Prostate Mucinous Carcinoma Treated with Definitive Radiotherapy and Hormonal Therapy: Case Report and Review of the Literature

Abstract

Prostate mucinous carcinoma (MC) is a rare variant of prostate adenocarcinoma that is characterized by large pools of extracellular mucin, which by definition compose at least 25% of the tumor volume.

Prostate MC has 3 subtypes. The most common variant is pure MC; primary signet ring cell carcinoma and MC with signet ring cell are less common variants and are more aggressive than pure MC.

Because of the rarity of prostate MC and conflicting reports regarding the behavior of the disease, the optimal treatment strategy is not clear. Most series report the efficacy of surgery.

We report a rare case of a patient with a large prostate MC that was treated successfully with hormone therapy (HT) and radiotherapy (RT). Treatment response was assessed by dynamic contrast-enhanced magnetic resonance imaging (MRI). (C) 2014 Elsevier Inc. All rights reserved.