Evaluation of right ventricular function in operated tetralogy of Fallot patients with tissue Doppler imaging before and after pulmonary valve replacement

dc.contributor.authorVaran, Birgul
dc.contributor.authorGursu, Hazim Alper
dc.contributor.authorErdogan, Ilkay
dc.contributor.authorOzkan, Murat
dc.contributor.pubmedID32082764en_US
dc.date.accessioned2019-05-06T11:13:45Z
dc.date.available2019-05-06T11:13:45Z
dc.date.issued2018
dc.description.abstractBackground: This study aims to investigate the efficacy of tissue Doppler echocardiography for the diagnosis of right ventricular dysfunction and for the evaluation of the response to pulmonary valve replacement. Methods: Between December 2008 and December 2010, a total of 15 patients (8 males, 7 females; mean age: 14.5 +/- 4.5 years; range, 7 to 22 years) with pulmonary valve insufficiency in the follow-up of total correction of tetralogy of Fallot who underwent pulmonary valve replacement were included in the study. Echocardiographic imaging was performed before and one, three, and six months after replacement. Using pulse wave Doppler, early diastolic E and late diastolic A waves were measured in the flow velocity curve of tricuspid valve. Tissue Doppler measurements were made from the basal segment of right ventricular free wall and interventricular septum. S, e, and a myocardial velocities, isometric contraction time, isovolumetric relaxation time and ejection time were measured. Myocardial performance index was calculated for each patient. Results: In pre-pulmonary valve replacement phase, s, e, a velocities and ejection time were lower in the interventricular septum compared to the basal segment of right ventricular free wall, while isometric contraction time, isovolumetric relaxation time and myocardial performance index values were higher. In the first post-replacement month, there was a significant decrease in the s value of interventricular septum, compared to pre-pulmonary valve replacement period; isometric contraction time decreased and myocardial performance index increased in the first post-pulmonary valve replacement month in the free wall of right ventricle, while isovolumetric relaxation time decreased in the postoperative third month, and s velocity, isometric contraction time and myocardial performance index increased in the postoperative sixth month. Pre-pulmonary valve replacement tissue Doppler values at the septum showed that myocardial systolic and diastolic dysfunction developed earlier than the basal segment of right ventricular free wall. This result showed that right ventricular recovery was not complete in the sixth post-pulmonary valve replacement month. Conclusion: Tissue Doppler can show right ventricular dysfunction before replacement, but it may be insufficient to visualize right ventricular recovery until six months after treatment.en_US
dc.identifier.endpage364en_US
dc.identifier.issn1301-5680
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85050320387en_US
dc.identifier.startpage359en_US
dc.identifier.urihttp://tgkdc.dergisi.org/uploads/pdf/pdf_TGKDC_2687.pdf
dc.identifier.urihttp://hdl.handle.net/11727/3193
dc.identifier.volume26en_US
dc.identifier.wos000439420000003en_US
dc.language.isoengen_US
dc.relation.isversionof10.5606/tgkdc.dergisi.2018.14885en_US
dc.relation.journalTURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEchocardiographyen_US
dc.subjectPulmonary valve replacementen_US
dc.subjectSystolic dysfunctionen_US
dc.subjectTetralogy of Falloten_US
dc.titleEvaluation of right ventricular function in operated tetralogy of Fallot patients with tissue Doppler imaging before and after pulmonary valve replacementen_US
dc.typearticleen_US

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