Burkitt Lymphoma After Transplant: An Aggressive Lymphoproliferative Disease

dc.contributor.authorOzkan, Eylem Akar
dc.contributor.authorOzdemir, B. Handan
dc.contributor.authorAkdur, Aydincan
dc.contributor.authorDeniz, E. Ebru
dc.contributor.authorHaberal, Mehmet
dc.contributor.orcIDhttps://orcid.org/0000-0002-7528-3557en_US
dc.contributor.orcIDhttps://orcid.org/0000-0002-8726-3369en_US
dc.contributor.pubmedID24635811en_US
dc.contributor.researcherIDX-8540-2019en_US
dc.contributor.researcherIDAAA-3068-2021en_US
dc.date.accessioned2024-02-27T08:41:37Z
dc.date.available2024-02-27T08:41:37Z
dc.date.issued2014
dc.description.abstractPosttransplant lymphoproliferative disorder (Burkitt lymphoma) may occur after liver transplant. A 3.5-year-old boy who was 17 months after liver transplant developed multiple millimeter-sized nodular lesions in the liver. Before transplant, the patient tested seronegative for Epstein-Barr virus; within 1 month after transplant, he tested seropositive for Epstein-Barr virus (1000 copies). Biopsy of the liver nodules showed posttransplant lymphoproliferative disorder (Burkitt lymphoma). Tacrolimus was stopped, sirolimus was started, and the patient was treated with chemotherapy (etoposide, doxorubicin, cyclophosphamide, corticosteroids and intrathecal methotrexate). Remission was achieved, and follow-up at 76 months after transplant showed no recurrence of the posttransplant lymphoproliferative disorder. In conclusion, posttransplant lymphoproliferative disorder (Burkitt lymphoma) may occur after liver transplant, and monitoring Epstein-Barr virus level may helpful after transplant because of the association between Epstein-Barr virus and Burkitt lymphoma.en_US
dc.identifier.endpage138en_US
dc.identifier.issn1304-0855en_US
dc.identifier.scopus2-s2.0-84897463294en_US
dc.identifier.startpage136en_US
dc.identifier.urihttp://hdl.handle.net/11727/11648
dc.identifier.volume12en_US
dc.identifier.wos000335626600030en_US
dc.language.isoengen_US
dc.relation.isversionof10.6002/ect.25Liver.P28en_US
dc.relation.journalEXPERIMENTAL AND CLINICAL TRANSPLANTATIONen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCanceren_US
dc.subjectEpstein-Barr virusen_US
dc.subjectLiver transplanten_US
dc.subjectPediatricsen_US
dc.titleBurkitt Lymphoma After Transplant: An Aggressive Lymphoproliferative Diseaseen_US
dc.typearticleen_US

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