Dermatoscopy Of Nodular/Plaque-Type Primary Cutaneous T- And B-Cell Lymphomas: A Retrospective Comparative Study With Pseudolymphomas And Tumoral/Inflammatory Mimickers By The International Dermoscopy Society

dc.contributor.authorErrichetti, Enzo
dc.contributor.authorGeller, Shamir
dc.contributor.authorZalaudek, Iris
dc.contributor.authorLongo, Caterina
dc.contributor.authorKyrgidis, Athanassios
dc.contributor.authorAkay, Bengu Nisa
dc.contributor.authorPiccolo, Vincenzo
dc.contributor.authorMyskowski, Patricia
dc.contributor.authorVitiello, Paola
dc.contributor.authorRusso, Teresa
dc.contributor.authorArgenziano, Giuseppe
dc.contributor.authorSlawinska, Martyna
dc.contributor.authorSokolowska-Wojdylo, Malgorzata
dc.contributor.authorSobjanek, Michal
dc.contributor.authorToncic, Ruzica Jurakic
dc.contributor.authorRados, Jaka
dc.contributor.authorDrvar, Daniela Ledic
dc.contributor.authorCeovic, Romana
dc.contributor.authorKaminska-Winciorek, Grazyna
dc.contributor.authorLanssens, Sven
dc.contributor.authorGulec, Ayse Tulin
dc.contributor.authorLobato-Berezo, Alejandro
dc.contributor.authorDamiani, Giovanni
dc.contributor.authorMaione, Vincenzo
dc.contributor.authorCalzavara-Pinton, Piergiacomo
dc.contributor.authorSotiriou, Elena
dc.contributor.authorStinco, Giuseppe
dc.contributor.authorApalla, Zoe
dc.contributor.authorLallas, Aimilios
dc.contributor.pubmedID34695527en_US
dc.date.accessioned2022-12-23T08:23:54Z
dc.date.available2022-12-23T08:23:54Z
dc.date.issued2022
dc.description.abstractBackground: Limited data on dermatoscopy of nodular/plaque-type T-/B-cell primary cutaneous lymphomas (PCLs) is available. Objective: To describe dermatoscopic features of nodular/plaque-type PCLs, comparing them with those of clinical mimickers (pseudolymphomas, tumors, and inflammatory lesions) and investigating possible differences according to histologic subtypes. Methods: Participants were invited to join this retrospective, multicenter case-control study by submitting histologically/immunohistochemically confirmed instances of nodular/plaque-type PCLs and controls. Standardized assessments of the dermatoscopic images and comparative analyses were performed. Results: A total of 261 lesions were included (121 PCLs and 140 controls). Orange structureless areas were the strongest PCL dermatoscopic predictor on multivariate analysis compared with tumors and non infiltrative inflammatory dermatoses. On the other hand, a positive association was found between PCLs and either unfocused linear vessels with branches or focal white structureless areas compared with infiltrative inflammatory dermatoses, whereas white lines were predictive of PCLs over pseudolymphomas. Differences in the vascular pattern were also seen between B-and T-cell PCLs and among B-cell PCL subtypes. Limitations: Retrospective design and the lack of a dermatoscopic-pathologic correlation analysis. Conclusion: Nodular/plaque-type PCLs display dermatoscopic clues, which may partially vary according to histologic subtype and whose diagnostic relevance depends on the considered clinical differential diagnoses. ( J Am Acad Dermatol 2022;86:774-81.)en_US
dc.identifier.endpage781en_US
dc.identifier.issn0190-9622en_US
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85118897038en_US
dc.identifier.startpage774en_US
dc.identifier.urihttp://hdl.handle.net/11727/8420
dc.identifier.volume86en_US
dc.identifier.wos000840267700011en_US
dc.language.isoengen_US
dc.relation.isversionof10.1016/j.jaad.2021.10.020en_US
dc.relation.journalJOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectdermatoscopyen_US
dc.subjectinfiltrative dermatosesen_US
dc.subjectinflammatory dermatosesen_US
dc.subjectlymphomasen_US
dc.subjectpseudolym-phomasen_US
dc.subjecttumorsen_US
dc.titleDermatoscopy Of Nodular/Plaque-Type Primary Cutaneous T- And B-Cell Lymphomas: A Retrospective Comparative Study With Pseudolymphomas And Tumoral/Inflammatory Mimickers By The International Dermoscopy Societyen_US
dc.typearticleen_US

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