Tıp Fakültesi / Faculty of Medicine
Permanent URI for this collectionhttps://hdl.handle.net/11727/1403
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Item Comparison of Brain MRI Angiography and Brain MRI Cisternography in Patients with Hemifacial Spasm(2016) Ocal, Ruhsen; Tunc, Tuba; Ayas, Zeynep Ozozen; Yilmaz, Omer; Inan, Levent Ertugrul; 26908032The aim of this study was to compare the ability of brain magnetic resonance imaging angiography and brain magnetic resonance imaging cisternography of showing the neurovascular contiguity of the facial nerve in patients with hemifacial spasm. This study included a total of 35 patients (28 females, 7 males), with an average age of 57.5 +/- 13.8 years, who presented to our outpatient clinic of movement disorders. All patients were prospectively applied brain magnetic resonance imaging angiography and brain magnetic resonance imaging cisternography, and the results were evaluated by a radiologist who was blind to study protocol. The study included 35 patients, of whom 28 (80 %) were female and 7 (20 %) were male. Brain magnetic resonance imaging angiography demonstrated facial nerve compression of vascular origin in 5 (14.3 %) patients presenting with the clinical presentation of hemifacial spasm. Neurovascular compression of facial nerve was shown by brain magnetic resonance imaging cisternography in 13 (37.1 %) patients. No statistically significant difference was found between brain magnetic resonance imaging angiography and brain magnetic resonance imaging cisternography techniques in detecting a compressive interaction causing hemifacial spasm between facial nerve and adjacent vascular structures (p > 0.05).Item Posterior Reversible Encephalopathy Syndrome as an Initial Manifestation of Systemic Lupus Erythematosus(2017) Ayas, Zeynep Ozozen; Ocal, Ruhsen Once; Gundogdu, Asli Aksoy; 29870651; V-3553-2017; C-3992-2016Posterior reversible encephalopathy syndrome (PRES) is a disorder which is diagnosed with its characteristic clinical and radiological findings, typically resolves with treatment. The prevalence of PRES in systemic lupus erythematosus (SLE) patients is not exactly known. A systemic disorder frequently appears as a presenting symptom in SLE. However, in rare cases, the disease starts with a neurological manifestation. Here we report a 35-year-old woman presenting with a headache and blurred vision. She had neurologic symptoms and cerebral lesions on magnetic resonance imaging (MRI) suggesting PRES. The patient was diagnosed with SLE during the etiological investigation of PRES. In this article, we aimed to emphasize that PRES as an initial presentation of SLE.Item Alteratıon of Mean Platelet Volume in The Pathogenesıs of Acute Ischemıc Stroke: Cause or Consequence?(2018) Ayas, Zeynep Ozozen; Can, Ufuk; https://orcid.org/0000-0001-8689-417X; 29465900; AAJ-2999-2021Introduction - Platelets have a crucial role on vascular disease which are involved in pathogenesis of ischemic stroke. Platelet size is measured as mean platelet volume (MPV) and is a marker of platelet activity. Platelets contain more dense granules as the size increases and produce more serotonin and tromboglobulin (p-TO) than small platelets. In this study, the alteration of MPV values were investigated in patients with acute stroke, who had MPV values before stroke, during acute ischemic stroke and 7 days after the stroke. The relationship between this alteration and risk factors, etiology and localization of ischemic stroke were also investigated. Methods - Sixty-seven patients with clinically and radiologically established diagnoses of ischemic stroke were enrolled into the study and stroke etiology was classified by modified Trial of Org 10 172 in Acute Stroke Treatment (TOAST) classification and, modified Bamford classification was used for localization and stroke risk factors were also evaluated. The platelet counts and MPV values from patient files in patients who had values before stroke (at examination for another diseases), within 24 hours of symptom onset and after 7 further days were analysed. Results - MPV values increased after stroke (10.59 +/- 2.26) compared with acute stroke values (9.84 +/- 1.64) and the values before stroke (9.59 +/- 1.72) (p<0.0001); this alteration of MPV values occured 7 days after stroke (p<0.016). There was a positive correlation between age and MPV values during acute stroke (r=0.270; p<0.05). Patients with atrial fibrillation had higher alteration in the time of MPV compared with patients without atrial fibrillation (p>0.006). We assessed for gender, men (n=38) had a higher alteration in the time of MPV compared with women (n=29) (p=0.013). Conclusion - Although there was no alteration of platelet counts, MPV values were increased 7 days after stroke in patients with acute ischemic stroke.