Acrokeratosis Verruciformis of Hopf Exhibiting Darier Disease-Like Cytological Features

dc.contributor.authorHarman, M.
dc.contributor.authorDurdu, M.
dc.contributor.orcIDhttps://orcid.org/0000-0003-1247-3932en_US
dc.contributor.pubmedID27663152en_US
dc.contributor.researcherIDH-9068-2019en_US
dc.date.accessioned2023-06-23T10:29:47Z
dc.date.available2023-06-23T10:29:47Z
dc.date.issued2016
dc.description.abstractThe relationship between acrokeratosis verruciformis (AVH; also known as Hopf disease) and Darier disease (DD) has been debated for several decades. There is still substantial controversy over the characterization and association of AVH with DD. Certain histopathological features overlapping with those of DD have been demonstrated in patients with AVH. Although cytological findings have been described in DD, no study has identified the cytological changes in AVH. We report a case of AVH exhibiting a DD-like cytological manifestation. The samples from the most prominent lesions were examined by split-skin smear test. Cytological examination showed acantholytic keratinocytes, dyskeratotic acantholytic cells, corps ronds and grains. Histopathological examination showed compact hyperkeratosis, hypergranulosis, slight acanthosis, circumscribed epidermal elevations resembling church spires, and a cleft in the granular layer with several acantholytic cells. Our case indicates that the cytological findings of AVH are similar to those of DD.en_US
dc.identifier.endpage763en_US
dc.identifier.issn0307-6938en_US
dc.identifier.issue7en_US
dc.identifier.scopus2-s2.0-84988464961en_US
dc.identifier.startpage761en_US
dc.identifier.urihttp://hdl.handle.net/11727/9824
dc.identifier.volume41en_US
dc.identifier.wos000384817100011en_US
dc.language.isoengen_US
dc.relation.isversionof10.1111/ced.12910en_US
dc.relation.journalCLINICAL AND EXPERIMENTAL DERMATOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMUTATIONen_US
dc.subjectATP2A2en_US
dc.titleAcrokeratosis Verruciformis of Hopf Exhibiting Darier Disease-Like Cytological Featuresen_US
dc.typearticleen_US

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