High Prolactin Level as a Predictor of Vasospasm in Aneurysmal Subarachnoidal Hemorrhage

dc.contributor.authorKircelli, Atilla
dc.contributor.authorCoven, Ilker
dc.contributor.authorDuman, Enes
dc.contributor.authorPinar, Huseyin Ulas
dc.contributor.authorBasaran, Betul
dc.contributor.orcID0000-0003-0473-6763en_US
dc.contributor.orcID0000-0003-2109-1274en_US
dc.contributor.pubmedID28784938en_US
dc.contributor.researcherIDQ-2420-2015en_US
dc.contributor.researcherIDAAK-5299-2021en_US
dc.date.accessioned2019-06-11T12:50:22Z
dc.date.available2019-06-11T12:50:22Z
dc.date.issued2017
dc.description.abstractBackground: Aneurysmal subarachnoid hemorrhage (aSAH) is a destructive syndrome with a mortality rate of 50%. Recent studies have also suggested a high pervasiveness of hypothalamic-pituitary insufficiency in up to 45% of patients after aSAH. Prolactin has been associated with the pathogenesis of hypertensive irregularities that are linked to pregnancy. Material/Methods: We identified a group of 141 patients with spontaneous SAH due to a ruptured cerebral aneurysm; these patients were operated on at our institution's Neurosurgery and Interventional Radiology Department between 2011 and June 2015. All of the data were obtained retrospectively from medical records. Results: The hormonal abnormalities observed in the initial 24 h after ictus in subjects with subarachnoid SAH were caused by stressful stimulation aggravated by intracranial bleeding. Conclusions: The elevated prolactin levels that occur in patients with aSAH can be used in conjunction with other auxiliary factors that we believe may be beneficial to vasospasm.en_US
dc.identifier.endpage3836en_US
dc.identifier.issn1643-3750
dc.identifier.scopus2-s2.0-85029493086en_US
dc.identifier.startpage3831en_US
dc.identifier.urihttp://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5560194&blobtype=pdf
dc.identifier.urihttp://hdl.handle.net/11727/3454
dc.identifier.volume23en_US
dc.identifier.wos000407016900001en_US
dc.language.isoengen_US
dc.relation.isversionof10.12659/MSM.906010en_US
dc.relation.journalMEDICAL SCIENCE MONITORen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectProlactinen_US
dc.subjectSubarachnoid Hemorrhageen_US
dc.subjectVasospasmen_US
dc.subjectIntracranialen_US
dc.titleHigh Prolactin Level as a Predictor of Vasospasm in Aneurysmal Subarachnoidal Hemorrhageen_US
dc.typearticleen_US

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