Relationship between chest computed tomography findings and clinical conditions of coronavirus disease (COVID-19): A multicentre experience

dc.contributor.authorYilmaz Demirci, Nilgun
dc.contributor.authorUgras Dikmen, Asiye
dc.contributor.authorTasci, Canturk
dc.contributor.authorDogan, Deniz
dc.contributor.authorArslan, Yakup
dc.contributor.authorOcal, Nesrin
dc.contributor.authorTasar, Mustafa
dc.contributor.authorBozlar, Ugur
dc.contributor.authorArtuk, Cumhur
dc.contributor.authorYilmaz, Gulden
dc.contributor.authorKaracaer, Zehra
dc.contributor.authorAvci, Ismail Yasar
dc.contributor.authorTuncer Ertem, Gunay
dc.contributor.authorErdinc, Fatma Sebnem
dc.contributor.authorKinikli, Sami
dc.contributor.authorAltun Demircan, Serife
dc.contributor.authorErgun, Elif
dc.contributor.authorNercis Kosar, Pinar
dc.contributor.authorKarakoc, Ayse Esra
dc.contributor.authorGokcek, Atila
dc.contributor.authorAloglu, Melike
dc.contributor.authorGulgosteren, Sevtap
dc.contributor.authorAtikcan, Sukran
dc.contributor.authorAkcay, Sule
dc.contributor.authorErol, Cigdem
dc.contributor.authorHekimoglu, Koray
dc.contributor.authorCerit, Mahi Nur
dc.contributor.authorErbas, Gonca
dc.contributor.authorOzger, Hasan Selcuk
dc.contributor.authorBozdayi, Gulendam
dc.contributor.authorSenol, Esin
dc.contributor.authorYurdakul, Ahmet Selim
dc.contributor.authorYilmaz, Aydin
dc.contributor.orcID0000-0002-2535-2534en_US
dc.contributor.orcID0000-0002-0805-0841en_US
dc.contributor.pubmedID34105857en_US
dc.contributor.researcherIDAAJ-1219-2021en_US
dc.contributor.researcherIDAAD-9097-2021en_US
dc.date.accessioned2022-09-06T13:22:50Z
dc.date.available2022-09-06T13:22:50Z
dc.date.issued2021
dc.description.abstractAims This study aimed to investigate the clinical and chest computed tomography (CT) features associated with clinical parameters for coronavirus disease (COVID-19) in the capital of Turkey, Ankara. Materials and methods Epidemiological, clinical features, laboratory findings and radiological characteristics of 1563 hospitalised patients with COVID-19 in Ankara were collected, reviewed and analysed in this study. The risk factors associated with disease severity were investigated. Results Non-severe (1214; 77.7%) and severe cases (349; 22.3%) were enrolled in the study. Compared with the non-severe group, the severe group were significantly older and had more comorbidities (ie, hypertension, diabetes mellitus, cardiovascular disease and chronic kidney disease). Smoking was more common in the severe group. Severe patients had higher respiratory rates and higher incidences of cough and dyspnoea compared with non-severe patients. Compared with the non-severe patients, the severe patients had increased C-reactive protein (CRP), procalcitonin, neutrophil to lymphocyte ratio (NLR) and CRP/albumin ratio and decreased albumin. The occurrence rates of consolidation, subpleural sparing, crazy-paving pattern, cavity, halo sign, reversed halo sign, air bronchogram, pleural thickening, micronodule, subpleural curvilinear line and multilobar and bilateral involvement in the CT finding of the severe patients were significantly higher than those of the non-severe patients. Conclusions Many factors are related to the severity of COVID-19, which can help clinicians judge the severity of the patient and evaluate the prognosis. This cohort study revealed that male sex, age (>= 55 years), patients with any comorbidities, especially those with cardiovascular disease, dyspnoea, increased CRP, D-dimer and NLR, and decreased lymphocyte count and CT findings of consolidation and multilobar involvement were predictors of severe COVID-19.en_US
dc.identifier.issn1368-5031en_US
dc.identifier.issue9en_US
dc.identifier.scopus2-s2.0-85108252148en_US
dc.identifier.urihttp://hdl.handle.net/11727/7549
dc.identifier.volume75en_US
dc.identifier.wos000664762200001en_US
dc.language.isoengen_US
dc.relation.isversionof10.1111/ijcp.14459en_US
dc.relation.journalINTERNATIONAL JOURNAL OF CLINICAL PRACTICEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPREVALENCEen_US
dc.subjectPREDICTORen_US
dc.subjectMORTALITYen_US
dc.subjectTYPE-1en_US
dc.subjectRATIOen_US
dc.subjectCTen_US
dc.titleRelationship between chest computed tomography findings and clinical conditions of coronavirus disease (COVID-19): A multicentre experienceen_US
dc.typearticleen_US

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