) and 11 girls (50%) with a mean age of 16.72 +/- 4.78 years. Serum tacrolimus levels were in the therapeutic range, with a mean of 1.48 +/- 0.13 ng/mL (range, 1.2-1.69 ng/mL), mean fractional magnesium excretion was 8.59 +/- 5.9% (range, 3%-22%), and 24-hour urinary magnesium excretion was 90.2 +/- 62.95 mg/d. Hypermagnesuria was assessed in 80% of patients. We found 24-hour urinary magnesium excretion to be higher than normal in 27% of patients. There was no association between serum tacrolimus levels and serum magnesium levels or urinary magnesium excretion. Conclusions: Serum magnesium levels should be periodically measured in pediatric heart transplant patients treated with tacrolimus.