Tacrolimus-Induced Diabetic Ketoacidosis After Allogeneic Bone Marrow Transplant

Abstract

New-onset diabetes mellitus after solid-organ transplant makes for complicated tacrolimus immuno suppression. However, tacrolimus-associated diabetic ketoacidosis has not been reported in bone marrow transplant. We report 24-year-old women, hospitalized with diabetic ketoacidosis, 70 days after undergoing a bone marrow transplant with tacrolimus immunosuppression. Clinicians should be wary about tacrolimus levels and the risk of hyperglycemic states after bone marrow transplant as with other solid-organ transplants.