Early Changes in Atrial Electromechanical Coupling in Patients with Hypertension: Assessment by Tissue Doppler Imaging

dc.contributor.authorAvci, Burcak Kilickiran
dc.contributor.authorGulmez, Oyku
dc.contributor.authorDonmez, Guclu
dc.contributor.authorPehlivanoglu, Seckin
dc.contributor.pubmedID27231168en_US
dc.date.accessioned2019-08-08T08:44:48Z
dc.date.available2019-08-08T08:44:48Z
dc.date.issued2016
dc.description.abstractBackground: Hypertension (HT) is associated with atrial electrophysiological abnormalities. Echocardiographic pulsed wave tissue Doppler imaging (TDI) is one of the noninvasive methods for evaluation of atrial electromechanical properties. The aims of our study were to investigate the early changes in atrial electromechanical conduction in patients with HT and to assess the parameters that affect atrial electromechanical conduction. Methods: Seventy-six patients with HT (41 males, mean age 52.6 +/- 9.0 years) and 41 controls (22 males, mean age 49.8 +/- 7.9 years) were included in the study. Atrial electromechanical coupling at the right (PRA), left (PLA), interatrial septum (PIS) were measured with TDI. Intra- (right: PIS-PRA, left: PLA-PIS) and inter-atrial (PLA-PRA) electromechanical delays were calculated. Maximum P-wave duration (Pmax) was calculated from 12-lead electrocardiogram. Results: Atrial electromechanical coupling at PLA (76.6 +/- 14.1 ms vs. 82.9 +/- 15.8 ms, P = 0.036), left intra-atrial (10.9 +/- 5.0 ms vs. 14.0 +/- 9.7 ms, P = 0.023), right intra-atrial (10.6 +/- 7.8 ms vs. 14.5 +/- 10.1 ms, P = 0.035), and interatrial electromechanical (21.4 +/- 9.8 ms vs. 28.3 +/- 12.7 ms, P = 0.003) delays were significantly longer in patients with HT. The linear regression analysis showed that left ventricular (LV) mass index and Pmax were significantly associated with PLA (P = 0.001 and P = 0.002, respectively), and the LV mass index was the only related factor for interatrial delay (P = 0.001). Conclusions: Intra- and interatrial electromechanical delay, PLA were significantly prolonged in hypertensive patients. LV mass index and Pmax were significantly associated with PLA, and the LV mass index was the only related factor for interatrial delay. The atrial TDI can be a valuable method to assess the early changes of atrial electromechanical conduction properties in those patients.en_US
dc.identifier.endpage1315en_US
dc.identifier.issn0366-6999
dc.identifier.issue11en_US
dc.identifier.scopus2-s2.0-84969677579en_US
dc.identifier.startpage1311en_US
dc.identifier.urihttps://insights.ovid.com/crossref?an=00029330-201606050-00009
dc.identifier.urihttp://hdl.handle.net/11727/3835
dc.identifier.volume129en_US
dc.identifier.wos000377519100009en_US
dc.language.isoengen_US
dc.relation.isversionof10.4103/0366-6999.182846en_US
dc.relation.journalCHINESE MEDICAL JOURNALen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAtrial Electromechanical Couplingen_US
dc.subjectHypertensionen_US
dc.subjectTissue Doppler Imagingen_US
dc.titleEarly Changes in Atrial Electromechanical Coupling in Patients with Hypertension: Assessment by Tissue Doppler Imagingen_US
dc.typearticleen_US

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