Tıp Fakültesi / Faculty of Medicine

Permanent URI for this collectionhttps://hdl.handle.net/11727/1403

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    Analysis of Choroidal Thickness in AP-ROP, Threshold Disease and ROP Without Laser Photocoagulation
    (2016) Gokgoz-Ozisik, G.; Akkoyun, Imren; Oto, S.; Bayar, S. A.; Tarcan, A.; Kayhan, Z.; Yilmaz, G.; https://orcid.org/0000-0001-9037-7394; https://orcid.org/0000-0002-2860-7424; https://orcid.org/0000-0003-0171-4200; https://orcid.org/0000-0001-5109-755X; https://orcid.org/0000-0003-0579-1115; 26142227; ABG-6096-2021; AAK-7713-2021; AAJ-4668-2021; AAJ-2406-2021; AAJ-4623-2021
    Background. Enhanced depth imaging (EDI) and spectral domain optical coherence tomography (SD-OCT) provide high-definition cross-sectional images of the choroid. Information on alterations in choroidal thickness (CT) after laser photocoagulation (LC) in aggressive posterior retinopathy of prematurity (APROP) and threshold disease (TD) is rare. Patients and methods. A total of 75 eyes were retrospectively analyzed in 4 groups. Groups 1 and 2 included patients with APROP and TD, respectively, who underwent LC. Group 3 included ROP children who did not undergo LC and group 4 included full-term children. Infants aged >= 4 < 7, who had examination of subfoveal (SF) CT with SD-EDI-OCT, visual acuity (VA), spherical equivalent (SE), anterior segment and fundus examination, axial lenght (AXL) were included. The results of SFCT, VA and SE at the age of >= 4 < 7 years, AXL, gestational age (GA), birth weight (BW) and age at examination were compared between the groups. Potential risk factors (GA, BW, SE, AXL and SFCT) influencing visual acuity were evaluated by using multivariate linear regression analysis. Results. The results of SFCT and AXL were not significantly different between groups 2 and 3 or between groups 3 and 4. There was a significant difference between the other groups for SFCT and AXL and VA was significantly different between all groups. The SE was not significantly different between groups 3 and 4 but there was a significant difference for SE, BW and GA between the groups. Age at examination was not significantly different between the groups. Multivariate linear regression analysis revealed SFCT for groups 1 and 2, GA for group 3 and GA, SFCT and AXL for group 4 as independent risk factors influencing visual acuity. Conclusion. The regression model used for groups 1-4 explains the variation of the dependent risk factor LogMar VA for groups 1-4 with 31.2 %, 43.5 %, 9.6 % and 69.4 %, respectively. These values expressed in percentage demonstrate that even more predictors may influence the dependent factor LogMar VA than evaluated in the study.
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    Choroidal Thickness after Scleral Buckling Surgery versus Pars Plana Vitrectomy in Macula-Off Rhegmatogenous Retinal Detachment
    (2014) Akkoyun, I.; https://orcid.org/0000-0002-2860-7424; 24901425; AAK-7713-2021
    Purpose: Enhanced depth imaging (EDI) optical coherence tomography (OCT) provides high-definition cross-sectional images of the choroid. Information on alterations in choroidal thickness (CT) after scleral buckling surgery (SBS) and pars plana vitretomy (PPV) are rare. Methods: The medical charts of 44 patients (44 eyes) who underwent SBS versus PPV for macula-off rhegmatogenous retinal detachment (RRD) were retrospectively analysed. Patients with a follow-up >= 6 months were included. Postoperative EDI-OCT images concerning CT were evaluated 1 week, 1 month and 6 months postoperatively in 2 groups: group 1: cerclage + cryopexy + subretinal fluid drainage (SRD) + SF6 or air (n = 28 eyes), group 2: PPV + laser photocoagulation + C3F8. Subfoveal CT was compared between the groups and with the non-operated fellow eye. Results: Subfoveal CT in groups 1 and 2 was thicker 1 week postoperatively. There were no significant differences between the groups 2 or when comparing the operated eye with the fellow eye 1 and 6 months postoperatively. Conclusion: There were no differences in sub-foveal CT 1 and 6 months after SBS between the eye with macula-off RRD and the fellow eye. Thicker CT 1 week postoperatively after SBS may most likely be induced by scleral buckle reduced blood flow and increased haemostasis in the choroidal circulation and by scleral and choroidal inflammation after cryopexy versus laser photocoagulation after SBS versus PPV.
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    The Optimum Dosage of Prilocaine in Periprostatic Nerve Block During Transrectal Ultrasound Guided Prostate Biopsy: A New Approach in Dose Calculation
    (2016) Gonulalan, Umut; Kosan, Murat; Kervancioglu, Enis; Cicek, Tufan; Ozturk, Bulent; Ozkardes, Hakan
    Objective: We aimed to calculate the optimum dose of prilocaine per one mL prostate volume in periprostatic nerve block (PPNB) during transrectal ultrasound (TRUS) guided prostate biopsy (PBx). Materials and Methods: We retrospectively evaluated the medical records of 83 patients from whom 12 cores TRUS guided PBx were obtained between years 2011 and 2013. Prostatic sizes were evaluated separately as Size 1 (anterior-posterior on the axial plane), Size 2 (transversal), and Size 3 (cranial-caudal on the sagittal plane) for all patients. The visual analog scores (VAS) of the patients during PBx, prostatic volumes, and prilocaine doses per one mL prostate were evaluated. The correlation between VAS of patients during PBx and prostatic volume, the prostatic sizes and prilocaine dosage per one mL prostate was analyzed using Cubic regression test. Results: It was found that VAS scores of patients were significantly positive correlated with prostatic volume, Size 1, 2 and 3 (p<0.05). However, there was a negative significant correlation between VAS and prilocaine dose per one mL prostate volume (r=-0.402, p<0.01). The dose of 0.1 mL prilocaine infiltration per one mL prostatic tissue in PPNB was the maximum dose that caused a mild and under annoying pain (VAS<2) in patients according to cubic regression formula. Conclusion: Prilocaine dosage, prostatic volume and prostatic sizes (especially anterior-posterior and cranial-caudal) significantly affect VAS scores during TRUS guided PBx. The pain in TRUS guided PBx should be controlled with an optimum dose of prilocaine as 0.1 mL per one mL of prostatic tissue.