Fen Bilimleri Enstitüsü / Science Institute
Permanent URI for this collectionhttps://hdl.handle.net/11727/1392
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Item Conservation Genetics of the European Fallow Deer: A Reply to Marchesini et al.(2021) Baker, Karis H.; Gray, Howard W. I.; Peksen, Cigdem Akin; Hoelzel, A. Rus; 0000-0001-5736-3062In this letter, we revisit a study we published in 2017, following comment in a paper by Marchesini et al. published in this volume. We provide some further analyses that help us to reinforce the original conclusions of our earlier paper, and to address the points raised by Marchesini et al. We conclude that the concerns raised in their review do not alter the inference we presented earlier, and we identify issues with analyses presented by Marchesini et al. that limit their utility. The key points of inference remain that this species in Europe shows remarkably low levels of diversity within populations and strong structure among populations which can be explained by a combination of natural and anthropogenic processes.Item Detection of Resistance to Pyrethroid And Neonicotinoid Insecticides in the Greenhouse Whitefly, Trialeurodes Vaporariorum (Westw.) (Hemiptera: Aleyrodidae)(2021) Erdogan, Cem; Velioglu, A. Sibel; Gurkan, M. Oktay; Denholm, Ian; Moores, Graham D.In Turkey as elsewhere, control of the greenhouse whitefly, Trialeurodes vaporariorum (Westw.) (Hemiptera: Aleyrodidae), relies extensively on the use of insecticides, which can promote the development of insecticide resistance. In this study, resistance to commonly used pyrethroid and neonicotinoid insecticides was investigated using bioassays and biochemical analyses. Full dose-response bioassays using 11 samples of T. vaporariorum from three locations in Turkey disclosed resistance up to 8.1-fold, 16-fold and 11.4-fold for the neonicotinoids acetamiprid, imidacloprid and thiamethoxam, respectively. Corresponding figures for pyrethroids were 56.5-fold for cypermethrin and 116.4-fold for deltamethrin. All samples were characterized using polyacrylamide gel electrophoresis (PAGE) and by measuring non-specific esterase and glutathione-S-transferase (GST) activity. There is no positive relationship between esterase activity and resistance pyrethroid or neonicotinoid resistance. It is thought that esterase enzyme activity seen in T. vaporariorum may be at lest partially related to the resistance to insecticides, but it cannot be responsible as a single mechanism. No relationship has been determined between GST activity and resistance to pyrethroids or neonicotinoids. The practical implications of these results for control of whiteflies are discussed.Item Effects of Repair Techniques and Scarf Angles on Mechanical Performance of Composite Materials(2023) Karaduman, Beyza Naz; Elaldi, Faruk; https://orcid.org/0000-0003-0592-6868; AAG-5060-2019Today, composite materials, which have the advantage of strength and lightness ratio, have gained great importance especially in the aeronautical industry and automotive sector. With widespread use of composites, the repair of damages caused by external factors has also become an important research topic. In this study, the effects of different repair methods and scarf angles on the mechanical performance of the material were investigated. Scarf angles of 20 degrees, 30 degrees, and 45 degrees have been selected in order not to create too many scarf areas and to find a quick repair method. Also, a comparison of single scarf and double scarf repair was made to find a more robust solution. The samples were produced from carbon fiber prepreg and with the [45/0/90/0/45](2s) fiber orientation. Tensile, compression, and flexural (3-point bending) tests according to ASTM standards were applied to composite samples prepared with single scarf and double scarf repair configurations at different angles. The stress-strain curves obtained as a result of the tests showed that the specimens repaired at 20 degrees had the highest strength. In addition, it has been determined that the samples repaired with double scarf withstand higher forces compared to the samples repaired with single scarf at the same angle.Item An Overview of Deep Learning Algorithms and Their Applications in Neuropsychiatry(2021) Guney, Gokhan; Yigin, Busra Ozgode; Guven, Necdet; Colak, Burcin; Alici, Yasemin Hosgoren; Erzin, Gamze; Saygili, Gorkem; 0000-0003-3384-8131; 33888650Deep learning (DL) algorithms have achieved important successes in data analysis tasks, thanks to their capability of revealing complex patterns in data. With the advance of new sensors, data storage, and processing hardware, DL algorithms start dominating various fields including neuropsychiatry. There are many types of DL algorithms for different data types from survey data to functional magnetic resonance imaging scans. Because of limitations in diagnosing, estimating prognosis and treatment response of neuropsychiatric disorders; DL algorithms are becoming promising approaches. In this review, we aim to summarize the most common DL algorithms and their applications in neuropsychiatry and also provide an overview to guide the researchers in choosing the proper DL architecture for their research.Item A Polydentate Ligand Based On 2,2 '-Dipyridylamine Unit Linked Benzo-15-Crown-5; Alkali And Transition Metal Complexes; Photoresponsive Ligand; Antimicrobial Evaluation Against Pathogenic Microorganisms(2021) Kocoglu, Serhat; Hayvali, Zeliha; Ogutcu, Hatice; 0000-0002-3590-9084; GMW-9869-2022New double-armed benzo-15-crown-5 compound (L) was successfully synthesized from 4',5'-bis(bromethyl)benzo-15-crown-5 with 2,2'-dipyridylamine. The synthesized host molecule (L), the dipyridylamine unit was able to coordinate Ni2+, Cu2+ and Ag+ metal cations, whereas the crown ether moiety bound with the alkali metal cations (Na+ and K+). The structures of the ligand (L), alkali metal complexes (NaL and KL2) and transition metal complexes ([NiLOAc], [CuLOAc] and [AgLNO3]) were characterized by spectroscopic methods. NMR and mass data provided exact evidence of complex formation through both coordination centers of the new ligand (L). Both parts (dipyridyl and crown ether) were linked to form a potential fluorescent-sensing compound (L) for metal cations. Therefore, to investigate the metal selectivity, different metal cations (Na+, Mg2+, K+, Ba2+, Cr3+, Fe3+, Co2+, Ni2+, Cu2+, Zn2+ and Ag+) and the new sensing compound (L) fluorescence spectra were recorded. Coordinations with Zn2+, Fe3+ and Cu2+ induced obvious changes on their increasing concentrations in fluorescence spectra. Crown ethers, as representatives of supramolecular compounds, are also promising antibacterial active compounds because of their ionophoric features. Synthesized ligand (L) and complexes (NaL, KL2, [NiLOAc], [CuLOAc] and [AgLNO3]) also proved to be adjuvants that helped to overcome antimicrobial resistance in a range of bacteria and yeast. The antimicrobial activity of compounds was screened in vitro against some pathogenic Gram-positive bacteria, some Gram-negative bacteria and yeast.