Tıp Fakültesi / Faculty of Medicine

Permanent URI for this collectionhttps://hdl.handle.net/11727/1403

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2015 - 20173

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Author: search.filters.author.Arat, Yonca OzkanHas files: No

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    An Atypical Case of Microphthalmos With Cyst: Cyst Masquerading as Phthisical Eye
    (2015) Ozturker, Can; Kaynak, Pelin; Arat, Yonca Ozkan; Karabulut, Gamze Ozturk; Akar, Serpil; Demirok, Ahmet; 0000-0002-6578-7444; 24833453; AAA-2259-2021
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    Association of Disease Activity with Serum and Tear IL-2 Levels in Behc, et Disease
    (2016) Turkcuoglu, Peykan; Arat, Yonca Ozkan; Kan, Emrah; Kan, Elif Kilic; Chaudhry, Imtiaz A.; Koca, Suleyman; Celiker, Ulku; Ilhan, Nevin; https://orcid.org/0000-0002-6578-7444; 26110544; AAA-2259-2021
    Purpose: To investigate the association of Behcet disease activity with serum and tear interleukin-2 levels. Methods: The study was designed as a prospective case control study. The study population consisted of 45 patients with Behcet disease and 24 age and sex-matched healthy participants. Behcet disease patients were classified as active (24 patients) or inactive (21 patients) according to disease activity. Serum and tear interleukin-2 levels were determined using the enzyme-linked immunosorbent assay method. Results: The mean serum and tear interleukin-2 levels of the active disease, inactive disease, and control groups were 17.04 +/- 5.02 and 32.61 +/- 16.53 pg/mL; 15.20 +/- 4.68 and 29.61 +/- 8.30 pg/mL; and 14.22 +/- 4.18 and 28.89 +/- 8.73 pg/mL, respectively. There was no statistically significant difference between the groups with respect to all measured data. Conclusions: There was no significant difference in serum or tear IL-2 levels between Behcet patients and controls; there was no association of disease activity with serum and tear IL-2 levels.
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    Metastatic Embryonal Conjunctival Rhabdomyosarcoma in a 4-Year-Old Boy
    (2017) Sezenoz, Almila Sarigul; Karalezli, Aylin; Arat, Yonca Ozkan; Coban, Gokcen; Kiratli, Hayyam; Terzi, Aysen; 0000-0002-4010-2883; 0000-0002-7030-5454; 0000-0002-6578-7444; 26505233; P-7533-2014; AAJ-4860-2021
    The authors report the case of a 4-year-old boy who presented with unilateral ptosis and a mass lesion of palpebral conjunctiva of the left upper eyelid, that had been present for 2 weeks, and had rapidly enlarged. The lesion was salmon colored and was easily distinguished from the conjunctiva. There was no obvious orbital extension in the MRI studies. Excisional biopsy was performed through a conjunctival approach. The histopathology was consistent with embryonal rhabdomyosarcoma. Thoracoabdominal CT scans revealed nodules in both lungs, indicating stage 4 disease. The patient received chemotheraphy and intensity-modulated radiation therapy. Rhabdomyosarcoma confined to the conjunctiva and distant metastasis without orbital involvement is rare. It should be included in the differential diagnosis of any atypical conjunctival mass lesions in children, and histopathology is necessary to establish proper treatment. As the case indicates, detailed systemic evaluation and careful systemic follow up of these patients are mandatory.