Coexistence of restless legs syndrome and multiple sclerosis aggravates anxiety and depression

dc.contributor.authorSevim, Serhan
dc.contributor.authorDemirkiran, Meltem
dc.contributor.authorTerzi, Murat
dc.contributor.authorYuceyar, Nur
dc.contributor.authorTasdelen, Bahar
dc.contributor.authorIdiman, Egemen
dc.contributor.authorKurtuncu, Murat
dc.contributor.authorBoz, Cavit
dc.contributor.authorTuncel, Deniz
dc.contributor.authorKarabudak, Rana
dc.contributor.authorSiva, Aksel
dc.contributor.authorOzcan, Abdulcemal
dc.contributor.authorNeyal, Munife
dc.contributor.authorGoksel Karakurum, Basak
dc.contributor.authorGazaloglu, Gulcan Baran
dc.contributor.authorBalal, Mehmet
dc.contributor.authorSen, Sedat
dc.contributor.authorBaklan, Meltem Alkaya
dc.contributor.authorGunduz, Tuncay
dc.contributor.authorTuncer, Asli
dc.contributor.authorUygunoglu, Ugur
dc.contributor.pubmedID35195221en_US
dc.date.accessioned2022-11-15T12:40:06Z
dc.date.available2022-11-15T12:40:06Z
dc.date.issued2022
dc.description.abstractBackground: Among the comorbidities that accompany multiple sclerosis (MS), restless legs syndrome (RLS) is one of the most common. Anxiety and depression are common psychological comorbidities that impact the quality of life of patients with MS (PwMS), as well as patients with RLS. Objective: To investigate the psychiatric burden of MS and RLS coexistence, we conducted a nationwide, multicenter and cross-sectional survey. Methods: Participants were assessed by using demographic and clinical parameters along with the Hamilton Anxiety and Hamilton Depression Scales (HAM-A and HAM-D). Results: Out of the 1,068 participants, 173 (16.2%) were found to have RLS [RLS(+)] and 895 (83.8%) did not [RLS(-)]. The mean scores for HAM-A and HAM-D were significantly higher among RLS(+) subjects than among RLS(-) subjects (p<0.001 for all variables). Conclusions: According to our data, the presence of RLS in PwMS may increase the occurrence of both anxiety and depression symptoms. Awareness and treatment of RLS in PwMS could possibly reduce the symptoms of psychiatric comorbidities originating from RLS.en_US
dc.identifier.endpage172en_US
dc.identifier.issn0004-282Xen_US
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85128159776en_US
dc.identifier.startpage158en_US
dc.identifier.urihttps://www.scielo.br/j/anp/a/gL979xnhZQZ4Db6Pm8S5zSj/?format=pdf&lang=en
dc.identifier.urihttp://hdl.handle.net/11727/8112
dc.identifier.volume80en_US
dc.identifier.wos000759804200001en_US
dc.language.isoengen_US
dc.relation.isversionof10.1590/0004-282X-ANP-2020-0400en_US
dc.relation.journalARQUIVOS DE NEURO-PSIQUIATRIAen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMultiple Sclerosisen_US
dc.subjectRestless Legs Syndromeen_US
dc.subjectDepressionen_US
dc.subjectAnxietyen_US
dc.subjectMental Disordersen_US
dc.titleCoexistence of restless legs syndrome and multiple sclerosis aggravates anxiety and depressionen_US
dc.typearticleen_US

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