Tıp Fakültesi / Faculty of Medicine

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Author: search.filters.author.Beyaz, SalihSubject: search.filters.subject.Diabetic foot

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    Do diabetic patients who undergo transtibial amputation receive adequate treatment?
    (2019) Beyaz, Salih; 0000-0002-5788-5116; 30946028; M-2609-2013
    AIMS: To determine if patients who undergo below-knee amputation (BKA) for intractable wounds caused by diabetes complications receive adequate treatment before surgery. MATERIALS AND METHODS: The study included a total of 528 patients who underwent transtibial amputation for diabetic foot. All patients were assessed on the basis of duration of preoperative treatment, HbO therapy, negative wound pressure therapy (NPWT), peripheral vascular angioplasty (PVA) treatment, wound cultures, antibiotic medications, consultations with plastic and vascular surgeons, need for hemodialysis treatment, use of anticoagulant treatment as an inpatient, and assessment of blood sugar regulation by an endocrinologist. HbA1c, BUN, Creatinine, ESR, and CRP values attained for preoperative assessment were noted. RESULTS: Eighteen patients (3.5%) received HbO therapy, 35 (67%) NPWT therapy and 347 (65.7%) anticoagulant treatment. Wound cultures were taken in 317 patients (60.5%) and 390 (73.9%) received preoperative antibiotic treatment. 45 (8.6%) patients were assessed by plastic surgeon with 22 (4.2%) subsequently undergoing surgery by the plastic surgeon. Vascular surgeons assessed 163 patients (30.9%) and performed procedures on 45 patients (8.6%). Endocrinologists assessed 316 patients (59.8%) and implemented blood sugar regulation. PVA treatment was performed in 246 patients (466%). Patients who were managed medically for more than 7 days after the initial assessment received more HbO therapy (p=0.037), anticoagulant treatment (p=0.015), IV antibiotics (0.001), blood sugar regulation attempts (p=0.001), and PVA therapy (0.001) and had more cultures taken (p=0.001). These patients also received overall more diagnostic and treatment modalities than those that received definitive surgical intervention within 7 days. CONCLUSIONS: The duration of time patients with diabetes-related foot problems who see orthopedic surgeons for longer periods of time receive more treatment modalities and are referred more often to specialists before transtibial amputation surgery. We believe that delayed presentation is one of the main obstacles prohibiting adequate treatment for these patients.
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    Factors affecting lifespan following below-knee amputation in diabetic patients
    (2017) Beyaz, Salih; Guler, Umit Ozgur; Bagir, Gulay Simsek; 0000-0002-5788-5116; 0000-0002-5375-635X; 0000-0002-5375-635X; 28865844; K-8820-2019; O-7590-2017; AAJ-4844-2021
    Introduction: Untreatable foot problems in diabetics may require lower extremity amputation, which has a high level of patient mortality. This high mortality rate is worse than most malignancies. The present study aimed to identify parameters that can be used to estimate survival in DM patients undergoing below-knee amputations for diabetic foot problems. Materials and methods: A total of 470 patients (299 males, 171 females) with a mean age of 64.32 years who underwent below-knee amputation for diabetic foot problems between 2004 and 2014 were enrolled in the study. The length of time from the operation to time of death was recorded in days. Patient details were obtained, including age during surgery, BMI, oral antidiabetic and insulin usage, dialysis therapy history, lower extremity endovascular intervention, previous amputation at the same extremity, the need for stump revision surgery during follow-up, and above-knee amputation at the same site. Biochemical test results of pre-operative HbAl c, ESR, and levels of CRP, BUN, and creatinine were also obtained. Results: A total of 333 patients (70.9%) died and 137 (29.1%) survived post-surgery. Survival rates were 90% in the first 7 days, 84% in the first 30 days, and 64% after the first year. Patient median life expectancy post-surgery was 930 106 days. Hemodialysis treatment (p = 0.001), endovascular intervention (p = 0.04), sex (p = 0.004), age (p = 0.001), BUN level (p = 0.001), and duration of insulin use (p = 0.003) were shown to be effective predictors of mortality. Conclusions: Life expectancy is low (<3 years) in DM patients requiring below-knee amputations for untreatable foot problems. Survival could be predicted by duration of insulin use, age, sex, and renal insufficiency. Level of evidence: Level IV, Therapeutic study. (C) 2017 Turkish Association of Orthopaedics and Traumatology. Publishing services by Elsevier B.V.