Distribution of Dynamic Forces on Patient Specific Vascular Model:Application of computational Hemodynamics

Abstract

Objective: Recent advances in computerized image processing made the early diagnosis and elective invasive treatment of vascular pathologies possible. However, studies state that the complication rates of elective procedures are higher thatn that the of untreated cases. And, making the decision between protection from life threatening complications and unnecessary interventions is a controversial issue. Therefore, recent studies put emphasis on multidisciplinary motivation,; consequently "computational fluid dynamics" took place in medical simulations. With the aim of setting up hemodynamic forces were discussed in vascular models.

Methods: Three dimensional distribution of hmodynamic forces in aneurisam and stenotic models were computed by uisng two different patient specific simulations which were constructed on two different vessel models of "parametric" and "realistic" approaches.

Results: The results were consistent with almost all common practical knowledge. Continuity and Bernoulli's laws imply that a fluid moving through a wide vessel must move more quickly when the vessel narrows and the pressure decreases gradually. The relation between vessel geometry and velocity vectors in maintained laminor flow conditions was demonstrated. The impacts of radial forces and vessel wall structure on spatial distribution of the displacement in vessel geometry were also shown. Additionally spatial distribution of the axial force of "wall shear stress" which was recently suggested to be a hightly reliable measure was evaluated.

Conclusion: Patient specific simulations that are belived to be the core of the future project of "clinical diagnostic expert systems" will be an important tool; in prescribing patient specific treatment and in the assessment of complications risks.