Evaluation of the tear parameters of ovulation induction patients in a short time period with anterior segment optical coherence tomography

dc.contributor.authorColak, Eser
dc.contributor.authorUlusoy, Mahmut Oguz
dc.contributor.authorCeran, Mehmet Ufuk
dc.contributor.authorTasdemir, Umit
dc.contributor.authorKal, Ali
dc.contributor.authorOzcimen, Emel Ebru
dc.contributor.pubmedID33470279en_US
dc.date.accessioned2021-03-20T14:20:09Z
dc.date.available2021-03-20T14:20:09Z
dc.date.issued2020
dc.description.abstractPurpose: The effects of sex steroid hormones on tearparameters are known. Theaim of this studywas to examine the effects on tear parameters during exposure to high-dose sex steroids in a short period of time. Methods: Forty patients who were admitted to the infertility clinic of our hospital and planned to undergo ovulation induction with exogenous gonadotropins were included in our study. Prior tothe initiation of ovulation induction, the basal levels of estradiol were measured on day 3 of the menstrual cycle and ophthalmologic examinations were performed by the ophthalmology department of our hospital. The estradiol levels were-measured on the day ofovulation induction usinghuman chorionic gonadotropin and compared with basal estradiol; eye examinations were also repeated. Result: Forty women with reproductive period and average age of 33.3 +/- 4.2 years were included in this study. Basal levels of estradiol were significantly (p<0.001) higher after ovulation induction than before induction. The scores in the break-up timeand after induction were 6.2 +/- 2.8 sn and 8.4 +/- 1.4 sn, respectively. The values of Schirmer's test were 14.3 +/- 7.1 mm and 20.6 +/- 6.2 mm before and after induction, respectively. Both values were significantly higher after ovulation induction (p<0.001; p=0.001, respectively). Conclusion: We observed improvemet in tear function tests following the use of estradiol even for a limited time .The use of estradiol during menopause may improve dry eye symptoms in patients.en_US
dc.identifier.endpage516en_US
dc.identifier.issn0004-2749en_US
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85100230537en_US
dc.identifier.startpage511en_US
dc.identifier.urihttps://www.scielo.br/pdf/abo/v83n6/0004-2749-abo-83-06-0511.pdf
dc.identifier.urihttp://hdl.handle.net/11727/5594
dc.identifier.volume83en_US
dc.identifier.wos000608977600009en_US
dc.language.isoengen_US
dc.relation.isversionof10.5935/0004-2749.20200095en_US
dc.relation.journalARQUIVOS BRASILEIROS DE OFTALMOLOGIAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEstradiolen_US
dc.subjectDry eye syndromeen_US
dc.subjectFertile perioden_US
dc.subjectMenopauseen_US
dc.subjectTomographyen_US
dc.subjectoptical coherenceen_US
dc.titleEvaluation of the tear parameters of ovulation induction patients in a short time period with anterior segment optical coherence tomographyen_US
dc.typearticleen_US

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