Tıp Fakültesi / Faculty of Medicine

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Author: search.filters.author.Bal, NebilSubject: search.filters.subject.Prostate

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    Metachronous Prostate Metastasis of Renal Cell Carcinoma: Case Report and Review of the Literature
    (2016) Guler, Ozan Cem; Bal, Nebil; Onal, Cem; https://orcid.org/0000-0001-6908-3412; https://orcid.org/0000-0002-2742-9021; 26739102; AAC-5654-2020; HOC-5611-2023
    Secondary tumors of the prostate are very rare, and only a few reports of prostate metastasis originating from renal cell carcinoma (RCC) have been published. The reported 5-year survival rate has been approximately 35% for patients who underwent nephrectomy and surgical resection of a solitary metastasis. Immunohistochemical analysis showed that CD10 and vimentin positivity were helpful for distinguishing clear cell RCC from other renal tumors. We report a case with delayed metachronous metastasis of RCC to the prostate, which clinically mimicked benign prostatic hyperplasia or prostate cancer, treated with transurethral resection and palliative radiotherapy. (C) 2016 Elsevier Inc. All rights reserved.
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    Inflammatory Myofibroblastic Tumor of the Prostate
    (2016) Kocer, Nazim Emrah; Bal, Nebil; Gul, Umit; Aydin, Hakan
    Inflammatory myofibroblastic tumors (IMT) of the prostate are very rare lesions that may mimic sarcomas and spindle carcinomas both clinically and histopathologically. The case presented here is a 63-year-old patient, with normal prostate specific antigen levels and a chronic history of complaints, who underwent to suprapubic prostatectomy due to the infravesical obstruction symptoms that are resistant to medical therapy. Histopathological examination of the excision material revealed a well demarcated spindle cell lesion with focal nuclear polymorphism, hyperchromasia, mononuclear inflammatory infiltration and myxoid areas. Mitosis was rare. Immunohistochemically smooth muscle actin and vimentin were positive, anaplastic lymphoma kinase-1 was focal positive, S-100 and pancytokeratin were negative. The lesion was diagnosed as an inflammatory pseudotumor. Differential diagnosis of the IMT from malignant spindle cell tumors of the prostate is crucial to prevent overtreatment.