Hypoxia parameters, physical variables, and severity of obstructive sleep apnea

dc.contributor.authorAvci, Suat
dc.contributor.authorAvci, Aynur Yilmaz
dc.contributor.authorLakadamyali, Huseyin
dc.contributor.authorAydin, Erdinc
dc.contributor.orcID0000-0001-9004-9382en_US
dc.contributor.orcID0000-0001-6864-7378en_US
dc.contributor.orcID0000-0003-2155-8014en_US
dc.contributor.researcherIDF-6770-2019en_US
dc.contributor.researcherIDAAJ-2379-2021en_US
dc.contributor.researcherIDO-3636-2018en_US
dc.date.accessioned2019-06-20T08:36:35Z
dc.date.available2019-06-20T08:36:35Z
dc.date.issued2016
dc.description.abstractObjective: To determine the relation between hypoxia and physical parameters in patients who had different levels of severity of obstructive sleep apnea (OSA). Methods: This was a retrospective, cross-sectional study of 259 men who were evaluated with overnight polysomnography. Severity of OSA was graded based on the apnea-hypopnea index (AHI): normal/simple snoring (n=31); mild OSA (n=70); moderate OSA (n=63); severe OSA (n=95). Patients with different severity were divided into subgroups, based on having the lowest or highest values of the total sleep time with oxygen saturation <90% (ST90) or minimum oxygen saturation (min SaO(2)). Results: Median AHI was 20.4 events/hour. Univariate analysis showed that ST90 was correlated with AHI (r=0.772; p <= 0.001) and Epworth sleepiness scale (ESS) (r=0.344; p <= 0.001), and min SaO(2) was inversely correlated with AHI (r=-0.748; p <= 0.001) and ESS (r=-0.319; p <= 0.001). Multivariate linear regression showed that ST90 was independently associated with AHI, ESS, and neck circumference, and min SaO(2) was independently inversely associated with AHI, ESS, and body mass index (BMI). In patients who had severe OSA, the subgroups which had lowest and highest min SaO(2) differed significantly in BMI, modified Mallampati score, neck and waist circumferences, and ret-roglossal Muller grade. In patients with percentage of sleep time with oxygen saturation below 90% (CT90) <10%, the upper limit of ST90 was 36 minutes and corresponded to 70% lower limit of min SaO(2). Conclusion: Hypoxia parameters show significant variation in OSA severity categories. None of the physical parameters had clinically useful relations with hypoxia parameters in OSA patients except patients who had severe OSA.en_US
dc.identifier.endpage63en_US
dc.identifier.issn2149-7109
dc.identifier.issue2en_US
dc.identifier.startpage55en_US
dc.identifier.urihttp://www.jmedupdates.org/Port_Doc/ENT_2016/ENT_2016002/ENT_2016002001.pdf
dc.identifier.urihttp://hdl.handle.net/11727/3619
dc.identifier.volume6en_US
dc.identifier.wos000390932600001en_US
dc.language.isoengen_US
dc.relation.isversionof10.2399/jmu.2016002003en_US
dc.relation.journalENT UPDATESen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectApnea-hypopnea indexen_US
dc.subjectOxygen saturationen_US
dc.subjectPhysical parametersen_US
dc.titleHypoxia parameters, physical variables, and severity of obstructive sleep apneaen_US
dc.typearticleen_US

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
ENT_2016002001.pdf
Size:
127.89 KB
Format:
Adobe Portable Document Format
Description:

License bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description: