Dermoscopy Features of Atypical Fibroxanthoma: A Multicenter Study of The International Dermoscopy Society

dc.contributor.authorMoscarella, Elvira
dc.contributor.authorPiana, Simonetta
dc.contributor.authorSpecchio, Francesca
dc.contributor.authorKyrgidis, Athanassios
dc.contributor.authorNazzaro, Gianluca
dc.contributor.authorEliceche, Maite L.
dc.contributor.authorSavoia, Francesco
dc.contributor.authorBugatti, Leonardo
dc.contributor.authorFilosa, Giorgio
dc.contributor.authorZalaudek, Iris
dc.contributor.authorScarfi, Federica
dc.contributor.authorInskip, Mike
dc.contributor.authorRosendahl, Cliff
dc.contributor.authorPyne, John H.
dc.contributor.authorSiggs, Graeme
dc.contributor.authorCabo, Horatio
dc.contributor.authorDrlik, Lubomir
dc.contributor.authorLallas, Aimilios
dc.contributor.authorLongo, Caterina
dc.contributor.authorArgenziano, Giuseppe
dc.contributor.pubmedID29569417en_US
dc.date.accessioned2023-04-24T11:23:34Z
dc.date.available2023-04-24T11:23:34Z
dc.date.issued2018
dc.description.abstractBackground/Objectives Little is known about the dermoscopic features of atypical fibroxanthoma. Methods Results This was a case-control study. Atypical fibroxanthoma lesions were compared with a control group with non-melanoma skin cancer. Altogether 40 atypical fibroxanthoma were collected. Most developed in men (93%), appearing mainly as nodular (63%), amelanotic (93%) and ulcerated (78%) lesions. Most lesions were located on the scalp (55%) and the ears (13%). Dermoscopically, most atypical fibroxanthoma displayed red (83%) and white (70%) structureless areas and irregular linear vessels (43%). A series of features achieved statistical significance when comparing atypical fibroxanthoma with non-melanoma skin cancer. The presence of red and white structureless areas and white lines, and the absence of yellowish-white opaque scales, hairpin vessels and arborising vessels were predictive of atypical fibroxanthoma in univariate analysis. However, when squamous cell carcinoma was excluded from the analysis, none of the criteria achieved statistical significance. When basal cell carcinoma was excluded, three variables achieved statistical significance in predicting atypical fibroxanthoma: red, structureless areas, the absence of opaque yellowish-white scales and absence of white circles. Conclusions Atypical fibroxanthomas seem to be barely distinguishable from basal cell carcinoma dermoscopically, but they are more easily distinguishable from a well to moderately differentiated squamous cell carcinoma. A histopathological examination is needed for the final diagnosis.en_US
dc.identifier.endpage314en_US
dc.identifier.issn0004-8380en_US
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85044191880en_US
dc.identifier.startpage309en_US
dc.identifier.urihttp://hdl.handle.net/11727/8853
dc.identifier.volume59en_US
dc.identifier.wos000449686900040en_US
dc.language.isoengen_US
dc.relation.isversionof10.1111/ajd.12802en_US
dc.relation.journalAUSTRALASIAN JOURNAL OF DERMATOLOGYen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectatypical fibroxanthomaen_US
dc.subjectdermoscopyen_US
dc.subjectnon-melanoma skin canceren_US
dc.titleDermoscopy Features of Atypical Fibroxanthoma: A Multicenter Study of The International Dermoscopy Societyen_US
dc.typearticleen_US

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