Effects of Combined Visible and Infrared Light Rhinophototherapy in Patients With Allergic Rhinitis

dc.contributor.authorKoycu, Alper
dc.contributor.authorBas, Ceren
dc.contributor.authorMusabak, Ugur H.
dc.contributor.authorErbek, Selim Sermed
dc.contributor.authorKoca, Huseyin Samet
dc.contributor.authorBabakurban, Seda Turkoglu
dc.contributor.authorBahcecitapar, Melike
dc.contributor.orcIDhttps://orcid.org/0000-0003-1290-3509en_US
dc.contributor.pubmedID36266929en_US
dc.contributor.researcherIDAAF-3650-2021en_US
dc.date.accessioned2022-11-03T07:54:02Z
dc.date.available2022-11-03T07:54:02Z
dc.date.issued2023
dc.description.abstractBackground Intranasal phototherapy offers an alternative treatment method for patients with allergic rhinitis who cannot benefit from intranasal corticosteroids and oral antihistamines. Different wavelengths have been tried with promising results. Objective In this present study, we aimed to investigate the effects of visible light-infrared light phototherapy on clinical improvements together with its cytologic effects in patients with allergic rhinitis. Methods Patients with confirmed allergic rhinitis were given a 4-week course of intranasal phototherapy treatment. Weekly symptom questionnaires were applied to monitor clinical effects. Nasal lavage specimens were obtained before the start and at the completion of the 4-week therapy. Fluorescence-activated cell sorting analyses of CD16(+), CD24(+), and CD 45(+) cells were performed. Statistical analyses are performed of weekly changes in symptoms and cell counts. Results CD45(+)CD16(high)CD24(+) neutrophil count in nasal lavages decreased significantly whereas CD45(+)CD16(dim/-)CD24(+) eosinophil counts significantly increased and CD45(+) granulocyte counts remained unchanged. Symptom scores including nasal itching, nasal discharge, nasal obstruction, sneezing, eye itching, throat itching, and ear itching all statistically decreased compared to baseline at the end of 4 weeks. Conclusion Four-week course of intranasal phototherapy with visible and infrared light leads to clinical improvement in allergic rhinitis patients.en_US
dc.identifier.endpage73
dc.identifier.issn1945-8924en_US
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85140577561en_US
dc.identifier.startpage65
dc.identifier.urihttp://hdl.handle.net/11727/7970
dc.identifier.volume37
dc.identifier.wos000871135400001en_US
dc.language.isoengen_US
dc.relation.isversionof10.1177/19458924221133898en_US
dc.relation.journalAMERICAN JOURNAL OF RHINOLOGY & ALLERGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectallergic rhinitisen_US
dc.subjectphototherapyen_US
dc.subjectinfrareden_US
dc.subjectvisibleen_US
dc.subjectlighten_US
dc.subjectallergyen_US
dc.subjectrelieveren_US
dc.subjectdeviceen_US
dc.subjectintranasalen_US
dc.subjectflowcytometryen_US
dc.subjectreden_US
dc.titleEffects of Combined Visible and Infrared Light Rhinophototherapy in Patients With Allergic Rhinitisen_US
dc.typearticleen_US

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