An Evaluation Of The Factors Affecting The Clinical And Laboratory Findings, Prognosis, And Treatment Response İn Children With Chronic Urticaria

dc.contributor.authorSancakli, Ozlem
dc.contributor.pubmedID34907626en_US
dc.date.accessioned2022-06-22T11:55:25Z
dc.date.available2022-06-22T11:55:25Z
dc.date.issued2021
dc.description.abstractChronic urticaria (CU) is a rare disease in childhood, and studies in children are limited. In this study, the aim was to investigate the clinical and laboratory findings and demographic characteristics of children with CU and to determine the factors affecting prognosis. The study included 141 patients aged 0-18 years who were diagnosed with CU in the pediatric allergy outpatient clinic between January 1, 2013, and December 31, 2018. Risk factors related to prognosis were investigated by comparing the duration of CU and treatment response with clinical and etiological features. IBM SPSS version 24 was used for statistical analyses. In the study group, the female/male ratio was 69/55, and the median age at first visit was 9.5 years (min:1, max:17). Among patients, 63 (44.5%) had an accompanying atopic disease, and 23 (16.3%) had chronic disease. Of the patients, 124 (88%) had chronic spontaneous urticaria, and 17 patients (12%) had chronic inducible urticaria (CIU). Of those with CIU, 72.2% had symptomatic dermographism, 16.7% had cholinergic urticaria, and 11.1% had cold urticaria. After the evaluations, the most common pathological findings in our patients were intestinal parasitosis (n = 14), anemia (n = 10), and urinary tract infection (n = 8). The median total duration of urticaria was 47 weeks (min:8, max:284). The duration of urticaria was longer in patients with atopy (p < 0.05), and the group that went into remission with standard-dose antihistamine was the group with highest eosinophil count (p = 0.022). In most children with CU, the underlying cause/disease cannot be determined. In our study, treatable triggers were found in some of the patients. Therefore, it is appropriate for each patient to be evaluated with selected laboratory tests after detailed history and physical examination.en_US
dc.identifier.endpage8en_US
dc.identifier.issn1396-0296en_US
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85121536842en_US
dc.identifier.startpage1en_US
dc.identifier.urihttp://hdl.handle.net/11727/7116
dc.identifier.volume35en_US
dc.identifier.wos000732473500001en_US
dc.language.isoengen_US
dc.relation.isversionof10.1111/dth.15261en_US
dc.relation.journalDERMATOLOGIC THERAPYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectchildrenen_US
dc.subjecttreatmenten_US
dc.subjecturticariaen_US
dc.titleAn Evaluation Of The Factors Affecting The Clinical And Laboratory Findings, Prognosis, And Treatment Response İn Children With Chronic Urticariaen_US
dc.typearticleen_US

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