Clear Cell Acanthoma in an Unexpected Location

Abstract

Clear cell acanthoma (CCA) is an uncommon, benign, and slow progressing lesion originating from epidermal keratinocytes. Lesions are not gender specific and usually diagnosed at 50-60 years of age. It is generally represented in the lower extremities. CCA was first described by Degos et al. as "Degos acanthoma" for a lesion presented in the lower extremity. Clinically, it is hard to distinguish whether the lesion is benign or malignant. Final diagnosis can be made histopathologically. Biopsy material is periodic acid-Schiff positive. While CAA commonly presents itself in the lower extremities, our patient had a CAA in his abdominal region.