Comparative effects of photobiomodulation therapy at wavelengths of 660 and 808 nm on regeneration of inferior alveolar nerve in rats following crush injury

dc.contributor.authorDiker, Nurettin
dc.contributor.authorAytac, Duygu
dc.contributor.authorHelvacioglu, Fatma
dc.contributor.authorOguz, Yener
dc.contributor.orcID0000-0002-6026-0045en_US
dc.contributor.pubmedID31273571en_US
dc.contributor.researcherIDAAH-8887-2021en_US
dc.date.accessioned2021-06-30T18:36:30Z
dc.date.available2021-06-30T18:36:30Z
dc.date.issued2020
dc.description.abstractThe aim of the present study was to investigate the therapeutic effects of 660-nm and 880-nm photobiomodulation therapy (PBMT) following inferior alveolar nerve (IAN) crush injury. Following the nerve crush injuries of IAN, 36 Wistar rats were randomly divided into three groups as follows: (1) control, (2) 660-nm PBMT, and (3) 808-nm PBMT (GaAlAs laser, 100 J/cm(2), 70 mW, 0.028-cm(2) beam). PBMT was started immediately after surgery and performed once every 3 days during the postoperative period. At the end of the 30-day treatment period, histopathological and histomorphometric evaluations of tissue sections were made under a light and electron microscope. The ratio of the inner axonal diameter to the total outer axonal diameter (g-ratio) and the number of axons per square micrometer were evaluated. In the 808-nm PBMT group, the number of nerve fibers with suboptimal g-ratio ranges of 0-0.49 (p < 0.001) is significantly lower than expected, which indicates better rate of myelinization in the 808-nm PBMT group. The number of axons per square micrometer was significantly higher in the 808-nm PBMT group when compared with the control (p < 0.001) and 660-nm PBMT group (p = 0.010). The data and the histopathological investigations suggest that the PBMT with the 808-nm wavelength along with its settings was able to enhance IAN regeneration after nerve crush injury.en_US
dc.identifier.endpage420en_US
dc.identifier.issn0268-8921en_US
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85068829803en_US
dc.identifier.startpage413en_US
dc.identifier.urihttp://hdl.handle.net/11727/6246
dc.identifier.volume35en_US
dc.identifier.wos000513211100014en_US
dc.language.isoengen_US
dc.relation.isversionof10.1007/s10103-019-02838-wen_US
dc.relation.journalLASERS IN MEDICAL SCIENCEen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPhotobiomodulationen_US
dc.subjectWavelengthen_US
dc.subjectInferior alveolar nerveen_US
dc.subjectNerve injuryen_US
dc.subjectBiostimulationen_US
dc.titleComparative effects of photobiomodulation therapy at wavelengths of 660 and 808 nm on regeneration of inferior alveolar nerve in rats following crush injuryen_US
dc.typearticleen_US

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