Can a 1-day clear liquid diet with a split - dose polyethylene glycol overcome conventional practice patterns during the preparation for screening colonoscopy?

dc.contributor.authorEtik, Digdem Ozer
dc.contributor.authorSuna, Nuretdin
dc.contributor.authorGunduz, Cemre
dc.contributor.authorBostan, Ahmet
dc.contributor.authorOzdemir, Alperen
dc.contributor.authorGurel, Bade Yagmur
dc.contributor.authorYenisekerci, Ezgi
dc.contributor.authorBoyacioglu, Ahmet Sedat
dc.contributor.pubmedID31258137en_US
dc.date.accessioned2020-12-14T12:31:55Z
dc.date.available2020-12-14T12:31:55Z
dc.date.issued2019
dc.description.abstractBackground/Aims: A successful screening colonoscopy is closely linked to the quality of a bowel preparation. In this study, we aimed to determine the impact of a 1-day clear liquid diet (CLD) compared to a 3-day combined diet (CMD) accompanied by a split-dose regimen of polyethylene glycol and electrolyte lavage solution (PEG-ELS) for screening colonoscopy. Materials and Methods: This was a prospective, randomized, endoscopist-blinded study. Patients referred for screening colonoscopy were randomized to four groups as a 1-day CLD+PEG-ELS vs. a 1-day CLD+sulfate free (SF)-PEG-ELS and a 3-day CMD+PEG-ELS vs. a 3-day CMD+SF-PEG-ELS. An assessment of the quality of colon cleaning, tolerability to the preparation, and symptoms related to the preparation were recorded. Results: A total of 506 patients were enrolled in this study. The quality of bowel preparation was significantly inferior in the CMD+PEG-ELS group than CLD+PEG-ELS (p=0.004) and CMD+SF-PEG-ELS groups (p=0.007). There were no statistical differences among the groups in terms of the polyp detection rate. With respect to an easy rating of diet following and the consumption of laxative, there were no significant differences among the four groups. Gastric fullness and nausea/vomiting were pointed out much more, especially in the SF-PEG-ELS users (p=0.008 and p=0.004, respectively). Conclusion: A 1-day CLD was not inferior to a 3-day CMD for colonoscopy preparation in terms of bowel cleaning, the polyp detection rate, and patient tolerance.en_US
dc.identifier.endpage825en_US
dc.identifier.issn1300-4948en_US
dc.identifier.issue9en_US
dc.identifier.startpage817en_US
dc.identifier.urihttp://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6750826&blobtype=pdf
dc.identifier.urihttp://hdl.handle.net/11727/5031
dc.identifier.volume30en_US
dc.identifier.wos000486650500008en_US
dc.language.isoengen_US
dc.relation.isversionof10.5152/tjg.2019.19071en_US
dc.relation.journalTURKISH JOURNAL OF GASTROENTEROLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBowel cleaningen_US
dc.subjectclear liquid dieten_US
dc.subjectlow-residue dieten_US
dc.subjectscreening for colon canceren_US
dc.titleCan a 1-day clear liquid diet with a split - dose polyethylene glycol overcome conventional practice patterns during the preparation for screening colonoscopy?en_US
dc.typearticleen_US

Files

Original bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
tjg-30-9-817.pdf
Size:
157.47 KB
Format:
Adobe Portable Document Format
Description:

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description: