Evaluation of Restless Legs Syndrome in Fibromyalgia Syndrome: An Analysis of Quality of Sleep and Life

Abstract

BACKGROUND AND OBJECTIVE: The aim of this study is to find prevalence and severity of restless legs syndrome (RLS) in patients with fibromyalgia syndrome (FMS) and detect effect of FMS and RLS coexistance on quality of sleep and life.

METHODS: In this study, presence and severity of RLS were detected in patients with FMS and Pitsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS) and Fibromyalgia Impact Questionnaire (FIQ) scores of all patients were measured.

RESULTS: One hundred and fifteen female patients with median age 49 (39.0-57.0) [median (25-75% interquartile range)] were included in the study. In 42.6% of patients RLS coexisting with FMS was found. RLS was classified as moderate in 42.9% of patients and as severe in 49.0% of patients. In patients with FMS ans RLS sleep quality, daytime sleepiness and quality of life were more severely impaired (PSQI scores were 9.0 +/- 4.4 vs 7.8 +/- 4.3, p = 0.003; ESS scores were 5.0(3.0-7.5) vs 3.0(1.0-4.3), p = 0.036 and FIQ scores were 68.1 +/- 9.8 vs 59.4 +/- 16.9, p = 0.027) compared to patients with only FMS. Prevalence of RLS was found higher in FMS than normal population and quality of sleep and quality of life were worse in patients with RLS.

CONCLUSIONS: Presence of RLS should be investigated in every patient with FMS and treatment plans should also cover RLS in case of coexistance with FMS. Prospective cohort studies are needed for better explanation of FMS and RLS coexistance.