Tıp Fakültesi / Faculty of Medicine
Permanent URI for this collectionhttps://hdl.handle.net/11727/1403
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Item Investigation of HIV/AIDS Knowledge Levels and Approaches to the Disease of Başkent University Faculty of Medicine, Dentistry and Engineering Students(2023) Sari, Nuran; Bilgic, Suveyda; Aydogan, Doga; Akici, Nur Ilayda; Yavuz, Esma Yagmur; Kuscu, Nur Selin; Ardebili, Yasaman; Colak, Meric Yavuz; Azap, Ozlem Kurt; 0000-0002-3171-8926; 0000-0002-0294-6874; 0009-0000-4043-3765; 0000-0002-3165-4520; AAK-4089-2021; AAA-4360-2021Introduction: The number of HIV/AIDS patients is increasing in the world and in our country. It is thought that university students play an important role in developing social awareness necessary for the control of infectious diseases. This study aims to investigate the knowledge level of university students, determine their attitudes towards the disease, and evaluate their behavioral patterns to provide guidance for future studies, training and practices.Materials and Methods: Our research is a descriptive, cross-sectional field study. A survey including questions about HIV/AIDS trans- mission routes, disease recognition, attitudes and behaviors was prepared and delivered to the students of our university's faculty of medicine, dentistry and engineering via an online system. The survey data conducted between February 14, 2022 and April 1, 2022 was recorded and analyzed in the SPSS 25 statistical package program.Results: A total of 233 students participated in the survey, 76 from the faculty of engineering, 121 from the faculty of medicine, and 36 from the faculty of dentistry. 159 of the students are women and 73 are men. The average age was found to be 22.8 +/- 1.9 years. Between the students of the faculty of engineering and the group studying in the field of health; There was a significant difference in knowing the HIV/AIDS difference, ways of protection and disease agent (p< 0.05). In addition, questions about the ways of HIV transmission; There is a significant difference between the two groups regarding genetic transmission, use of the same forks and knives, towels, public toilets, kissing, sneezing, shaking hands, and contamination from swimming pools (p< 0.05). Knowledge that it can be transmitted through blood transfusion, using the same razor and needle, getting a tattoo, pregnancy and birth was found to be significantly lower in the faculty of engineering (p< 0.05). Additionally, 14.5% of the faculty of engineering students thought that they could be protected from HIV/AIDS by exercising regularly and 36.8% thought that they were vaccinated against HIV/AIDS (p< 0.05).To the question of whether HIV/AIDS patients pose a threat to society, 33.5% of students studying in the field of health and 34.2% of students of the faculty of engineering answered yes. The rate of those who want to learn more about HIV/AIDS is 86% in the field of health and 80.3% in the faculty of engineering.Conclusion: In our study, it was also observed that although university students had a certain level of knowledge about HIV/AIDS, they had incomplete and wrong attitudes and behaviors. Necessary training on infectious diseases of public concern must cover all departments.Item The Prevalence, Etiologic Agents and Risk Factors for Urinary Tract Infection Among Spinal Cord Injury Patients(2014) Togan, Turhan; Azap, Ozlem Kurt; Durukan, Elif; Arslan, HandeBackground: Urinary tract infections (UTIs) are important causes of morbidity and mortality in patients with spinal cord injury and 22% of patients with acute spinal cord injury develop UTI during the first 50 days. Objectives: The aim of this study was to determine the prevalence, etiologic agents and risk factors for asymptomatic bacteriuria and symptomatic urinary tract infections in patients with spinal cord injury. Patients and Methods: This was a prospective investigation of spinal cord injury patients with asymptomatic bacteriuria and symptomatic urinary tract infections in Baskent University Medical Faculty Ayas Rehabilitation Center and Ankara Physical Therapy and Rehabilitation Center between January 2008 and December 2010. The demographic status, clinical and laboratory findings of 93 patients with spinal cord injury were analyzed in order to determine the risk factors for asymptomatic or symptomatic bacteriuria Results: Sixty three (67.7%) of 93 patients had asymptomatic bacteriuria and 21 (22.6%) had symptomatic urinary tract infection. Assessment of the frequency of urinary bladder emptying methods revealed that 57 (61.3%) of 93 patients employed permanent catheters and 24 (25.8%) employed clean intermittent catheterization. One hundred and thirty-five (48.0%) of 281 strains isolated form asymptomatic bacteriuria attacks and 16 (66.6%) of 24 strains isolated from symptomatic urinary tract infection attacks, totaling 151 strains, had multidrug resistance (P > 0.05). One hundred (70.4%) of 142 Escherichia coli strains and 19 (34.5%) of 55 Klebsiella spp strains proliferated in patients with asymptomatic bacteriuria; 8 (80%) of 10 E. coli strains and 4 (80%) of 5 Klebsiella spp. strains were multidrug resistant. Conclusions: The most common infectious episode among spinal cord injury patients was found to be urinary tract infection. E. coli was the most common microorganism isolated from urine samples. Antibiotic use in the previous 2 weeks or 3 months, hospitalization during the last one-year and previous diagnosis of urinary tract infection were the risk factors identified for the development of infections with multi-drug resistant isolates. Urinary catheterization was found to be the only independent risk factor contributing to symptomatic urinary tract infection.Item Emerging Escherichia coli O25b/ST131 Clone Predicts Treatment Failure in Urinary Tract Infections(2015) Can, Fusun; Azap, Ozlem Kurt; Seref, Ceren; Ispir, Pelin; Arslan, Hande; Ergonul, Onder; 25378460Background. We described the clinical predictive role of emerging Escherichia coli O25b/sequence type 131 (ST131) in treatment failure of urinary tract infection. Methods. In this prospective observational cohort study, the outpatients with acute cystitis with isolation of E. coli in their urine cultures were assessed. All the patients were followed up for clinical cure after 10 days of treatment. Detection of the E. coli O25:H4/ST131 clone was performed by multiplex polymerase chain reaction (PCR) for phylogroup typing and using PCR with primers for O25b rfb and allele 3 of the pabB gene. Results. In a cohort of patients with diagnosis of acute urinary cystitis, 294 patients whose urine cultures were positive with a growth of >10(4) colony-forming units/mL of E. coli were included in the study. In empiric therapy, ciprofloxacin was the first choice of drug (27%), followed by phosphomycin (23%), trimethoprim-sulfamethoxazole (TMP-SMX) (9%), and cefuroxime (7%). The resistance rate was 39% against ciprofloxacin, 44% against TMP-SMX, and 25% against cefuroxime. Thirty-five of 294 (12%) isolates were typed under the O25/ST131 clone. The clinical cure rate was 85% after the treatment. In multivariate analysis, detection of the O25/ST131 clone (odds ratio [ OR], 4; 95% confidence interval [ CI], 1.51-10.93; P = .005) and diabetes mellitus (OR, 2.1; 95% CI,.99-4.79; P = .05) were found to be significant risk factors for the treatment failure. In another multivariate analysis performed among quinolone-resistant isolates, treatment failure was 3 times more common among the patients who were infected with ST131 E. coli (OR, 3; 95% CI, 1.27-7.4; P = .012). Conclusions. In urinary tract infections, the E. coli ST131 clone seems to be a consistent predictor of treatment failure.